Einhorn, L. H. Treatment of testicular cancer: a new and improved model. J. Clin. Oncol. 8, 1777–1781 (1990).
Hanna, N. H. & Einhorn, L. H. Testicular cancer — discoveries and updates. N. Engl. J. Med. 371, 2005–2016 (2014).
Chovanec, M., Hanna, N., Cary, K. C., Einhorn, L. & Albany, C. Management of stage I testicular germ cell tumours. Nat. Rev. Urol. 13, 663–673 (2016).
Beyer, J. et al. Survival and new prognosticators in metastatic seminoma: results from the IGCCCG-update consortium. J. Clin. Oncol. 39, 1553–1562 (2021).
Gillessen, S. et al. Predicting outcomes in men with metastatic nonseminomatous germ cell tumors (NSGCT): results from the IGCCCG update consortium. J. Clin. Oncol. 39, 1563–1574 (2021).
Motzer, R. J. et al. Salvage chemotherapy for patients with germ cell tumors. The Memorial Sloan-Kettering Cancer Center experience (1979–1989). Cancer 67, 1305–1310 (1991).
Mardiak, J. et al. Paclitaxel plus ifosfamide and cisplatin in second-line treatment of germ cell tumors: a phase II study. Neoplasma 52, 497–501 (2005).
Motzer, R. J. Paclitaxel (Taxol) combination therapy for resistant germ cell tumors. Semin. Oncol. 27, 33–35 (2000).
Adra, N. et al. High-dose chemotherapy and autologous peripheral-blood stem-cell transplantation for relapsed metastatic germ cell tumors: the Indiana University experience. J. Clin. Oncol. 35, 1096–1102 (2017).
Feldman, D. R. et al. TI-CE high-dose chemotherapy for patients with previously treated germ cell tumors: results and prognostic factor analysis. J. Clin. Oncol. 28, 1706–1713 (2010).
Lorch, A. et al. Conventional-dose versus high-dose chemotherapy as first salvage treatment in male patients with metastatic germ cell tumors: evidence from a large international database. J. Clin. Oncol. 29, 2178–2184 (2011).
Li, M. C., Whitmore, W. F. Jr., Golbey, R. & Grabstald, H. Effects of combined drug therapy on metastatic cancer of the testis. JAMA 174, 1291–1299 (1960).
Hanna, N. & Einhorn, L. H. Testicular cancer — discoveries and updates. N. Engl. J. Med. 371, 2342 (2014).
Rosenberg, B., Vancamp, L. & Krigas, T. Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode. Nature 205, 698–699 (1965).
Higby, D. J., Wallace, H. J. Jr, Albert, D. J. & Holland, J. F. Diaminodichloroplatinum: a phase I study showing responses in testicular and other tumors. Cancer 33, 1219–1215 (1974).
Einhorn, L. H. & Donohue, J. Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. Ann. Intern. Med. 87, 293–298 (1977).
Einhorn, L. H. & Williams, S. D. Chemotherapy of disseminated testicular cancer. A random prospective study. Cancer 46, 1339–1344 (1980).
Einhorn, L. H., Williams, S. D., Troner, M., Birch, R. & Greco, F. A. The role of maintenance therapy in disseminated testicular cancer. N. Engl. J. Med. 305, 727–731 (1981).
Stoter, G. et al. High-dose versus low-dose vinblastine in cisplatin-vinblastine-bleomycin combination chemotherapy of non-seminomatous testicular cancer: a randomized study of the EORTC Genitourinary Tract Cancer Cooperative Group. J. Clin. Oncol. 4, 1199–1206 (1986).
Williams, S. D. et al. Treatment of disseminated germ-cell tumors with cisplatin, bleomycin, and either vinblastine or etoposide. N. Engl. J. Med. 316, 1435–1440 (1987).
Powis, G. Dose-dependent metabolism, therapeutic effect, and toxicity of anticancer drugs in man. Drug. Metab. Rev. 14, 1145–1163 (1983).
Bleyer, W. A. The clinical pharmacology of methotrexate: new applications of an old drug. Cancer 41, 36–51 (1978).
Creasey, W. A. et al. Clinical effects and pharmacokinetics of different dosage schedules of adriamycin. Cancer Res. 36, 216–221 (1976).
Hillcoat, B. L., McCulloch, P. B., Figueredo, A. T., Ehsan, M. H. & Rosenfeld, J. M. Clinical response and plasma levels of 5-fluorouracil in patients with colonic cancer treated by drug infusion. Br. J. Cancer 38, 719–724 (1978).
