Ghazawi FM, Zargham R, Gilardino MS, Sasseville D, Jafarian F. Insights into the pathophysiology of hypertrophic scars and keloids: how do they differ? Adv Skin Wound Care. 2018;31(1):582–95.
Feng Y, Wu JJ, Sun ZL, Liu SY, Zou ML, Yuan ZD, et al. Targeted apoptosis of myofibroblasts by elesclomol inhibits hypertrophic scar formation. EBioMedicine. 2020;54: 102715.
Elsaie ML. Update on management of keloid and hypertrophic scars: a systemic review. J Cosmet Dermatol. 2021;20(9):2729–38.
Darby IA, Desmoulière A. Scar formation: cellular mechanisms. In: Téot L, Mustoe TA, Middelkoop E, Gauglitz GG, editors. Textbook on scar management: state of the art management and emerging technologies. Cham: Springer International Publishing; 2020. p. 19–26.
Hoffmann A, Hoing JL, Newman M, Simman R. Role of hyaluronic acid treatment in the prevention of keloid scarring. 2013.
Lee HJ, Jang YJ. Recent understandings of biology, prophylaxis and treatment strategies for hypertrophic scars and keloids. Int J Mol Sci. 2018;19:3.
Gianatasio C, Abrouk M, Waibel JS. Treatment approaches for treating hypertrophic scars and keloids. Dermatol Rev. 2021;2(1):11–22.
Armour A, Scott PG, Tredget EE. Cellular and molecular pathology of HTS: basis for treatment. Wound Repair Regen. 2007;159(1):S6–17.
Scott PG, Dodd CM, Tredget EE, Ghahary A, Rahemtulla F. Chemical characterization and quantification of proteoglycans in human post-burn hypertrophic and mature scars. Clin Sci (Lond). 1996;90(5):417–25.
Zhang Z, Li XJ, Liu Y, Zhang X, Li YY, Xu WS. Recombinant human decorin inhibits cell proliferation and downregulates TGF-beta1 production in hypertrophic scar fibroblasts. Burns. 2007;33(5):634–41.
Ogawa R. The most current algorithms for the treatment and prevention of hypertrophic scars and keloids: a 2020 update of the algorithms published 10 years ago. Plast Reconstr Surg. 2022;149(1):79e–94e.
Juckett G, Hartman-Adams H. Management of keloids and hypertrophic scars. Am Fam Physician. 2009;80(3):253–60.
Jfri A, Alajmi A. Spontaneous keloids: a literature review. Dermatology. 2018;234(3–4):127–30.
Gauglitz GG, Korting HC, Pavicic T, Ruzicka T, Jeschke MG. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med. 2011;17(1–2):113–25.
Limandjaja GC, Niessen FB, Scheper RJ, Gibbs S. Hypertrophic scars and keloids: overview of the evidence and practical guide for differentiating between these abnormal scars. Exp Dermatol. 2021;30(1):146–61.
Ogawa R, Okai K, Tokumura F, Mori K, Ohmori Y, Huang C, et al. The relationship between skin stretching/contraction and pathologic scarring: the important role of mechanical forces in keloid generation. Wound Repair Regen. 2012;20(2):149–57.
Atkinson JA, McKenna KT, Barnett AG, McGrath DJ, Rudd M. A randomized, controlled trial to determine the efficacy of paper tape in preventing hypertrophic scar formation in surgical incisions that traverse Langer’s skin tension lines. Plast Reconstr Surg. 2005;116(6):1648–56.
Arno AI, Gauglitz GG, Barret JP, Jeschke MG. Up-to-date approach to manage keloids and hypertrophic scars: a useful guide. Burns. 2014;40(7):1255–66.
Ibrahim NE, Shaharan S, Dheansa B. Adverse effects of pregnancy on keloids and hypertrophic scars. Cureus. 2020;12(12): e12154.
Moustafa MF, Abdel-Fattah MA, Abdel-Fattah DC. Presumptive evidence of the effect of pregnancy estrogens on keloid growth: case report. Plast Reconstr Surg. 1975;56(4):450–3.
Macarak EJ, Wermuth PJ, Rosenbloom J, Uitto J. Keloid disorder: fibroblast differentiation and gene expression profile in fibrotic skin diseases. Exp Dermatol. 2021;30(1):132–45.
Chike-Obi CJ, Cole PD, Brissett AE. Keloids: pathogenesis, clinical features, and management. Semin Plast Surg. 2009;23(3):178–84.
Hellwege JN, Russell SB, Williams SM, Edwards TL, Velez Edwards DR. Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation. Ann Hum Genet. 2018;82(4):206–15.
Nakashima M, Chung S, Takahashi A, Kamatani N, Kawaguchi T, Tsunoda T, et al. A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. Nat Genet. 2010;42(9):768–71.
Tulandi T, Al-Sannan B, Akbar G, Ziegler C, Miner L. Prospective study of intraabdominal adhesions among women of different races with or without keloids. Am J Obstet Gynecol. 2011;204(2):132.e1-4.
Young WG, Worsham MJ, Joseph CL, Divine GW, Jones LR. Incidence of keloid and risk factors following head and neck surgery. JAMA Facial Plast Surg. 2014;16(5):379–80.
