English et al., 2010 [25]American menPCBPRetrospective1783NoCYP2C8rs1934951NRPlasmaArachidonic acid metabolismBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019, Zhong et al., 2013Such et al., 2011 [26]Spanish, GreekMMBPRetrospective4237165CYP2C8rs193495184 (10–256)Peripheral blood or serumArachidonic acid metabolismBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019, Zhong et al., 2013Katz et al., 2011 [48]AmericanMMBPRetrospective1266NoCOL1A1, MMP2,
RANK, OPG, OPN, TNF, CYP2C810 SNPsNRBloodRelated to osteoporosis, bone mineral density, osteoclastogenesis, bone resorptionBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Arduino et al., 2011 [49]Italian femalesBC, MMBPRetrospective3030125VEGFrs3025039
rs699947
rs2010963NRPeripheral venous bloodAngiogenesisBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Di Martino et al., 2011 [50]ItalianMMBPRetrospective910NoPPARGrs1152003NRPeripheral bloodInvolved in adipocyte differentiation and angiogenesisBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Marini et al., 2011 [51]ItalianMM, BC, PCBPRetrospective3434NoFDPSrs2297480NRPeripheral bloodCholesterol metabolismBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019, Zhong et al., 2013Balla et al., 2012 [52]HungarianMM, OP, BC, PC, RC, CCBPRetrospective46No224CYP2C8rs1934951NRBloodArachidonic acid metabolismBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019, Zhong et al., 2013La Ferla et al., 2012 [53]ItalianMM, BC, PCBPRetrospective3053NoER
CYP19A1rs2234693
rs9340799
rs10046NRPeripheral venous bloodFundamental role in osteoclast function and angiogenesisBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Stockmann et al., 2013 [54]GermanMM, BC, PCBPRetrospective94110NoHLA-DRB1
HLA-DQB1Multiple gene locus34 (11–41)BloodOsteoimmunology metabolismBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Choi et al., 2015 [55]South KoreanOP, RABPRetrospective2619NoVEGFrs3025039
rs699947
rs2010963NRSalivaAngiogenesisBastida-Lertxund et al., 2019, Guo et al., 2019, Sandro Pereira da Silva et al., 2019, Yang et al., 2019Kastritis et al., 2017 [56]GreekMMBPRetrospective36104NoCYP2C8
PPARGrs1934951
rs115200357Peripheral bloodAngiogenesis and bone remodellingBastida-Lertxund et al., 2019, Guo et al., 2019, Yang et al., 2019