Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49. https://doi.org/10.3322/caac.21660.
Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72:7–33. https://doi.org/10.3322/caac.21708.
Sanger HL, Klotz G, Riesner D, Gross HJ, Kleinschmidt AK. Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc Natl Acad Sci U S A. 1976;73:3852–6. https://doi.org/10.1073/pnas.73.11.3852.
Article PubMed CAS PubMed Central Google Scholar
Cocquerelle C, Mascrez B, Hétuin D, Bailleul B. Mis-splicing yields circular RNA molecules. FASEB J. 1993;7:155–60. https://doi.org/10.1096/fasebj.7.1.7678559.
Article PubMed CAS Google Scholar
Liu Z, Zhou Y, Liang G, Ling Y, Tan W, Tan L, et al. Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death Dis. 2019;10:55. https://doi.org/10.1038/s41419-018-1287-1.
Article PubMed CAS PubMed Central Google Scholar
Cao L, Wang M, Dong Y, Xu B, Chen J, Ding Y, et al. Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2. Cell Death Dis. 2020;11:145. https://doi.org/10.1038/s41419-020-2336-0.
Article PubMed CAS PubMed Central Google Scholar
Liu Y, Chen S, Zong ZH, Guan X, Zhao Y. CircRNA WHSC1 targets the miR-646/NPM1 pathway to promote the development of endometrial cancer. J Cell Mol Med. 2020;24:6898–907. https://doi.org/10.1111/jcmm.15346.
Article PubMed CAS PubMed Central Google Scholar
Chen RX, Liu HL, Yang LL, Kang FH, Xin LP, Huang LR, et al. Circular RNA circRNA_0000285 promotes cervical cancer development by regulating FUS. Eur Rev Med Pharmacol Sci. 2019;23:8771–8. https://doi.org/10.26355/eurrev_201910_19271.
Wang J, Zhao X, Wang Y, Ren F, Sun D, Yan Y, et al. circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma. Cell Death Dis. 2020;11:32. https://doi.org/10.1038/s41419-020-2230-9.
Article PubMed CAS PubMed Central Google Scholar
Huang G, Liang M, Liu H, Huang J, Li P, Wang C, et al. CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway. Cell Death Dis. 2020;11:1065. https://doi.org/10.1038/s41419-020-03276-1.
Article PubMed CAS PubMed Central Google Scholar
Liu J, Xue N, Guo Y, Niu K, Gao L, Zhang S, et al. CircRNA_100367 regulated the radiation sensitivity of esophageal squamous cell carcinomas through miR-217/Wnt3 pathway. Aging (Albany NY). 2019;11:12412–27. https://doi.org/10.18632/aging.102580.
Article PubMed CAS Google Scholar
Yang H, Li X, Meng Q, Sun H, Wu S, Hu W, et al. CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer. Mol Cancer. 2020;19:13. https://doi.org/10.1186/s12943-020-1139-3.
Article PubMed CAS PubMed Central Google Scholar
Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, et al. Circular RNAs are abundant, conserved, and associated with ALU repeats. Rna. 2013;19:141–57. https://doi.org/10.1261/rna.035667.112.
Article PubMed CAS PubMed Central Google Scholar
Ashwal-Fluss R, Meyer M, Pamudurti NR, Ivanov A, Bartok O, Hanan M, et al. circRNA biogenesis competes with pre-mRNA splicing. Mol Cell. 2014;56:55–66. https://doi.org/10.1016/j.molcel.2014.08.019.
Article PubMed CAS Google Scholar
Li X, Yang L, Chen LL. The biogenesis, functions, and challenges of circular RNAs. Mol Cell. 2018;71:428–42. https://doi.org/10.1016/j.molcel.2018.06.034.
Article PubMed CAS Google Scholar
Zaiou M. Circular RNAs as potential biomarkers and therapeutic targets for metabolic diseases. Adv Exp Med Biol. 2019;1134:177–91. https://doi.org/10.1007/978-3-030-12668-1_10.
Article PubMed CAS Google Scholar
Tagawa T, Gao S, Koparde VN, Gonzalez M, Spouge JL, Serquiña AP, et al. Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA. Proc Natl Acad Sci U S A. 2018;115:12805–10. https://doi.org/10.1073/pnas.1816183115.