Lu YY, Lu CC, Yu WW, Zhang L, Wang QR, Zhang CL, et al. Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan. BMJ Open. 2018;8(7): e022865.
Diaz A, Tan K, He H, Xu H, Cueto I, Pavel AB, et al. Keloid lesions show increased IL-4/IL-13 signaling and respond to Th2-targeting dupilumab therapy. J Eur Acad Dermatol Venereol. 2020;34(4):e161–4.
Tirgan MH, Uitto J. Lack of efficacy of dupilumab in the treatment of keloid disorder. J Eur Acad Dermatol Venereol. 2022;36(2):e120–2.
Bran GM, Goessler UR, Hormann K, Riedel F, Sadick H. Keloids: current concepts of pathogenesis (review). Int J Mol Med. 2009;24(3):283–93.
El Kinani M, Duteille F. Scar epidemiology and consequences. In: Téot L, Mustoe TA, Middelkoop E, Gauglitz GG, editors. Textbook on scar management: state of the art management and emerging technologies. Cham: Springer International Publishing; 2020. p. 45–9.
Taylor SC. Epidemiology of skin diseases in ethnic populations. Dermatol Clin. 2003;21(4):601–7.
Rockwell WB, Cohen IK, Ehrlich HP. Keloids and hypertrophic scars: a comprehensive review. Plast Reconstr Surg. 1989;84(5):827–37.
Gangemi EN, Gregori D, Berchialla P, Zingarelli E, Cairo M, Bollero D, et al. Epidemiology and risk factors for pathologic scarring after burn wounds. Arch Facial Plast Surg. 2008;10(2):93–102.
Kruglikov IL, Scherer PE. Caveolin-1 as a target in prevention and treatment of hypertrophic scarring. NPJ Regen Med. 2019;4:9.
Rumsey N, Clarke A, White P. Exploring the psychosocial concerns of outpatients with disfiguring conditions. J Wound Care. 2003;12(7):247–52.
Tripathi S, Soni K, Agrawal P, Gour V, Mondal R, Soni V. Hypertrophic scars and keloids: a review and current treatment modalities. Biomed Dermatol. 2020;4(1):1–11.
Ogawa R, Dohi T, Tosa M, Aoki M, Akaishi S. The latest strategy for keloid and hypertrophic scar prevention and treatment: the Nippon Medical School (NMS) Protocol. J Nippon Med School. 2021;88(1):2–9.
Levenson SM, Geever R EF, Crowley LV, Oates JF 3rd, Berard CW, Rosen H. The Healing Of Rat Skin Wounds. Ann Surg. 1965;161(2):293-308.
Sarrazy V, Billet F, Micallef L, Coulomb B, Desmoulière A. Mechanisms of pathological scarring: Role of myofibroblasts and current developments. Wound Repair Regen. 2011;19:10–5.
Tan ST, Winarto N, Dosan R, Aisyah PB. The benefits of occlusive dressings in wound healing. Open Dermatol J. 2019;13(1):27–33.
Mustoe TA, Gurjala A. The role of the epidermis and the mechanism of action of occlusive dressings in scarring. Wound Repair Regen. 2011;19 Suppl 1(0 1):s16-21.
Hutchinson JJ, McGuckin M. Occlusive dressings: a microbiologic and clinical review. 1990.
de Oliveira GV, Gold MH. Silicone sheets and new gels to treat hypertrophic scars and keloids: A short review. Dermatol Ther. 2020;33(4):e13705.
Perkins K, Davey RB, Wallis KA. Silicone gel: a new treatment for burn scars and contractures. Burns Incl Therm Inj. 1983;9(3):201–4.
O'Shaughnessy KD, De La Garza M, Roy NK, Mustoe TA. Homeostasis of the epidermal barrier layer: a theory of how occlusion reduces hypertrophic scarring. Wound Repair Regen. 2009;17(5):700-8.
De Decker I, Hoeksema H, Verbelen J, Vanlerberghe E, De Coninck P, Speeckaert MM, et al. The use of fluid silicone gels in the prevention and treatment of hypertrophic scars: a systematic review and meta-analysis. Burns. 2022;48(3):491–509.
Wiseman J, Ware RS, Simons M, McPhail S, Kimble R, Dotta A, et al. Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: a randomized controlled trial. Clin Rehabil. 2020;34(1):120–31.
Jenwitheesuk K, Surakunprapha P, Kuptarnond C, Prathanee S, Intanoo W. Role of silicone derivative plus onion extract gel in presternal hypertrophic scar protection: a prospective randomized, double blinded, controlled trial. Int Wound J. 2012;9(4):397–402.
de Giorgi V, Sestini S, Mannone F, Papi F, Alfaioli B, Gori A, et al. The use of silicone gel in the treatment of fresh surgical scars: a randomized study. Clin Exp Dermatol. 2009;34(6):688–93.
Shirazi M, Mohammadi AA, Shamohammadi I, Mahboubi A, Makarem A. Efficacy of silicone gel in reducing scar formation after hypospadias repair: a randomized placebo-controlled trial. Res Rep Urol. 2019;11:291–8.
van der Wal MBA, van Zuijlen PP, van de Ven P, Middelkoop E. Topical silicone gel versus placebo in promoting the maturation of burn scars: a randomized controlled trial. Plast Reconstr Surg. 2010;126(2):524–31.
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