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Available online 23 January 2023, 100934
Author links open overlay panelABSTRACTThe emergence of drug resistance is a primary obstacle for successful chemotherapy. Drugs that target cryptic binding sites (CBSs) represent a novel strategy for overcoming drug resistance. In this short communication, we explain and discuss how the discovery of CBSs and their inhibitors can overcome drug resistance.
KeywordsDrug resistance
Cryptic binding sites
Resistance management
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