The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus

Formiga F, Camafort M, Carrasco Sánchez FJ. Heart failure and diabetes: The confrontation of two major epidemics of the 21st century. Rev Clin Esp. 2020 Mar;220(2):135–8.

Article  CAS  PubMed  Google Scholar 

Lindman BR, Dávila-Román VG, Mann DL, McNulty S, Semigran MJ, Lewis GD, et al. Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study. J Am Coll Cardiol. 2014;64(6):541–9.

Article  PubMed Central  PubMed  Google Scholar 

Shah AD, Langenberg C, Rapsomaniki E, Denaxas S, Pujades-Rodriguez M, Gale CP, et al. Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1?9 million people. Lancet. 2015;26(385 Suppl 1):86.

Article  Google Scholar 

Avogaro A, Azzolina D, Fadini GP, Baldi I. Incidence of heart failure in patients with type 1 diabetes: a systematic review of observational studies. J Endocrinol Invest. 2021;44(4):745–53.

Article  CAS  PubMed  Google Scholar 

Nichols GA, Hillier TA, Erbey JR, Brown JB. Congestive heart failure in type 2 diabetes: prevalence, incidence, and risk factors. Diabetes Care. 2001;24:1614–9.

Article  CAS  PubMed  Google Scholar 

From AM, Leibson CL, Bursi F, Redfield MM, Weston SA, Jacobsen SJ, et al. Diabetes in heart failure: prevalence and impact on outcome in the population. Am J Med. 2006;119:591–9.

Article  PubMed  Google Scholar 

McHugh K, DeVore AD, Wu J, Matsouaka RA, Fonarow GC, Heidenreich PA, et al. Heart failure with preserved ejection fraction and diabetes: JACC state-of-the-art review. J Am Coll Cardiol. 2019;73(5):602–11.

Article  PubMed  Google Scholar 

Fonarow GC, Stough WG, Abraham WT, Albert NM, Gheorghiade M, Greenberg BH, et al. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol. 2007;50(8):768–77.

Article  PubMed  Google Scholar 

Bugger H, Abel ED. Molecular mechanisms of diabetic cardiomyopathy. Diabetologia. 2014;57(4):660–71.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Rydén L, Grant PJ, Anker SD, Berne C, Cosentino F, Danchin N, et al. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD). Eur Heart J. 2013;34(39):3035–87.

Article  PubMed  Google Scholar 

Gøtzsche O, Darwish A, Gøtzsche L, Hansen LP, Sørensen KE. Incipient cardiomyopathy in young insulin-dependent diabetic patients: a seven-year prospective Doppler echocardiographic study. Diabet Med. 1996;13(9):834–40.

Article  PubMed  Google Scholar 

Rosengren A, Vestberg D, Svensson AM, Kosiborod M, Clements M, Rawshani A, et al. Long-term excess risk of heart failure in people with type 1 diabetes: a prospective case-control study. Lancet Diabetes Endocrinol. 2015;3(11):876–85.

Article  PubMed  Google Scholar 

Evangelista I, Nuti R, Picchioni T, Dotta F, PalazzuoliInt A. Molecular Dysfunction and Phenotypic Derangement in Diabetic Cardiomyopathy. J Mol Sci. 2019;20(13):3264.

Article  CAS  Google Scholar 

Borghetti G, von Lewinski D, Eaton DM, Sourij H, Houser SR, Wallner M. Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control. Front Physiol. 2018;9:1514.

Article  PubMed Central  PubMed  Google Scholar 

Tan Y, Zhang Z, Zheng C, Wintergerst KA, Keller BB, Cai L. Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence. Nat Rev Cardiol. 2020;17:585–607.

Article  PubMed Central  PubMed  Google Scholar 

Spillmann F, Linthout SV, Tschöpe C. Cardiac effects of HDL and its components on diabetic cardiomyopathy. Endocr Metab Immune Disord Drug Targets. 2012;12(2):132–47.

Article  CAS  PubMed  Google Scholar 

Xu X, Luo Z, He Y, Shan J, Guo J, Li J. Application of untargeted lipidomics based on UHPLC-high resolution tandem MS analysis to profile the lipid metabolic disturbances in the heart of diabetic cardiomyopathy mice. J Pharm Biomed Anal. 2020;190:113525.

Article  CAS  PubMed  Google Scholar 

Shirazi LF, Bissett J, Romeo F, Mehta JL. Role of inflammation in heart failure. Curr Atheroscler Rep. 2017;19(6):27.

Article  PubMed  Google Scholar 

Murphy SP, Kakkar R, McCarthy CP, Januzzi JL Jr. Inflammation in heart failure: JACC state-of-the-art review. J Am Coll Cardiol. 2020;75(11):1324–40.

Article  PubMed  Google Scholar 

Duprez DA, Otvos J, Sanchez OA, Mackey RH, Tracy R, Jacobs DR Jr. Comparison of the predictive value of GlycA and other biomarkers of inflammation for total death, incident cardiovascular events, noncardiovascular and noncancer inflammatory-related events, and total cancer events. Clin Chem. 2016;62(7):1020–31.

