Gueant JL. Homocysteine and related genetic polymorphisms in Down’s syndrome IQ. J Neurol Neurosurg Psychiatry. 2005;76(5):706–9.
Article PubMed PubMed Central Google Scholar
Baburamani AA, Patkee PA, Arichi T, Rutherford MA. New approaches to studying early brain development in Down syndrome. Dev Med Child Neurol. 2019;61(8):867–79.
Article PubMed PubMed Central Google Scholar
Lanfranchi S, Jerman O, Dal Pont E, Alberti A, Vianello R. Executive function in adolescents with Down syndrome: executive function in Down syndrome. J Intellect Disabil Res. 2010;54(4):308–19.
Article PubMed CAS Google Scholar
Vicari S, Bellucci S, Carlesimo GA. Visual and spatial long-term memory: differential pattern of impairments in Williams and Down syndromes. Dev Med Child Neurol. 2005;47(5):305–11.
Startin CM, Hamburg S, Hithersay R, Davies A, Rodger E, Aggarwal N, et al. The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome. Wellcome Open Res. 2016;15(1):11.
Lott IT, Dierssen M. Cognitive deficits and associated neurological complications in individuals with Down’s syndrome. Lancet Neurol. 2010;9(6):623–33.
Pinter JD, Eliez S, Schmitt JE, Capone GT, Reiss AL. Neuroanatomy of Down’s syndrome: a high-resolution MRI study. AJP. 2001;158(10):1659–65.
Pinter JD, Brown WE, Eliez S, Schmitt JE, Capone GT, Reiss AL. Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study. Neurology. 2001;56(7):972–4.
Article PubMed CAS Google Scholar
Guidi S, Bonasoni P, Ceccarelli C, Santini D, Gualtieri F, Ciani E, et al. Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome: hippocampal hypocellularity in down fetuses. Brain Pathol. 2007;18(2):180–97.
Article PubMed PubMed Central Google Scholar
Guidi S, Ciani E, Bonasoni P, Santini D, Bartesaghi R. Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with Down syndrome: down syndrome fetal cerebellum. Brain Pathol. 2011;21(4):361–73.
Utagawa EC, Moreno DG, Schafernak KT, Arva NC, Malek-Ahmadi MH, Mufson EJ, et al. Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome. Acta Neuropathol Commun. 2022;10(1):86.
Article PubMed PubMed Central CAS Google Scholar
Petit TL, LeBoutillier JC, Alfano DP, Becker LE. Synaptic development in the human fetus: a morphometric analysis of normal and Down’s syndrome neocortex. Exp Neurol. 1984;83(1):13–23.
Article PubMed CAS Google Scholar
Becker LE, Armstrong DL, Chan F. Dendritic atrophy in children with Down’s syndrome. Ann Neurol. 1986;20(4):520–6.
Article PubMed CAS Google Scholar
Takashima S, Ieshima A, Nakamura H, Becker LE. Dendrites, dementia and the Down syndrome. Brain Dev. 1989;11(2):131–3.
Article PubMed CAS Google Scholar
Contestabile A, Fila T, Ceccarelli C, Bonasoni P, Bonapace L, Santini D, et al. Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with down syndrome and in Ts65Dn mice. Hippocampus. 2007;17(8):665–78.
Golden JA, Hyman BT. Development of the superior temporal neocortex is anomalous in trisomy 21. J Neuropathol Exp Neurol. 1994;53(5):513–20.
Article PubMed CAS Google Scholar
Becker W, Joost HG. Structural and Functional characteristics of dyrk, a novel subfamily of protein kinases with dual specificity. Prog Nucleic Acid Res Mol Biol. 1999;62:1–17.
Shen X, Liu Y, Hsu YJ, Fujiwara Y, Kim J, Mao X, et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell. 2008;32(4):491–502.
Article PubMed PubMed Central CAS Google Scholar
Yang EJ, Ahn YS, Chung KC. Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells. J Biol Chem. 2001;276(43):39819–24.
