Cen M, Ouyang W, Zhang W, Yang L, Lin X, Dai M, et al. MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism. Redox Biol. 2021;41:101936.
Article CAS PubMed PubMed Central Google Scholar
Li W, Long L, Yang X, Tong Z, Southwood M, King R, et al. Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice. Am J Respir Crit Care Med. 2021;203(11):1419–30.
Article CAS PubMed PubMed Central Google Scholar
McVey MJ, Steinberg BE, Goldenberg NM. Inflammasome activation in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2021;320(2):L165-l178.
Article CAS PubMed Google Scholar
Zhang H, Cui Y, Zhou Z, Ding Y, Nie H. Alveolar type 2 epithelial cells as potential therapeutics for acute lung injury/acute respiratory distress syndrome. Curr Pharm Des. 2019;25(46):4877–82.
Article CAS PubMed Google Scholar
Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315(8):788–800.
Article CAS PubMed Google Scholar
He YQ, Zhou CC, Yu LY, Wang L, Deng JL, Tao YL, et al. Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms. Pharmacol Res. 2021;163:105224.
Article CAS PubMed Google Scholar
Yu WY, Gao CX, Zhang HH, Wu YG, Yu CH. Herbal active ingredients: potential for the prevention and treatment of acute lung injury. Biomed Res Int. 2021;2021:5543185.
Article PubMed PubMed Central Google Scholar
Li N, Cao L, Cheng Y, Meng ZQ, Tang ZH, Liu WJ, et al. In vivo anti-inflammatory and analgesic activities of strictosamide from Nauclea officinalis. Pharm Biol. 2014;52(11):1445–50.
Article CAS PubMed Google Scholar
Song LL, Mu YL, Zhang HC, Wu GY, Sun JY. A new indole alkaloid with anti-inflammatory from the branches of Nauclea officinalis. Nat Prod Res. 2020;34(16):2283–8.
Article CAS PubMed Google Scholar
Song S, Liu P, Wang L, Li D, Fan H, Chen D, et al. In vitro anti-inflammatory activities of naucleoffieine H as a natural alkaloid from Nauclea officinalis Pierrc ex Pitard, through inhibition of the iNOS pathway in LPS-activated RAW 264.7 macrophages. Nat Prod Res. 2020;34(18):2694–7.
Article CAS PubMed Google Scholar
Mai SY, Li YH, Zhang XG, Wang YR, Zhang JQ, Jia A. A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis. Nat Prod Res. 2021;35(18):3049–55.
Article CAS PubMed Google Scholar
Bauermeister A, Mannochio-Russo H, Costa-Lotufo LV, Jarmusch AK, Dorrestein PC. Mass spectrometry-based metabolomics in microbiome investigations. Nat Rev Microbiol. 2022;20(3):143–60.
Article CAS PubMed Google Scholar
Marchev AS, Vasileva LV, Amirova KM, Savova MS, Balcheva-Sivenova ZP, Georgiev MI. Metabolomics and health: from nutritional crops and plant-based pharmaceuticals to profiling of human biofluids. Cell Mol Life Sci CMLS. 2021;78(19–20):6487–503.
Article CAS PubMed Google Scholar
Wang T, Lin S, Liu R, Li H, Liu Z, Zhang X, et al. Metabolomic profile perturbations of serum, lung, bronchoalveolar lavage fluid, spleen and feces in LPS-induced acute lung injury rats based on HPLC-ESI-QTOF-MS. Anal Bioanal Chem. 2020;412(5):1215–34.
Article CAS PubMed Google Scholar
Ding Z, Zhong R, Yang Y, Xia T, Wang W, Wang Y, et al. Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: a novel strategy for exploring active components and effective mechanism of TCM formulae. Pharmacol Res. 2020;156:104759.
Article CAS PubMed Google Scholar
Fu C, Wu Q, Zhang Z, Xia Z, Ji H, Lu H, et al. UPLC-ESI-IT-TOF-MS metabolomic study of the therapeutic effect of Xuefu Zhuyu decoction on rats with traumatic brain injury. J Ethnopharmacol. 2019;245:112149.
Article CAS PubMed Google Scholar
Wang ZY, Wang X, Zhang DY, Hu YJ, Li S. [Traditional Chinese medicine network pharmacology: development in new era under guidance of network pharmacology evaluation method guidance]. Zhongguo Zhong Yao Za Zhi. 2022;47(1):7–17.
Lai X, Wang X, Hu Y, Su S, Li W, Li S. Editorial: network pharmacology and traditional medicine. Front Pharmacol. 2020;11:1194.
