Cardiovascular disease (CVD) is the leading cause of death globally, coronary heart disease (CHD) is the main category of it. It has been shown that the urban built environment affects the occurrence of CHD, but most focus on single environmental factors. This study developed two multicomponent Urban Heart Health Environment (UHHE) Indexs (unweighted index and weighted index), which were based on the four main behavioral risk factors for CHD (unhealthy diet, lack of physical activity, smoking, and drinking). And we examined the relationship between the indexs and the prevalence of CHD. The prevalence calculation is based on the database of F Hospital patients, who have had coronary stent implantation (CSI). Furthermore, these single-center data were corrected to reduce underestimation of prevalence. We performed global (Ordinal Least Square) and local (Geographically Weighed Regression) regression analyses to assess the relationship between the two UHHE indexs and CHD prevalence. Both indexs showed a significant negative relationship with CHD prevalence. In its spatial relationship, a non-stationary was discovered. The UHHE indexs may help identify and prioritize geographical areas for CHD prevention and may be beneficial to urban design in China.