Poulter NR, Prabhakaran D, Caulfield M. Hypertension. Lancet. 2015;386:801–12.
Kakitapalli Y, Ampolu J, Madasu SD, Sai Kumar MLS. Detailed review of chronic kidney disease. Kidney Dis (Basel). 2020;6:85–91.
Udani S, Lazich I, Bakris GL. Epidemiology of hypertensive kidney disease. Nat Rev Nephrol. 2011;7:11–21.
Wright JT Jr., Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, et al. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA. 2002;288:2421–31.
Ruggenenti P, Perna A, Loriga G, Ganeva M, Ene-Iordache B, Turturro M, et al. Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial. Lancet. 2005;365:939–46.
Ku E, Glidden DV, Johansen KL, Sarnak M, Tighiouart H, Grimes B, et al. Association between strict blood pressure control during chronic kidney disease and lower mortality after onset of end-stage renal disease. Kidney Int. 2015;87:1055–60.
Vieira-Rocha MS, Sousa JB, Rodriguez-Rodriguez P, Morato M, Arribas SM, Diniz C. Insights into sympathetic nervous system and GPCR interplay in fetal programming of hypertension: a bridge for new pharmacological strategies. Drug Discov Today. 2020;25:739–47.
Brinks HL, Eckhart AD. Regulation of GPCR signaling in hypertension. Biochim Biophys Acta. 2010;1802:1268–75.
Cui X, Shi E, Li J, Li Y, Qiao Z, Wang Z, et al. GPR87 promotes renal tubulointerstitial fibrosis by accelerating glycolysis and mitochondrial injury. Free Radic Biol Med. 2022;189:58–70.
Yona S, Lin HH, Siu WO, Gordon S, Stacey M. Adhesion-GPCRs: emerging roles for novel receptors. Trends Biochem Sci. 2008;33:491–500.
Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736–48.
Wang JJ, Zhang LL, Zhang HX, Shen CL, Lu SY, Kuang Y, et al. Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision. Cell Death Dis. 2013;4:e853.
Causton B, Ramadas RA, Cho JL, Jones K, Pardo-Saganta A, Rajagopal J, et al. CARMA3 Is critical for the initiation of allergic airway inflammation. J Immunol. 2015;195:683–94.
Zugasti O, Bose N, Squiban B, Belougne J, Kurz CL, Schroeder FC, et al. Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Nat Immunol. 2014;15:833–8.
Fang W, Wang Z, Li Q, Wang X, Zhang Y, Sun Y, et al. Gpr97 Exacerbates AKI by Mediating Sema3A Signaling. J Am Soc Nephrol. 2018;29:1475–89.
Boese AC, Kim SC, Yin KJ, Lee JP, Hamblin MH. Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease. Am J Physiol Heart Circ Physiol. 2017;313:H524–H45.
Caroccia B, Seccia TM, Barton M, Rossi GP. Estrogen signaling in the adrenal cortex: implications for blood pressure sex differences. Hypertension. 2016;68:840–8.
Ma MM, Gao M, Guo KM, Wang M, Li XY, Zeng XL, et al. Estrogen signaling in the adrenal cortex: implications for blood pressure sex differences. Hypertension. 2017;69:892–901.
Yi F, Zhang AY, Janscha JL, Li PL, Zou AP. Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells. Kidney Int. 2004;66:1977–87.
Sun Y, Guan J, Hou Y, Xue F, Huang W, Zhang W, et al. Silencing of junctional adhesion molecule-like protein attenuates atherogenesis and enhances plaque stability in ApoE(-/-) mice. Clin Sci. 2019;133:1215–28.
Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem. 2003;278:21113–23.
Zhao B, Chen YG. Regulation of TGF-beta signal transduction. Sci (Cairo). 2014;2014:874065.
Loebrich S. The role of F-actin in modulating Clathrin-mediated endocytosis: Lessons from neurons in health and neuropsychiatric disorder. Commun Integr Biol. 2014;7:e28740.