Article PubMed CAS Google Scholar
Lepagnol-Bestel AM, Zvara A, Maussion G, Quignon F, Ngimbous B, Ramoz N, et al. DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome. Hum Mol Genet. 2009;18(8):1405–14.
Article PubMed CAS Google Scholar
Li S, Xu C, Fu Y, Lei PJ, Yao Y, Yang W, et al. DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers. Nucleic Acids Res. 2018;46(21):11202–13.
Article PubMed PubMed Central CAS Google Scholar
Jayaraman G, Srinivas R, Duggan C, Ferreira E, Swaminathan S, Somasundaram K, et al. p300/cAMP-responsive element-binding protein interactions with Ets-1 and Ets-2 in the transcriptional activation of the human stromelysin promoter. J Biol Chem. 1999;274(24):17342–52.
Article PubMed CAS Google Scholar
Sun HJ, Xu X, Wang XL, Wei L, Li F, Lu J, et al. Transcription factors Ets2 and Sp1 Act synergistically with histone acetyltransferase p300 in activating human interleukin-12 p40 promoter. ABBS. 2006;38(3):194–200.
Article PubMed CAS Google Scholar
Graves BJ, Petersen JM. Specificity within the ets family of transcription factors. Adv Cancer Res. 1998;75:1–55.
Article PubMed CAS Google Scholar
Tymms MJ, Kola I. Regulation of gene expression by transcription factors Ets-1 and Ets-2. Mol Reprod Dev. 1994;39(2):208–14.
Article PubMed CAS Google Scholar
Seth A, Watson DK, Blair DG, Papas TS. c-ets-2 protooncogene has mitogenic and oncogenic activity. Proc Natl Acad Sci USA. 1989;86(20):7833–7.
Article PubMed PubMed Central CAS Google Scholar
Sevilla L, Aperlo C, Dulic V, Chambard JC, Boutonnet C, Pasquier O, et al. The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Mol Cell Biol. 1999;19(4):2624–34.
Article PubMed PubMed Central CAS Google Scholar
Watson DK, Robinson L, Hodge DR, Kola I, Papas TS, Seth A. FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements. Oncogene. 1997;14(2):213–21.
Article PubMed CAS Google Scholar
Wolvetang EJ. ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway. Hum Mol Genet. 2003;12(3):247–55.
Article PubMed CAS Google Scholar
Heru Sumarsono S, Wilson TJ, Tymms MJ, Venter DJ, Corrick CM, Kola R, et al. Down’s syndrome-like skeletal abnormalities in Ets2 transgenic mice. Nature. 1996;379(6565):534–7.
Huang H, Rambaldi I, Daniels E, Featherstone M. Expression of theWdr9 gene and protein products during mouse development. Dev Dyn. 2003;227(4):608–14.
Article PubMed CAS Google Scholar
Mandal M, Hamel KM, Maienschein-Cline M, Tanaka A, Teng G, Tuteja JH, et al. Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015;16(10):1094–103.
Article PubMed PubMed Central CAS Google Scholar
Mandal M, Maienschein-Cline M, Maffucci P, Veselits M, Kennedy DE, McLean KC, et al. BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis. Nat Commun. 2018;9(1):3888.
Article PubMed PubMed Central Google Scholar
Kagoshima H, Shigesada K, Satake M, Ito Y, Miyoshi H, Ohki M, et al. The runt domain identifies a new family of heterometric transcriptional regulators. Trends Genet. 1993;9(10):338–41.
Article PubMed CAS Google Scholar
Kitabayashi I. Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation. EMBO J. 1998;17(11):2994–3004.
Article PubMed PubMed Central CAS Google Scholar
Oakford PC, James SR, Qadi A, West AC, Ray SN, Bert AG, et al. Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1. Leuk Res. 2010;34(9):1203–13.
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