Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., et al. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249, https://doi.org/10.3322/caac.21660.
Hanahan, D. (2022). Hallmarks of cancer: New dimensions. Cancer Discovery, 12(1), 31–46. https://doi.org/10.1158/2159-8290.CD-21-1059
Hanahan, D., & Weinberg, R. A. (2011). Hallmarks of cancer: The next generation. Cell, 144(5), 646–674. https://doi.org/10.1016/j.cell.2011.02.013
Arora, L., Kumar, A. P., Arfuso, F., Chng, W. J., & Sethi, G. (2018). The role of signal transducer and activator of transcription 3 (STAT3) and its targeted inhibition in hematological malignancies. Cancers, 10(9), 327. https://doi.org/10.3390/cancers10090327
Bushweller, J. H. (2019). Targeting transcription factors in cancer - From undruggable to reality. Nature Reviews Cancer, 19(11), 611–624. https://doi.org/10.1038/s41568-019-0196-7
Garg, M., Shanmugam, M. K., Bhardwaj, V., Goel, A., Gupta, R., Sharma, A., et al. (2021). The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy. Medicinal Research Reviews, 41(3), 1291–1336. https://doi.org/10.1002/med.21761
Mirzaei, S., Zarrabi, A., Hashemi, F., Zabolian, A., Saleki, H., Ranjbar, A., et al. (2021). Regulation of nuclear factor-kappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis? Cancer Letters, 509, 63–80. https://doi.org/10.1016/j.canlet.2021.03.025
Dhiman, V. K., Bolt, M. J., & White, K. P. (2018). Nuclear receptors in cancer—Uncovering new and evolving roles through genomic analysis. Nature Reviews Genetics, 19(3), 160–174. https://doi.org/10.1038/nrg.2017.102
Jayaprakash, S., Hegde, M., Girisa, S., Alqahtani, M. S., Abbas, M., Lee, E. H. C., et al. (2022). Demystifying the functional role of nuclear receptors in esophageal cancer. International Journal of Molecular Sciences, 23(18), 10952. https://doi.org/10.3390/ijms231810952.
Gangwar, S. K., Kumar, A., Jose, S., Alqahtani, M. S., Abbas, M., Sethi, G., et al. (2022). Nuclear receptors in oral cancer-Emerging players in tumorigenesis. Cancer Letters, 536, 215666. https://doi.org/10.1016/j.canlet.2022.215666
Gangwar, S. K., Kumar, A., Yap, K. C., Jose, S., Parama, D., Sethi, G., et al. (2022). Targeting nuclear receptors in lung cancer-Novel therapeutic prospects. Pharmaceuticals (Basel), 15(5), https://doi.org/10.3390/ph15050624.
Girisa, S., Rana, V., Parama, D., Dutta, U., & Kunnumakkara, A. B. (2021). Differential roles of farnesoid X receptor (FXR) in modulating apoptosis in cancer cells. Advances in Protein Chemistry and Structural Biology, 126, 63–90. https://doi.org/10.1016/bs.apcsb.2021.02.006
Girisa, S., Henamayee, S., Parama, D., Rana, V., Dutta, U., & Kunnumakkara, A. B. (2021). Targeting farnesoid X receptor (FXR) for developing novel therapeutics against cancer. Molecular Biomedecine, 2(1), 21. https://doi.org/10.1186/s43556-021-00035-2
Tang, Q., Chen, Y., Meyer, C., Geistlinger, T., Lupien, M., Wang, Q., et al. (2011). A comprehensive view of nuclear receptor cancer cistromes. Cancer Research, 71(22), 6940–6947. https://doi.org/10.1158/0008-5472.CAN-11-2091
Santagata, S., Thakkar, A., Ergonul, A., Wang, B., Woo, T., Hu, R., et al. (2014). Taxonomy of breast cancer based on normal cell phenotype predicts outcome. The Journal of Clinical Investigation, 124(2), 859–870. https://doi.org/10.1172/JCI70941
Font-Diaz, J., Jimenez-Panizo, A., Caelles, C., Vivanco, M. D., Perez, P., Aranda, A., et al. (2021). Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development. Seminars in Cancer Biology, 73, 58–75. https://doi.org/10.1016/j.semcancer.2020.12.007
Zhao, L., Zhou, S., & Gustafsson, J. -Å. (2019). Nuclear receptors: Recent drug discovery for cancer therapies. Endocrine Reviews, 40(5), 1207–1249.
Burris, T. P., Solt, L. A., Wang, Y., Crumbley, C., Banerjee, S., Griffett, K., et al. (2013). Nuclear receptors and their selective pharmacologic modulators. Pharmacological Reviews, 65(2), 710–778. https://doi.org/10.1124/pr.112.006833
Ishigami-Yuasa, M., & Kagechika, H. (2020). Chemical screening of nuclear receptor modulators. International Journal of Molecular Sciences, 21(15), 5512. https://doi.org/10.3390/ijms21155512
Knapp, P., Gardner, P. H., Raynor, D. K., Woolf, E., & McMillan, B. (2010). Perceived risk of tamoxifen side effects: A study of the use of absolute frequencies or frequency bands, with or without verbal descriptors. Patient Education and Counseling, 79(2), 267–271.
Pratheeshkumar, P., Sreekala, C., Zhang, Z., Budhraja, A., Ding, S., Son, Y.-O., et al. (2012). Cancer prevention with promising natural products: Mechanisms of action and molecular targets. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 12(10), 1159–1184.
Harsha, C., Banik, K., Bordoloi, D., & Kunnumakkara, A. B. (2017). Antiulcer properties of fruits and vegetables: A mechanism based perspective. Food and Chemical Toxicology, 108, 104–119.
