Becker T, Anliker B, Becker CG, Taylor J, Schachner M, Meyer RL, et al. Tenascin-R inhibits regrowth of optic fibers in vitro and persists in the optic nerve of mice after injury. Glia. 2000;29:330–4.

Article  CAS  Google Scholar 

Fawcett JW, Asher RA. The glial scar and central nervous system repair. Brain Res Bull. 1999;49:377–91.

Article  CAS  Google Scholar 

McKerracher L, David S, Jackson DL, Kottis V, Dunn RJ, Braun PE. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron. 1994;13:805–11.

Article  CAS  Google Scholar 

Merkler D, Metz GA, Raineteau O, Dietz V, Schwab ME, Fouad K. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin associated neurite growth inhibitor Nogo-A. J Neurosci. 2001;21:3665–73.

Article  CAS  Google Scholar 

Schnell L, Schwab ME. Axonal degeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature. 1990;343:269–72.

Article  CAS  Google Scholar 

Skene JH. Axonal growth-associated proteins. Annu Rev Neurosci. 1989;12:127–56.

Article  CAS  Google Scholar 

Widenfalk J, Lundstromer K, Jubran M, Brene S, Olson L. Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid. J Neurosci. 2001;21:3457–75.

Article  CAS  Google Scholar 

Schwartz M. Autoimmune involvement in CNS trauma is beneficial if well controlled. Prog Brain Res. 2000;128:259–63.

Article  CAS  Google Scholar 

McCreedy DA, Sakiyama-Elbert SE. Combination therapies in the CNS: engineering the environment. Neurosci Lett. 2012;519:115–21.

Article  CAS  Google Scholar 

Akiyama Y, Radtke C, Honmou O, Kocsis JD. Remyelination of the spinal cord following intravenous delivery of bone marrow cells. Glia. 2002;39:229–36.

Article  Google Scholar 

Chopp M, Zhang XH, Li Y, Wang L, Chen J, Lu D. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. NeuroReport. 2000;11:3001–5.

Article  CAS  Google Scholar 

Parr AM, Kulbatski I, Tator CH. Transplantation of adult rat spinal cord stem/progenitor cells for spinal cord injury. J Neurotrauma. 2007;24:835–45.

Article  Google Scholar 

Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143–7.

Article  CAS  Google Scholar 

Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G, et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science. 1998;279:1528–30.

Article  CAS  Google Scholar 

Orlic D, Kajstura J, Chimenti S, Bodine DM, Leri A, Anversa P. Transplanted adult bone marrow cells repair myocardial infarcts in mice. Ann N Y Acad Sci. 2001;938:221–9.

Article  CAS  Google Scholar 

Kohyama J, Abe H, Shimazaki T, Koizumi A, Okano H, Hata J, et al. Brain from bone: efficient “meta-differentiation” of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation. 2001;68:235–44.

Article  CAS  Google Scholar 

Sanchez-Ramos J, Song S, Cardozo-Pelaez F, Hazzi C, Stedeford T, Willing A, et al. Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol. 2000;164:247–56.

Article  CAS  Google Scholar 

Kumar M, Yasotha T, Singh RK, Singh R, Kumar K, Ranjan R, et al. Generation of transgenic mesenchymal stem cells expressing green fluorescent protein as reporter gene using no viral vector in caprine. Indian J Exp Biol. 2013;51:502–9.

CAS  Google Scholar 

Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res. 2000;61:364–70.

Article  CAS  Google Scholar 

Basso DM, Beattie MS, Bresnahan JC, Anderson DK, Faden AI, Gruner JA, et al. MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study. J Neurotrauma. 1996;13:343–59.

Article  CAS  Google Scholar 

Tarlov IM. Spinal cord compression: mechanism of paralysis and treatment. Springfield, Ill: Charles C. Thomas. 1957; p 147

Olby N, Harris T, Burr J, Munana K, Sharp N, Keene B. Recovery of pelvic limb function in dogs following acute intervertebral disc herniations. J Neurotrauma. 2004;21:49–59.

Article  Google Scholar 

Kim JW, Ha KY, Molon JN, Kim YH. Bone marrow-derived mesenchymal stem cell transplantation for chronic spinal cord injury in rats: comparative study between intralesional and intravenous transplantation. Spine. 2013;38:E1065–74.

Article  Google Scholar 

Mothe AJ, Bozkurt G, Catapano J, Zabojova J, Wang X, Keating A, et al. Intrathecal transplantation of stem cells by lumbar puncture for thoracic spinal cord injury in the rat. Spinal Cord. 2011;49:967–73.

Article  CAS  Google Scholar 

Cizkova D, Novotna I, Slovinska L, Vanicky I, Jergova S, Rosocha J, et al. Repetitive intrathecal catheter delivery of bone marrow mesenchymal stromal cells improves functional recovery in a rat model of contusive spinal cord injury. J Neurotrauma. 2011;28:1951–62.

Article  Google Scholar 

Bakshi A, Barshinger AL, Swanger SA, Madhavani V, Shumsky JS, Neuhuber B, et al. Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation. J Neurotrauma. 2006;23:55–65.

Article  Google Scholar 

Takahashi Y, Tsuji O, Kumagai G, Hara CM, Okano HJ, Miyawaki A, et al. Comparative study of methods for administering neural stem/progenitor cells to treat spinal cord injury in mice. Cell Transplant. 2010;20:727–39.

Article  Google Scholar 

Mansilla E, Marin GH, Sturla F, Drago HE, Gil MA, Salas E, et al. Human mesenchymal stem cells are tolerized by mice and improve skin and spinal cord injuries. Transplant Proc. 2005;37:292–4.

Article  CAS  Google Scholar 

Wu J, Feng D, Yang T. Effect of transplanting marrow mesenchymal stem cells via subarachnoid space on spinal cord injury and T cell subpopulation in rats. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007;21:492–6.

CAS  Google Scholar 

Bakshi A, Hunter C, Swanger S, Lepore A, Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique. J Neurosurg. (Spine 1) 2004;3:330–7.

Chen Q, Long Y, Yuan X, Zou L, Sun J, Chen S, et al. Protective effects of bone marrow stromal cell transplantation in injured rodent brain: synthesis of neurotrophic factors. J Neurosci Res. 2005;80:611–9.

Article  CAS  Google Scholar 

Rosenzweig ES, McDonald JW. Rodent models for treatment of spinal cord injury: research trends and progress toward useful repair. Curr Opin Neurol. 2004;17:121–31.

Article  Google Scholar 

Carvalho KA, Vialle EN, Moreira GH, Cunha RC, Simeoni RB, Francisco JC, et al. Functional outcome of bone marrow stem cells (CD45(+)/CD34(-)) after cell therapy in chronic spinal cord injury in Wistar rats. Transplant Proc. 2008;40:845–6.

Article  CAS  Google Scholar