Article PubMed CAS PubMed Central Google Scholar
Qiao Y, Zhao X, Liu J, Yang W. Epstein-Barr virus circRNAome as host miRNA sponge regulates virus infection, cell cycle, and oncogenesis. Bioengineered. 2019;10:593–603. https://doi.org/10.1080/21655979.2019.1679698.
Article PubMed CAS PubMed Central Google Scholar
Schmidt CA, Giusto JD, Bao A, Hopper AK, Matera AG. Molecular determinants of metazoan tricRNA biogenesis. Nucleic Acids Res. 2019;47:6452–65. https://doi.org/10.1093/nar/gkz311.
Article PubMed CAS PubMed Central Google Scholar
Li R, Jiang J, Shi H, Qian H, Zhang X, Xu W. CircRNA: a rising star in gastric cancer. Cell Mol Life Sci. 2020;77:1661–80. https://doi.org/10.1007/s00018-019-03345-5.
Article PubMed CAS Google Scholar
Li HM, Ma XL, Li HG. Intriguing circles: conflicts and controversies in circular RNA research. Wiley Interdiscip Rev RNA. 2019;10:e1538. https://doi.org/10.1002/wrna.1538.
Vincent HA, Deutscher MP. Substrate recognition and catalysis by the exoribonuclease RNase R. J Biol Chem. 2006;281:29769–75. https://doi.org/10.1074/jbc.M606744200.
Article PubMed CAS Google Scholar
Kristensen LS, Andersen MS, Stagsted LVW, Ebbesen KK, Hansen TB, Kjems J. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20:675–91. https://doi.org/10.1038/s41576-019-0158-7.
Article PubMed CAS Google Scholar
Huang A, Zheng H, Wu Z, Chen M, Huang Y. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020;10:3503–17. https://doi.org/10.7150/thno.42174.
Article PubMed CAS PubMed Central Google Scholar
Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 2013;495:333–8. https://doi.org/10.1038/nature11928.
Article PubMed CAS Google Scholar
Yang W, Li Y, Song X, Xu J, Xie J. Genome-wide analysis of long noncoding RNA and mRNA co-expression profile in intrahepatic cholangiocarcinoma tissue by RNA sequencing. Oncotarget. 2017;8:26591–9. https://doi.org/10.18632/oncotarget.15721.
Article PubMed PubMed Central Google Scholar
Wang PL, Bao Y, Yee MC, Barrett SP, Hogan GJ, Olsen MN, et al. Circular RNA is expressed across the eukaryotic tree of life. PLoS One. 2014;9:e90859. https://doi.org/10.1371/journal.pone.0090859.
Article PubMed CAS PubMed Central Google Scholar
Rybak-Wolf A, Stottmeister C, Glažar P, Jens M, Pino N, Giusti S, et al. Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed. Mol Cell. 2015;58:870–85. https://doi.org/10.1016/j.molcel.2015.03.027.
Article PubMed CAS Google Scholar
Wang Y, Liu J, Ma J, Sun T, Zhou Q, Wang W, et al. Exosomal circRNAs: biogenesis, effect and application in human diseases. Mol Cancer. 2019;18:116. https://doi.org/10.1186/s12943-019-1041-z.
Article PubMed CAS PubMed Central Google Scholar
Boriachek K, Islam MN, Möller A, Salomon C, Nguyen NT, Hossain MSA, et al. Biological functions and current advances in isolation and detection strategies for exosome nanovesicles. Small. 2018:14. https://doi.org/10.1002/smll.201702153.
Yan Y, Fu G, Ye Y, Ming L. Exosomes participate in the carcinogenesis and the malignant behavior of gastric cancer. Scand J Gastroenterol. 2017;52:499–504. https://doi.org/10.1080/00365521.2016.1278458.
Article PubMed CAS Google Scholar
Zeng K, He B, Yang BB, Xu T, Chen X, Xu M, et al. The pro-metastasis effect of circANKS1B in breast cancer. Mol Cancer. 2018;17:160. https://doi.org/10.1186/s12943-018-0914-x.
Article PubMed CAS PubMed Central Google Scholar
Yang R, Xing L, Zheng X, Sun Y, Wang X, Chen J. The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression. Mol Cancer. 2019;18:4. https://doi.org/10.1186/s12943-018-0933-7.
Article PubMed PubMed Central Google Scholar
Wang X, Ji C, Hu J, Deng X, Zheng W, Yu Y, et al. Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway. J Exp Clin Cancer Res. 2021;40:29. https://doi.org/10.1186/s13046-021-01830-z.
留言 (0)