Elkordy, A. A., Haj-Ahmad, R. R., Awaad, A. S., & Zaki, R. M. (2021). An overview on natural product drug formulations from conventional medicines to nanomedicines: Past, present and future. Journal of Drug Delivery Science and Technology, 63, 102459.
Kunnumakkara, A. B., Nair, A. S., Ahn, K. S., Pandey, M. K., Yi, Z., Liu, M., et al. (2007). Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood, 109(12), 5112–5121. https://doi.org/10.1182/blood-2007-01-067256
Muralimanoharan, S. B., Kunnumakkara, A. B., Shylesh, B., Kulkarni, K. H., Haiyan, X., Ming, H., et al. (2009). Butanol fraction containing berberine or related compound from nexrutine inhibits NFkappaB signaling and induces apoptosis in prostate cancer cells. Prostate, 69(5), 494–504. https://doi.org/10.1002/pros.20899
Kunnumakkara, A. B., Sung, B., Ravindran, J., Diagaradjane, P., Deorukhkar, A., Dey, S., et al. (2012). Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets. International Journal of Cancer, 131(3), E292-303. https://doi.org/10.1002/ijc.26442
Huang, M., Lu, J.-J., & Ding, J. (2021). Natural products in cancer therapy: Past, present and future. Natural Products and Bioprospecting, 11(1), 5–13.
Huang, M.-Y., Zhang, L.-L., Ding, J., & Lu, J.-J. (2018). Anticancer drug discovery from Chinese medicinal herbs. Chinese Medicine, 13(1), 1–9.
Newman, D. J., & Cragg, G. M. (2020). Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. Journal of Natural Products, 83(3), 770–803.
Liu, C., Ho, P.C.-L., Wong, F. C., Sethi, G., Wang, L. Z., & Goh, B. C. (2015). Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects. Cancer Letters, 362(1), 8–14.
Kirtonia, A., Gala, K., Fernandes, S. G., Pandya, G., Pandey, A. K., Sethi, G., et al. Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. In Seminars in Cancer Biology, 2021 (Vol. 68, pp. 258–278): Elsevier
Huang, P. X., Chandra, V., & Rastinejad, F. (2010). Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics. Annual Review of Physiology, 72, 247–272. https://doi.org/10.1146/annurev-physiol-021909-135917
Papacleovoulou, G., Abu-Hayyeh, S., & Williamson, C. (2011). Nuclear receptor-driven alterations in bile acid and lipid metabolic pathways during gestation. Biochimica et Biophysica Acta, 1812(8), 879–887. https://doi.org/10.1016/j.bbadis.2010.11.001
Choi, J. M., & Bothwell, A. L. M. (2012). The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases. Molecules and Cells, 33(3), 217–222. https://doi.org/10.1007/s10059-012-2297-y
Nagy, Z. S., Czimmerer, Z., & Nagy, L. (2013). Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism. Molecular and Cellular Endocrinology, 368(1–2), 85–98. https://doi.org/10.1016/j.mce.2012.04.003
Jin, Z., Li, X., & Wan, Y. (2015). Minireview: Nuclear receptor regulation of osteoclast and bone remodeling. Molecular Endocrinology, 29(2), 172–186. https://doi.org/10.1210/me.2014-1316
Yin, K., & Smith, A. G. (2016). Nuclear receptor function in skin health and disease: Therapeutic opportunities in the orphan and adopted receptor classes. Cellular and Molecular Life Sciences, 73(20), 3789–3800. https://doi.org/10.1007/s00018-016-2329-4
Makishima, M., Okamoto, A. Y., Repa, J. J., Tu, H., Learned, R. M., Luk, A., et al. (1999). Identification of a nuclear receptor for bile acids. Science, 284(5418), 1362–1365. https://doi.org/10.1126/science.284.5418.1362
Moore, L. B., Parks, D. J., Jones, S. A., Bledsoe, R. K., Consler, T. G., Stimmel, J. B., et al. (2000). Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. Journal of Biological Chemistry, 275(20), 15122–15127. https://doi.org/10.1074/jbc.M001215200
Chawla, A., Repa, J. J., Evans, R. M., & Mangelsdorf, D. J. (2001). Nuclear receptors and lipid physiology: Opening the X-files. Science, 294(5548), 1866–1870. https://doi.org/10.1126/science.294.5548.1866
Orth, D. N., Kovacs, W., & DeBold, C. R. (1998). Williams textbook of endocrinology. In Williams Textbook of Endocrinology. WB Saunders Co.
Sporn, M. B., Roberts, A. B., & Goodman, D. S. (1994). The retinoids: Biology, chemistry, and medicine (pp. 319). Lippincott Williams & Wilkins.
Thummel, C. S. (1995). From embryogenesis to metamorphosis: The regulation and function of Drosophila nuclear receptor superfamily members. Cell, 83(6), 871–877. https://doi.org/10.1016/0092-8674(95)90203-1
Jones, G., Strugnell, S. A., & DeLuca, H. F. (1998). Current understanding of the molecular actions of vitamin D. Physiological Reviews, 78(4), 1193–1231. https://doi.org/10.1152/physrev.1998.78.4.1193
Forrest, D., & Vennstrom, B. (2000). Functions of thyroid hormone receptors in mice. Thyroid, 10(1), 41–52. https://doi.org/10.1089/thy.2000.10.41
Germain, P., Staels, B., Dacquet, C., Spedding, M., & Laudet, V. (2006). Overview of nomenclature of nuclear receptors. Pharmacological Reviews, 58(4), 685–704.
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