Response to Letter “Therapeutic Hypothermia for Neonatal Encephalopathy in Low-Resource Settings: Methodological Inaccuracies and Inconsistencies in the Latest Systematic Review”

Bellos I.a· Pandita A.b

Author affiliations

aNational and Kapodistrian University of Athens, Athens, Greece
bDepartment of Neonatology, Medanta Hospital, Lucknow, India

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Article / Publication Details

Received: August 08, 2022
Accepted: August 09, 2022
Published online: January 10, 2023

Number of Print Pages: 2
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO


First-Page Preview
Abstract of Reply References Matthew JL, Kaur N, Dsouza JM. Therapeutic hypothermia for neonatal encephalopathy in low-resource settings: methodological inaccuracies and inconsistencies in the latest systematic review. Neonatolotgy. 2022. Bellos I, Devi U, Pandita A. Therapeutic hypothermia for neonatal encephalopathy in low- and middle-income countries: a meta-analysis. Neonatology. 2022;119(3):300–10. Catherine RC, Ballambattu VB, Adhisivam B, Bharadwaj SK, Palanivel C. Effect of therapeutic hypothermia on the outcome in term neonates with hypoxic ischemic encephalopathy-a randomized controlled trial. J Trop Pediatr. 2021;67(1):fmaa073. McCoy E. Understanding the intention-to-treat principle in randomized controlled trials. WestJEM. 2017;18(6):1075–8. Thompson SG. Systematic Review: why sources of heterogeneity in meta-analysis should be investigated. BMJ. 1994;309(6965):1351–5. Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane handbook for systematic reviews of interventions version 6.0. Cochrane Training; 2019 [updated July 2019]. Available from: www.training.cochrane.org/handbook. Chen X, Peng W, Zhang Z, Zhao Q, Zhou Y, Chen L. Efficacy and safety of selective brain hypothermia therapy on neonatal hypoxic-ischemic encephalopathy. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018;30(11):1046–50. El Shimi MS, Awad HA, Hassanein SMA, Gad GI, Imam SS, Shaaban HA. Single dose recombinant erythropoietin versus moderate hypothermia for neonatal hypoxic ischemic encephalopathy in low resource settings. J Maternal-Fetal Neonatal Med. 2014;27(13):1295–300. Yang T, Li S. Efficacy of different treatment times of mild cerebral hypothermia on oxidative factors and neuroprotective effects in neonatal patients with moderate/severe hypoxic-ischemic encephalopathy. J Int Med Res. 2020;48(9). Tanigasalam V, Bhat V, Adhisivam B, Sridhar MG. Does therapeutic hypothermia reduce acute kidney injury among term neonates with perinatal asphyxia?: a randomized controlled trial. J Matern Fetal Neonatal Med. 2016;29(15):2545–8. Rakesh K, Vishnu Bhat B, Adhisivam B, Ajith P. Effect of therapeutic hypothermia on myocardial dysfunction in term neonates with perinatal asphyxia: a randomized controlled trial. J Maternal-Fetal Neonatal Med. 2018;31(18):2418–23. Thayyil S, Shankaran S, Wade A, Cowan FM, Ayer M, Satheesan K, et al. Whole-body cooling in neonatal encephalopathy using phase changing material. Arch Dis Child Fetal Neonatal Ed. 2013;98(3):F280–1. Epub ahead of print. Bhat MA. Re: therapeutic hypothermia following perinatal asphyxia. Arch Dis Child Fetal Neonatal Ed. 2006;91(6):F464. Article / Publication Details

Received: August 08, 2022
Accepted: August 09, 2022
Published online: January 10, 2023

Number of Print Pages: 2
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO

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