Article PubMed PubMed Central Google Scholar
Chen W, Si Y, Cheng J, Ding J, Zhao H, Liu W, et al. Metabolic and Network Pharmacological Analyses of the Therapeutic Effect of Grona styracifolia on Calcium Oxalate-Induced Renal Injury. Front Pharmacol. 2021;12:652989.
Article CAS PubMed PubMed Central Google Scholar
Ding Q, Zhu W, Diao Y, Xu G, Wang L, Qu S, et al. Elucidation of the mechanism of action of ginseng against acute lung injury/acute respiratory distress syndrome by a network pharmacology-based strategy. Front Pharmacol. 2020;11:611794.
Article CAS PubMed Google Scholar
Jia L, Zhou H, Li W, Lv Z. Network pharmacology integrated molecular docking revealed the mechanism of Jianpi Yiqi Taohua decoction against ulcerative colitis. Med Sci Monit. 2022;28:e933537.
CAS PubMed PubMed Central Google Scholar
Hu L, Wang Y, Sun H, Xiong Y, Zhong L, Wu Z, et al. An untargeted metabolomics approach to investigate the wine-processed mechanism of Scutellariae radix in acute lung injury. J Ethnopharmacol. 2020;253:112665.
Article CAS PubMed Google Scholar
Cui Y, Liu S, Zhang X, Ding X, Duan X, Zhu Z, et al. Metabolomic analysis of the effects of adipose-derived mesenchymal stem cell treatment on rats with sepsis-induced acute lung injury. Front Pharmacol. 2020;11:902.
Article CAS PubMed PubMed Central Google Scholar
Zhang N, Lu F, Li Z, Zhao H, Pang M, Ye T, et al. Effects of Radix Scrophulariae on Hyperthyroidism Assessed by Metabonomics and Network Pharmacology. Front Pharmacol. 2021;12:727735.
Guo W, Liu S, Zheng X, Xiao Z, Chen H, Sun L, et al. Network Pharmacology/Metabolomics-Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of Mitochondrial Dysfunction in Cancer-Related Fatigue. Oxid Med Cell Longev. 2021;2021:5556212.
Article PubMed PubMed Central Google Scholar
Li T, Zhang W, Hu E, Sun Z, Li P, Yu Z, et al. Integrated metabolomics and network pharmacology to reveal the mechanisms of hydroxysafflor yellow A against acute traumatic brain injury. Comput Struct Biotechnol J. 2021;19:1002–13.
Article CAS PubMed PubMed Central Google Scholar
Ding Z, Wang Y, Zhong R, Feng Y, Xia T, Xie Y, et al. Systems pharmacology reveals the mechanism of activity of Physalis alkekengi L. var. franchetii against lipopolysaccharide-induced acute lung injury. J Cell Mol Med. 2020;24(9):5039–56.
Article PubMed PubMed Central Google Scholar
Zhang Z, Xie Z, Lv S, Shi Y, Zhai C, Li X, et al. Integrated metabolomics and network pharmacology study on the mechanism of Kangfuxiaoyan suppository for treating chronic pelvic inflammatory disease. Front Pharmacol. 2022;13:812587.
Article CAS PubMed PubMed Central Google Scholar
Fan X, Wu J, Yang H, Yan L, Wang S. Paeoniflorin blocks the proliferation of vascular smooth muscle cells induced by platelet-derived growth factor-BB through ROS mediated ERK1/2 and p38 signaling pathways. Mol Med Rep. 2018;17(1):1676–82.
Zhai XT, Zhang ZY, Jiang CH, Chen JQ, Ye JQ, Jia XB, et al. Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway. J Ethnopharmacol. 2016;183:159–65.
Das UN. Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: a review. J Adv Res. 2018;11:57–66.
Article CAS PubMed PubMed Central Google Scholar
Li C, Wang Z, Chen W, Cao B, Zhang M, Gu Q, et al. An integrative metabolomic and network pharmacology study revealing the regulating properties of xihuang pill that improves anlotinib effects in lung cancer. Front Oncol. 2021;11:697247.
Article PubMed PubMed Central Google Scholar
Ruan Y, Fan Y, Xie Y, Ma C, Mo B, Lai Y, et al. Modified Xiaoqinglong decoction alleviates lipopolysaccharide-induced acute lung injury in mice by regulating arachidonic acid metabolism and exerting anti-apoptotic and anti-inflammatory effects. Anat Rec (Hoboken). 2022;305(7):1672–81.
Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK. Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling. FASEB J. 2016;30(8):2792–801.
Article CAS PubMed PubMed Central Google Scholar
Norris PC, Arnardottir H, Sanger JM, Fichtner D, Keyes GS, Serhan CN. Resolvin D3 multi-level proresolving actions are host protective during infection. Prostaglandins Leukot Essent Fatty Acids. 2018;138:81–9.
留言 (0)