Outpatient Treatment of Confirmed COVID-19: Living, Rapid Practice Points From the American College of Physicians (Version 1)

Affiliations:

American College of Physicians, Philadelphia, Pennsylvania (A.Q.)

American College of Physicians, Philadelphia, and Villanova University, Villanova, Pennsylvania (J.Y.)

Penn Medicine, Philadelphia, Pennsylvania (M.C.M., M.A.F.)

University of Connecticut, Mansfield, Connecticut (R.A.)

University of Illinois College of Medicine at Urbana-Champaign, Champaign, Illinois (J.A.J.)

University of Massachusetts Medical School and Saint Vincent Hospital, Worcester, Massachusetts (G.M.A.)

Portland Veterans Affairs Medical Center and Oregon Health & Science University, Portland, Oregon (L.L.H.)

Note: The practice points are meant to guide care based on the best available evidence and may not apply to all patients or individual clinical situations. They should not be used as a replacement for a clinician's judgment. Any reference to a product or process contained in a practice point is not intended as an endorsement of any specific commercial product. All practice points are considered automatically withdrawn or invalid 5 years after publication, or once an update has been issued.

Financial Support: Financial support for the development of the practice points comes exclusively from the ACP operating budget.

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M22-2249. All financial and intellectual disclosures of interest were declared, and potential conflicts were discussed and managed. Drs. Akl, Dunn, Kansagara, Marcucci, and Obley were recused from authorship and voting due to moderate-level conflicts of interest (recently authored relevant publications). A record of disclosures of interest and management of conflicts is kept for each SMPC meeting and conference call and can be viewed at www.acponline.org/about-acp/who-we-are/leadership/boards-committees-councils/scientific-medical-policy-committee/disclosure-of-interests-and-conflict-of-interest-management-summary-for-scientific-medical-policy.

Corresponding Author: Amir Qaseem, MD, PhD, MHA, American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106; e-mail, .

Author Contributions: Conception and design: I. Etxeandia-Ikobaltzeta, M.A. Forciea, J.A. Jokela, A. Qaseem, M.P. Tschanz, J. Yost.

Analysis and interpretation of the data: M.A. Forciea, C. Harrod, L.L. Humphrey, J.A. Jokela, A. Qaseem, T. Shamliyan, M.P. Tschanz, K. Umana, J. Yost.

Drafting of the article: G.M. Abraham, I. Etxeandia-Ikobaltzeta, J.A. Jokela, R.A. Lee, M.C. Miller, A. Qaseem, T. Shamliyan, M.P. Tschanz, J. Yost.

Critical revision for important intellectual content: G.M. Abraham, R. Andrews, I. Etxeandia-Ikobaltzeta, M.A. Forciea, C. Harrod, L.L. Humphrey, J.A. Jokela, R.A. Lee, A. Qaseem, T. Shamliyan, M.P. Tschanz, J. Yost.

Final approval of the article: G.M. Abraham, R. Andrews, I. Etxeandia-Ikobaltzeta, M.A. Forciea, C. Harrod, L.L. Humphrey, J.A. Jokela, R.A. Lee, M.C. Miller, A. Qaseem, T. Shamliyan, M.P. Tschanz, K. Umana, J. Yost.

Statistical expertise: C. Harrod, A. Qaseem, J. Yost.

Administrative, technical, or logistic support: A. Qaseem, T. Shamliyan, K. Umana, J. Yost.

Collection and assembly of data: J. Yost.

This article was published at Annals.org on 29 November 2022.

* This paper, authored by Amir Qaseem, MD, PhD, MHA; Jennifer Yost, PhD, RN; Matthew C. Miller, MD; Rebecca Andrews, MD, MS; Janet A. Jokela, MD, MPH; Mary Ann Forciea, MD; George M. Abraham, MD, MPH; and Linda L. Humphrey, MD, MPH, was developed for the Scientific Medical Policy Committee of the American College of Physicians. Individuals who served on the Scientific Medical Policy Committee from initiation of the project until its approval were Linda L. Humphrey, MD, MPH† (Chair); Adam Jacob Obley, MD‡ (Vice Chair); Elie A. Akl, MD, MPH, PhD‡; Rebecca Andrews, MD, MS†; Andrew Dunn, MD, MPH‡; Mary Ann Forciea, MD†; Ray Haeme‡§; Janet A. Jokela, MD, MPH†; Devan L. Kansagara, MD, MCR‡; Rachael A. Lee, MD, MSPH†; Maura Marcucci, MD, MSc‡; Matthew C. Miller, MD†; and CDR Mark P. Tschanz, DO†. Itziar Etxeandia-Ikobaltzeta, PharmD, PhD; Curtis Harrod, PhD, MPH; Tatyana Shamliyan, MD, MS; and Karla Umana, MPH, were authors from ACP staff. Kate Carroll, MPH, was a nonauthor contributor from ACP staff. Approved by the ACP Executive Committee of the Board of Regents on behalf of the Board of Regents on 22 July 2022.

† Author (participated in discussion and voting).

‡ Nonauthor contributor (participated in discussion but excluded from voting).

§ Nonphysician public representative.

Update Alerts: These practice points are based on a literature search through 4 April 2022. There is a plan for monthly literature surveillance, and the living, rapid review along with the practice points will be periodically updated.

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