A Rare Cutaneous Hamartomatous Adnexal Tumor: Trichofolliculoma

Adnexal Surgery – Case Report

Zekey E.a· Kurtipek G.S.b

Author affiliations

aDermatology, Sivas Numune Hospital, Sivas, Turkey
bDermatology, Selcuk University Medical School Hospital, Konya, Turkey

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Article / Publication Details

First-Page Preview

Abstract of Adnexal Surgery – Case Report

Received: August 10, 2022
Accepted: November 04, 2022
Published online: December 08, 2022

Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 0

ISSN: 2296-9195 (Print)
eISSN: 2296-9160 (Online)

For additional information: https://www.karger.com/SAD

Abstract

Introduction: Trichofolliculoma is a very rare, benign hamartomatous skin adnexal tumor originating from the hair follicle. The tumor which presents as a papule or nodule is usually observed on the scalp and face. Case Presentation: We report the case of a 49-year-old female who presented with a solitary papule on the nose. The lesion which was observed macroscopically and dermoscopically compatible with trichofolliculoma was completely removed by punch biopsy. The diagnosis of trichofolliculoma was confirmed histopathologically, and no recurrence was observed in the follow-up. Conclusion: Trichofolliculomas can macroscopically mimic some skin cancers such as basal cell carcinoma and sebaceous carcinoma. Awareness of its typical clinical and dermoscopic features facilitates diagnosis and prevents aggressive surgical intervention.

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References Gokalp H, Gurer MA, Alan S. Trichofolliculoma: a rare variant of hair follicle hamartoma. Dermatol Online J. 2013;19(8):19264. Singh N, Kumar N, Chandrashekar L, Thappa DM, Kar R, Srinivas BH. Umbilicated nodule over eyebrow. Dermatol Online J. 2013;19(9):19622. Kligman AM, Pinkus H. The histogenesis of nevoid tumors of the skin. Arch Dermatol. 1960;81(6):922–30. Gore HC, Jr. Trichofolliculoma. Arch Dermatol. 1964;89(3):385–6. Hyman AB, Clayman SJ. Hair-follicle nevus; report of a case and a review of the literature concerning this lesion and some related conditions. AMA Arch Derm. 1957;75(5):678–84. Ishii N, Kawaguchi H, Takahashi K, Nakajima H. A case of congenital trichofolliculoma. The J Dermatol. 1992;19(3):195–6. Gray HR, Helwig EB. Trichofolliculoma. Arch Dermatol. 1962;86(5):619–25. O'Mahony JJ. Trichofolliculoma of the external auditory meatus. Report of a case and a review of the literature. J Laryngol Otol. 1981;95(6):623–5. Morton AD, Nelson CC, Headington JT, Elner VM. Recurrent trichofolliculoma of the upper eyelid margin. Ophthalmic Plast Reconstr Surg. 1997;13(4):287–8. Taniguchi S, Hamada T. Trichofolliculoma of the eyelid. Eye. 1996;10(6):751–2. Mizutani H, Senga K, Ueda M. Trichofolliculoma of the upper lip: report of a case. Int J Oral Maxillofac Surg. 1999;28(2):135–6. Arias Palomo MD, Gutierrez Ortega MC, Hasson Nisis A, Martin Moreno L, Requena Caballero L, Barat Cascante A. [Intranasal trichofolliculoma]. Med Cutan Ibero Lat Am. 1990;18(3):159–61. Peterdy GA, Huettner PC, Rajaram V, Lind AC. Trichofolliculoma of the vulva associated with vulvar intraepithelial neoplasia: report of three cases and review of the literature. Int J Gynecol Pathol. 2002;21(3):224–30. Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, et al. Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia. Proc Natl Acad Sci U S A. 2014;111(28):10215–20. Garcia-Garcia SC, Villarreal-Martinez A, Guerrero-Gonzalez G, Miranda-Maldonado I, Ocampo-Candiani J. Dermoscopy of trichofolliculoma: a rare hair follicle hamartoma. J Eur Acad Dermatol Venereol. 2017;31(2):e123–e124. Misago N, Kimura T, Toda S, Mori T, Narisawa Y. A revaluation of trichofolliculoma: the histopathological and immunohistochemical features. Am J Dermatopathol. 2010;32(1):35–43. Mertens RB, de Peralta-Venturina MN, Balzer BL, Frishberg DP. GATA3 expression in normal skin and in benign and malignant epidermal and cutaneous adnexal neoplasms. Am J Dermatopathol. 2015;37(12):885–91. Romero-Pérez D, García-Bustinduy M, Cribier B. Clinicopathologic study of 90 cases of trichofolliculoma. J Eur Acad Dermatol Venereol. 2017;31(3):e141–e142. Kan L, Liu Y, McGuire TL, Bonaguidi MA, Kessler JA. Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias. J Biomed Sci. 2011;18(1):92. Stern JB, Stout DA. Trichofolliculoma showing perineural invasion. Trichofolliculocarcinoma? Arch Dermatol. 1979;115(8):1003–4. Ghosh SK, Bandyopadhyay D, Barma KD. Perifollicular nodule on the face of a young man. Indian J Dermatol Venereol Leprol. 2011;77(4):531–3. Article / Publication Details

First-Page Preview

Abstract of Adnexal Surgery – Case Report

Received: August 10, 2022
Accepted: November 04, 2022
Published online: December 08, 2022

Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 0

ISSN: 2296-9195 (Print)
eISSN: 2296-9160 (Online)

For additional information: https://www.karger.com/SAD

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