Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: The next generation. Cell, 144(5), 646–674.
Hanahan, D., & Weinberg, R. A. (2000). The hallmarks of cancer. Cell, 100(1), 57–70.
Hanahan, D. (2022). Hallmarks of cancer: New dimensions. Cancer Discovery, 12(1), 31–46.
Friberg, S., & Nystrom, A. (2015). Cancer metastases: early dissemination and late recurrences. Cancer Growth Metastasis, 8, 43–9.
Willis, R.A., The spread of tumours in the human body. 1934: J. & A. Churchill.
Hadfield, G. (1954). The dormant cancer cell. British Medical Journal, 2(4888), 607–610.
Hosseini, H., et al. (2016). Early dissemination seeds metastasis in breast cancer. Nature, 540(7634), 552–558.
Phan, T. G., & Croucher, P. I. (2020). The dormant cancer cell life cycle. Nature Reviews Cancer, 20(7), 398–411.
Aguirre-Ghiso, J. A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nature Reviews Cancer, 7(11), 834–846.
Santos-de-Frutos, K., & Djouder, N. (2021). When dormancy fuels tumour relapse. Communication Biology, 4(1), 747.
Giancotti, F. G. (2013). Mechanisms governing metastatic dormancy and reactivation. Cell, 155(4), 750–764.
Aguirre-Ghiso, J. A. (2018). How dormant cancer persists and reawakens. Science, 361(6409), 1314–1315.
Aguirre-Ghiso, J. A. (2021). Translating the science of cancer dormancy to the clinic. Cancer Research, 81(18), 4673–4675.
Summers, M.A., McDonald M.M., & Croucher P.I. (2020). Cancer cell dormancy in metastasis. Cold Spring Harbor Perspectives in Medicine, 10(4).
Holmgren, L., O’Reilly, M. S., & Folkman, J. (1995). Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nature Medicine, 1(2), 149–153.
Townson, J. L., & Chambers, A. F. (2006). Dormancy of solitary metastatic cells. Cell Cycle, 5(16), 1744–1750.
Sosa, M. S., Bragado, P., & Aguirre-Ghiso, J. A. (2014). Mechanisms of disseminated cancer cell dormancy: An awakening field. Nature Reviews Cancer, 14(9), 611–622.
Risson, E., et al. (2020). The current paradigm and challenges ahead for the dormancy of disseminated tumor cells. Nature Cancer, 1(7), 672–680.
Hayflick, L. (1965). The limited in vitro lifetime of human diploid cell strains. Experimental Cell Research, 37, 614–36.
Hayflick, L., & Moorhead, P. S. (1961). The serial cultivation of human diploid cell strains. Experimental Cell Research, 25, 585–621.
Masutomi, K., et al. (2003). Telomerase maintains telomere structure in normal human cells. Cell, 114(2), 241–253.
Adda di Fagagna, F., et al. (2003). A DNA damage checkpoint response in telomere initiated senescence. Nature, 426(6963), 194–8.
Takai, H., Smogorzewska, A., & de Lange, T. (2003). DNA damage foci at dysfunctional telomeres. Current Biology, 13(17), 1549–1556.
Herbig, U., et al. (2004). Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Molecular Cell, 14(4), 501–513.
Rodier, F., & Campisi, J. (2011). Four faces of cellular senescence. Journal of Cell Biology, 192(4), 547–556.
Dimri, G. P., et al. (2000). Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor. Molecular and Cellular Biology, 20(1), 273–285.
Lin, A. W., et al. (1998). Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12(19), 3008–3019.
Serrano, M., et al. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88(5), 593–602.
Zhu, J., et al. (1998). Senescence of human fibroblasts induced by oncogenic Raf. Genes & Development, 12(19), 2997–3007.
Di Micco, R., et al. (2006). Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature, 444(7119), 638–642.
Schmitt, C. A., et al. (2002). A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell, 109(3), 335–346.
Rodier, F., et al. (2009). Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nature Cell Biology, 11(8), 973–979.
Le, O. N., et al. (2010). Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell, 9(3), 398–409.
Gire, V., & Dulic, V. (2015). Senescence from G2 arrest, revisited. Cell Cycle, 14(3), 297–304.
Kuilman, T., et al. (2010). The essence of senescence. Genes & Development, 24(22), 2463–2479.
Hernandez-Segura, A., Nehme, J., & Demaria, M. (2018). Hallmarks of Cellular Senescence. Trends in Cell Biology, 28(6), 436–453.
Rajagopalan, S., & Long, E. O. (2012). Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling. Proceedings of the National Academy of Sciences USA, 109(50), 20596–20601.
Munoz-Espin, D., et al. (2013). Programmed cell senescence during mammalian embryonic development. Cell, 155(5), 1104–1118.
Storer, M., et al. (2013). Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell, 155(5), 1119–1130.
Jun, J. I., & Lau, L. F. (2010). Cellular senescence controls fibrosis in wound healing. Aging (Albany NY), 2(9), 627–631.
Kong, X., et al. (2012). Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice. Hepatology, 56(3), 1150–1159.
Demaria, M., et al. (2014). An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Developmental Cell, 31(6), 722–733.
Krizhanovsky, V., et al. (2008). Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology. Cold Spring Harbor Symposium Quant Biology, 73, 513–22.
Krizhanovsky, V., et al. (2008). Senescence of activated stellate cells limits liver fibrosis. Cell, 134(4), 657–667.
Childs, B. G., et al. (2014). Senescence and apoptosis: Dueling or complementary cell fates? EMBO Reports, 15(11), 1139–1153.
Baker, D. J., et al. (2011). Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature, 479(7372), 232–236.
Halazonetis, T. D., Gorgoulis, V. G., & Bartek, J. (2008). An oncogene-induced DNA damage model for cancer development. Science, 319(5868), 1352–1355.
Burd, C. E., et al. (2013). Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model. Cell, 152(1–2), 340–351.
Ewald, J. A., et al. (2010). Therapy-induced senescence in cancer. Journal of the National Cancer Institute, 102(20), 1536–1546.
留言 (0)