Ozols, R. F. et al. A randomized trial of standard chemotherapy v a high-dose chemotherapy regimen in the treatment of poor prognosis nonseminomatous germ-cell tumors. J. Clin. Oncol. 6, 1031–1040 (1988).
Miller, R. P., Tadagavadi, R. K., Ramesh, G. & Reeves, W. B. Mechanisms of cisplatin nephrotoxicity. Toxins 2, 2490–2518 (2010).
Blijham, G. et al. The treatment of advanced testicular carcinoma with high dose chemotherapy and autologous marrow support. Eur. J. Cancer 17, 433–441 (1981).
Mulder, P. O. et al. Chemotherapy with maximally tolerable doses of VP 16-213 and cyclophosphamide followed by autologous bone marrow transplantation for the treatment of relapsed or refractory germ cell tumors. Eur. J. Cancer Clin. Oncol. 24, 675–679 (1988).
Nichols, C. R. et al. Dose-intensive chemotherapy in refractory germ cell cancer — a phase I/II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation. J. Clin. Oncol. 7, 932–939 (1989).
Broun, E. R. et al. Long-term outcome of patients with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue. Ann. Intern. Med. 117, 124–128 (1992).
Einhorn, L. H. VP 16 plus ifosfamide plus cisplatin as salvage therapy in refractory testicular cancer. Cancer Chemother. Pharmacol. 18, S45–S50 (1986).
Harstrick, A. et al. Cisplatin, etoposide, and ifosfamide salvage therapy for refractory or relapsing germ cell carcinoma. J. Clin. Oncol. 9, 1549–1555 (1991).
Nichols, C. R. et al. High-dose carboplatin and etoposide with autologous bone marrow transplantation in refractory germ cell cancer: an Eastern Cooperative Oncology Group protocol. J. Clin. Oncol. 10, 558–563 (1992).
Ayash, L. J. et al. Double dose-intensive chemotherapy with autologous stem cell support for relapsed and refractory testicular cancer: the University of Michigan experience and literature review. Bone Marrow Transplant. 27, 939–947 (2001).
Einhorn, L. H. et al. High-dose chemotherapy and stem-cell rescue for metastatic germ-cell tumors. N. Engl. J. Med. 357, 340–348 (2007).
Motzer, R. J. et al. High-dose chemotherapy and autologous bone marrow rescue for patients with refractory germ cell tumors. Early intervention is better tolerated. Cancer 69, 550–556 (1992).
Pizzocaro, G. et al. Modified cisplatin, etoposide (or vinblastine) and ifosfamide salvage therapy for male germ-cell tumors. Long-term results. Ann. Oncol. 3, 211–216 (1992).
Vaena, D. A., Abonour, R. & Einhorn, L. H. Long-term survival after high-dose salvage chemotherapy for germ cell malignancies with adverse prognostic variables. J. Clin. Oncol. 21, 4100–4104 (2003).
Lorch, A. et al. High-dose chemotherapy (HDCT) as second-salvage treatment in patients with multiple relapsed or refractory germ-cell tumors. Ann. Oncol. 21, 820–825 (2010).
Siegert, W. et al. High-dose treatment with carboplatin, etoposide, and ifosfamide followed by autologous stem-cell transplantation in relapsed or refractory germ cell cancer: a phase I/II study. The German Testicular Cancer Cooperative Study Group. J. Clin. Oncol. 12, 1223–1231 (1994).
Beyer, J. et al. Long-term survival of patients with recurrent or refractory germ cell tumors after high dose chemotherapy. Cancer 79, 161–168 (1997).
Beyer, J., Stenning, S., Gerl, A., Fossa, S. & Siegert, W. High-dose versus conventional-dose chemotherapy as first-salvage treatment in patients with non-seminomatous germ-cell tumors: a matched-pair analysis. Ann. Oncol. 13, 599–605 (2002).
Motzer, R. J. et al. High-dose carboplatin, etoposide, and cyclophosphamide for patients with refractory germ cell tumors: treatment results and prognostic factors for survival and toxicity. J. Clin. Oncol. 14, 1098–1105 (1996).
Rick, O. et al. Salvage treatment with paclitaxel, ifosfamide, and cisplatin plus high-dose carboplatin, etoposide, and thiotepa followed by autologous stem-cell rescue in patients with relapsed or refractory germ cell cancer. J. Clin. Oncol. 19, 81–88 (2001).
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