Silencing of Long Noncoding RNA TUG1 Ameliorates Atherosclerosis-Induced Myocardial Injury by Upregulating microRNA-30b-3p and Downregulating Brd4

*Department of Cardiology, Fujian Medical University Affiliated First Quanzhou Hospital, Quanzhou, Fujian, China;

†Department of Gastroscope, Fujian Medical University Affiliated First Quanzhou Hospital, Quanzhou, Fujian, China;

‡Central laboratory, The First Affiliated Hospital Of Xiamen University, Xiamen Diabetes Institute, Xiamen, Fujian, China; and

§Cardiovascular Medicine, The Affiliated Cardiovascular Hospital of Xiamen University, Xiamen, Fujian, China.

Correspondence: Ruo-zhu Dai, MD, Department of Cardiology, Fujian Medical University Affiliated First Quanzhou Hospital, 1028 Anji South Rd, Fengze District, Quanzhou, 362000, Fujian, China (e-mail: [email protected]).

The authors report no conflicts of interest.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.jcvp.org).

R. -z. Dai constituted study design, D. -l. Li, B. -b. Zheng performed experimental studies, D. -l. Li, X. Zeng, J. Li conducted data analysis, and J. Shao, D. -l. Li finished manuscript editing. All authors read and approved the final manuscript

Animal experiments were conducted strictly in accordance with the Guide to the Management and Use of Laboratory Animals. The protocol of animal experiments was approved by the Institutional Animal Care and Use Committee of Fujian Medical University Affiliated First Quanzhou Hospital.

The data that support the findings of this study are available from the corresponding author on reasonable request.

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