Assessment of the Frequency, Phenotypes, and Outcomes of Acute Liver Injury Associated with Amoxicillin/Clavulanate in 1.4 Million Patients in the Veterans Health Administration

Bjornsson ES, Bergmann OM, Bjornsson HK, Kvaran RB, Olafsson S. Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland. Gastroenterology. 2013;144(7):1419–25 (25.e1–3; quiz e19–20).

Article  Google Scholar 

Sgro C, Clinard F, Ouazir K, Chanay H, Allard C, Guilleminet C, et al. Incidence of drug-induced hepatic injuries: a French population-based study. Hepatology. 2002;36(2):451–5.

Article  Google Scholar 

Goldberg DS, Forde KA, Carbonari DM, Lewis JD, Leidl KB, Reddy KR, et al. Population-representative incidence of drug-induced acute liver failure based on an analysis of an integrated health care system. Gastroenterology. 2015;148(7):1353-61.e3.

Article  Google Scholar 

Bjornsson ES, Hoofnagle JH. Categorization of drugs implicated in causing liver injury: critical assessment based on published case reports. Hepatology. 2016;63(2):590–603.

Article  Google Scholar 

Aithal GP. Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice. Liver Int. 2015;35(7):1801–8.

Article  CAS  Google Scholar 

Kullak-Ublick GA, Andrade RJ, Merz M, End P, Benesic A, Gerbes AL, et al. Drug-induced liver injury: recent advances in diagnosis and risk assessment. Gut. 2017;66(6):1154–64.

Article  CAS  Google Scholar 

Andrade RJ, Lucena MI, Fernandez MC, Pelaez G, Pachkoria K, Garcia-Ruiz E, et al. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology. 2005;129(2):512–21.

Article  Google Scholar 

Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, et al. Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study. Gastroenterology. 2015;148(7):1340-52.e7.

Article  Google Scholar 

Devarbhavi H, Joseph T, Sunil Kumar N, Rathi C, Thomas V, Prasad Singh S, et al. The Indian network of drug-induced liver injury: etiology, clinical features, outcome and prognostic markers in 1288 patients. J Clin Exp Hepatol. 2021;11(3):288–98.

Article  Google Scholar 

Noel PH, Copeland LA, Perrin RA, Lancaster AE, Pugh MJ, Wang CP, et al. VHA Corporate Data Warehouse height and weight data: opportunities and challenges for health services research. J Rehabil Res Dev. 2010;47(8):739–50.

Article  Google Scholar 

Shin J, Hunt CM, Suzuki A, Papay JI, Beach KJ, Cheetham TC. Characterizing phenotypes and outcomes of drug-associated liver injury using electronic medical record data. Pharmacoepidemiol Drug Saf. 2013;22(2):190–8.

Article  Google Scholar 

Hoofnagle JH, Bjornsson ES. Drug-induced liver injury: types and phenotypes. N Engl J Med. 2019;381(3):264–73.

Article  CAS  Google Scholar 

Aithal GP, Watkins PB, Andrade RJ, Larrey D, Molokhia M, Takikawa H, et al. Case definition and phenotype standardization in drug-induced liver injury. Clin Pharmacol Ther. 2011;89(6):806–15.

Article  CAS  Google Scholar 

Danan G, Benichou C. Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. Journal of clinical epidemiology. 1993; 46(11): 1323-1330

Temple R. Hy’s law: predicting serious hepatotoxicity. Pharmacoepidemiol Drug Saf. 2006;15(4):241–3.

Article  Google Scholar 

US FDA. Guidance for industry. Drug-induced liver injury: premarketing clinical evaluation. 2009. http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/default.htm. Accessed 18 Nov 2022.

Meier Y, Cavallaro M, Roos M, Pauli-Magnus C, Folkers G, Meier PJ, et al. Incidence of drug-induced liver injury in medical inpatients. Eur J Clin Pharmacol. 2005;61(2):135–43.

Article  Google Scholar 

Kang Y, Kim SH, Park SY, Park BY, Lee JH, An J, et al. Evaluation of drug-induced liver injury developed during hospitalization using electronic health record (EHR)-based algorithm. Allergy Asthma Immunol Res. 2020;12(3):430–42.

Article  CAS  Google Scholar 

Mahlab-Guri K, Otman MS, Replianski N, Rosenberg-Bezalel S, Rabinovich I, Sthoeger Z. Venous thromboembolism prophylaxis in patients hospitalized in medical wards: a real life experience. Medicine (Baltimore). 2020;99(7): e19127.

Article  Google Scholar 

Benge CD, Yost AP. Venous thromboembolism prophylaxis in acutely ill veterans with respiratory disease. Fed Pract. 2015;32(4):30–7.