Hall A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu Rev Cell Biol. 1994;10:31–54.
Kim JG, Islam R, Cho JY, Jeong H, Cap KC, Park Y, et al. Regulation of RhoA GTPase and various transcription factors in the RhoA pathway. J Cell Physiol. 2018;233:6381–92.
Tumbarello DA, Turner CE. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. J Cell Physiol. 2007;211:736–47.
Raina R, Chauvin A, Chakraborty R, Nair N, Shah H, Krishnappa V, et al. The Role of Endothelin and Endothelin Antagonists in Chronic Kidney Disease. Kidney Dis. 2020;6:22–34.
Seccia TM, Caroccia B, Calo LA. Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms. J Hypertens. 2017;35:205–12.
Costantino VV, Gil Lorenzo AF, Bocanegra V, Valles PG. Molecular mechanisms of hypertensive nephropathy: renoprotective effect of losartan through Hsp70. Cells. 2021;10:3146.
Lopez-Haber C, Barrio-Real L, Casado-Medrano V, Kazanietz MG. Heregulin/ErbB3 signaling enhances CXCR4-driven Rac1 activation and breast cancer cell motility via hypoxia-inducible factor 1alpha. Mol Cell Biol. 2016;36:2011–26.
Recchia AG, De Francesco EM, Vivacqua A, Sisci D, Panno ML, Ando S, et al. The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes. J Biol Chem. 2011;286:10773–82.
Welch WJ, Baumgartl H, Lubbers D, Wilcox CS. Nephron pO2 and renal oxygen usage in the hypertensive rat kidney. Kidney Int. 2001;59:230–7.
Palm F, Onozato M, Welch WJ, Wilcox CS. Blood pressure, blood flow, and oxygenation in the clipped kidney of chronic 2-kidney, 1-clip rats: effects of tempol and angiotensin blockade. Hypertension. 2010;55:298–304.
Welch WJ. Intrarenal oxygen and hypertension. Clin Exp Pharm Physiol. 2006;33:1002–5.
Palm F, Nordquist L. Renal tubulointerstitial hypoxia: cause and consequence of kidney dysfunction. Clin Exp Pharmacol Physiol. 2011;38:474–80.
Rozen-Zvi B, Hayashida T, Hubchak SC, Hanna C, Platanias LC, Schnaper HW. TGF-beta/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1alpha expression. Am J Physiol Ren Physiol. 2013;305:F485–94.
Gewin L. The many talents of transforming growth factor-beta in the kidney. Curr Opin Nephrol Hypertens. 2019;28:203–10.
Yan Y, Wang J, Chaudhry MA, Nie Y, Sun S, Carmon J, et al. Metabolic syndrome and salt-sensitive hypertension in polygenic obese TALLYHO/JngJ mice: role of Na/K-ATPase signaling. Int J Mol Sci. 2019;20:3495.
Cao J, Hou R, Lu J, Zhang K, Zhao C, Jiang H, et al. The predictive value of beta2-MG and TGF-beta for elderly hypertensive nephropathy. Exp Ther Med. 2019;17:3065–70.
Chen YG. Endocytic regulation of TGF-beta signaling. Cell Res. 2009;19:58–70.
Mitchell H, Choudhury A, Pagano RE, Leof EB. Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11. Mol Biol Cell. 2004;15:4166–78.
Yarar D, Waterman-Storer CM, Schmid SL. A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis. Mol Biol Cell. 2005;16:964–75.
Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci USA. 2012;109:E2441–50.
Peng F, Zhang B, Wu D, Ingram AJ, Gao B, Krepinsky JC. TGFbeta-induced RhoA activation and fibronectin production in mesangial cells require caveolae. Am J Physiol Ren Physiol. 2008;295:F153–64.
Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H. Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem. 2008;283:14469–78.
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