Google Scholar 

Harrill AH, Roach J, Fier I, Eaddy JS, Kurtz CL, Antoine DJ, et al. The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers. Clin Pharmacol Ther. 2012;92(2):214–20.

Article  CAS  Google Scholar 

Lucena MI, Andrade RJ, Fernandez MC, Pachkoria K, Pelaez G, Duran JA, et al. Determinants of the clinical expression of amoxicillin-clavulanate hepatotoxicity: a prospective series from Spain. Hepatology. 2006;44(4):850–6.

Article  CAS  Google Scholar 

deLemos AS, Ghabril M, Rockey DC, Gu J, Barnhart HX, Fontana RJ, et al. Amoxicillin-clavulanate-induced liver injury. Dig Dis Sci. 2016;61(8):2406–16.

Article  CAS  Google Scholar 

Lucena MI, Andrade RJ, Kaplowitz N, Garcia-Cortes M, Fernandez MC, Romero-Gomez M, et al. Phenotypic characterization of idiosyncratic drug-induced liver injury: the influence of age and sex. Hepatology. 2009;49(6):2001–9.

Article  Google Scholar 

Weersink RA, Alvarez-Alvarez I, Medina-Caliz I, Sanabria-Cabrera J, Robles-Diaz M, Ortega-Alonso A, et al. Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old. Clin Pharmacol Ther. 2021;109(4):1147–58.

Article  CAS  Google Scholar 

Gonzalez-Jimenez A, Suzuki A, Chen M, Ashby K, Alvarez-Alvarez I, Andrade RJ, et al. Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach. Arch Toxicol. 2021;95(5):1793–803.

Article  CAS  Google Scholar 

Schmucker DL, Sanchez H. Liver regeneration and aging: a current perspective. Curr Gerontol Geriatr Res. 2011;2011: 526379.

Article  Google Scholar 

Brown GR, Persley K. Hepatitis A epidemic in the elderly. South Med J. 2002;95(8):826–33.

Article  Google Scholar 

Stephens C, Robles-Diaz M, Medina-Caliz I, Garcia-Cortes M, Ortega-Alonso A, Sanabria-Cabrera J, et al. Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry. J Hepatol. 2021;75(1):86–97.

Article  CAS  Google Scholar 

M’Kada H, Perazzo H, Munteanu M, Ngo Y, Ramanujam N, Fautrel B, et al. Real time identification of drug-induced liver injury (DILI) through daily screening of ALT results: a prospective pilot cohort study. PLoS ONE. 2012;7(8): e42418.

Article  CAS  Google Scholar 

Wing K, Bhaskaran K, Pealing L, Root A, Smeeth L, van Staa TP, et al. Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study. J Antimicrob Chemother. 2017;72(9):2636–46.

Article  CAS  Google Scholar 

Chalasani N, Reddy KRK, Fontana RJ, Barnhart H, Gu J, Hayashi PH, et al. Idiosyncratic drug induced liver injury in African-Americans is associated with greater morbidity and mortality compared to Caucasians. Am J Gastroenterol. 2017;112(9):1382–8.

Article  CAS  Google Scholar 

Aithal GP, Rawlins MD, Day CP. Accuracy of hepatic adverse drug reaction reporting in one English health region. BMJ. 1999;319(7224):1541.

Article  CAS  Google Scholar 

Teschke R. Idiosyncratic DILI: analysis of 46,266 cases assessed for causality by RUCAM and published from 2014 to early 2019. Front Pharmacol. 2019;10:730.

Article  Google Scholar 

Ditah I, Ditah F, Devaki P, Ditah C, Kamath PS, Charlton M. Current epidemiology of hepatitis E virus infection in the United States: low seroprevalence in the National Health and Nutrition Evaluation Survey. Hepatology. 2014;60(3):815–22.

Article  Google Scholar 

Bjornsson HK, Gudmundsson DO, Bjornsson ES. Liver injury caused by oral anticoagulants: a population-based retrospective cohort study. Liver Int. 2020;40(8):1895–900.

Article  Google Scholar 

Tsung I, Dolan R, Lao CD, Fecher L, Riggenbach K, Yeboah-Korang A, et al. Liver injury is most commonly due to hepatic metastases rather than drug hepatotoxicity during pembrolizumab immunotherapy. Aliment Pharmacol Ther. 2019;50(7):800–8.

Article  CAS  Google Scholar 

Koch DG, Speiser JL, Durkalski V, Fontana RJ, Davern T, McGuire B, et al. The natural history of severe acute liver injury. Am J Gastroenterol. 2017;112(9):1389–96.

Article  Google Scholar 

Benichou C. Criteria of drug-induced liver disorders: report of an international consensus meeting. J Hepatol. 1990;11(2):272–6.

Article  CAS  Google Scholar 

留言 (0)

沒有登入
gif