Article  CAS  PubMed  Google Scholar 

Akinkuolie AO, Buring JE, Ridker PM, Mora S. A novel protein glycan biomarker and future cardiovascular disease events. J Am Heart Assoc. 2014;3(5):e001221.

Article  PubMed Central  PubMed  Google Scholar 

Ritchie RH, Zerenturk EJ, Prakoso D, Calkin AC. Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy. J Mol Endocrinol. 2017;58(4):R225–40.

Article  CAS  PubMed  Google Scholar 

Herrero P, Peterson LR, McGill JB, Matthew S, Lesniak D, Dence C, et al. Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus. JACC. 2006;47(3):598–604.

Article  CAS  PubMed  Google Scholar 

Varbo A, Nordestgaard BG. Remnant cholesterol and ischemic heart disease. Curr Opin Lipidol. 2014;25(4):266–73.

Article  CAS  PubMed  Google Scholar 

Jensen MT, Sogaard P, Andersen HU, Bech J, Hansen TF, Galatius S, et al. Prevalence of systolic and diastolic dysfunction in patients with type 1 diabetes without known heart disease: the Thousand & 1 Study. Diabetologia. 2014;57(4):672–80.

Article  CAS  PubMed  Google Scholar 

Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18(12):1440–63.

Article  PubMed  Google Scholar 

Mallol R, Amigó N, Rodríguez MA, Heras M, Vinaixa M, Plana N, et al. Liposcale: a novel advanced lipoprotein test based on 2D diffusion-ordered 1H NMR spectroscopy. J Lipid Res. 2015;56(3):737–46.

Article  CAS  PubMed Central  PubMed  Google Scholar 

Fuertes-Martín R, Taverner D, Vallvé JC, Paredes S, Masana L, Correig X, et al. Characterization of 1H NMR Plasma Glycoproteins as a New Strategy To Identify Inflammatory Patterns in Rheumatoid Arthritis. J Proteome Res. 2018;17(11):3730–9.

Article  PubMed  Google Scholar 

Fuertes-Martín R, Moncayo S, Insenser M, Martínez-García MA, Luque-Ramírez M, Amigó Grau N, et al. Glycoprotein A and B Height-to-Width Ratios as Obesity-Independent Novel Biomarkers of Low-Grade Chronic Inflammation in Women with Polycystic Ovary Syndrome (PCOS). J Proteome Res. 2019;18(11):4038–4045.

Bro R, Smilde AK. Principal component analysis. Anal Methods. 2014;6:2812–31.

Article  CAS  Google Scholar 

Lee LC, Liong CY, Jemain AA. Partial least squares-discriminant analysis (PLS-DA) for classification of high-dimensional (HD) data: a review of contemporary practice strategies and knowledge gaps. Analyst. 2018;143(15):3526–39.

Article  CAS  PubMed  Google Scholar 

Riehle C, Bauersachs J. Of mice and men: models and mechanisms of diabetic cardiomyopathy. Basic Res Cardiol. 2018;114(1):2.

Article  PubMed Central  PubMed  Google Scholar 

Riehle C, Bauersachs J. Key inflammatory mechanisms underlying heart failure. Herz. 2019:96–106.

Otvos JD, Shalaurova I, Wolak-Dinsmore J, Connelly MA, Mackey RH, Stein JH, et al. GlycA: a composite nuclear magnetic resonance biomarker of systemic inflammation. Clin Chem. 2015;61(5):714–23.

Article  CAS  PubMed  Google Scholar 

Fuertes-Martín R, Correig X, Vallvé JC, Amigó N. Title: human serum/plasma glycoprotein analysis by 1H-NMR, an emerging method of inflammatory assessment. J Clin Med. 2020;9(2):354.

Article  PubMed Central  PubMed  Google Scholar 

Ballout RA, Remaley AT. GlycA: a new biomarker for systemic inflammation and cardiovascular disease (CVD) risk assessment. J Lab Precis Med. 2020;5:17.

Article  PubMed Central  PubMed  Google Scholar 

Rodríguez-Carrio J, Alperi-López M, López P, Pérez-Álvarez AI, Gil-Serret M, Amigó N, et al. GlycA levels during the earliest stages of rheumatoid arthritis: potential use as a biomarker of subclinical cardiovascular disease. J Clin Med. 2020;9(8):2472.

Article  PubMed Central  PubMed  Google Scholar 

Carmona-Maurici J, Amigó N, Cuello E, Bermúdez M, Baena-Fustegueras JA, Peinado-Onsurbe J. Bariatric surgery decreases oxidative stress and protein glycosylation in patients with morbid obesity. Eur J Clin Invest. 2020;50(11):e13320.

Article  CAS  PubMed  Google Scholar 

Mehta NN, Dey AK, Maddineni R, Kraus WE, Huffman KM. GlycA measured by NMR spectroscopy is associated with disease activity and cardiovascular disease risk in chronic inflammatory diseases. Am J Prev Cardiol. 2020;4:100120.

Article  PubMed Central  PubMed  Google Scholar 

Connelly MA, Otvos JD, Shalaurova I, Playford MP, Mehta NN. GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk. J Transl Med. 2017;15:219.

Article  PubMed Central  PubMed  Google Scholar 

Moncayo S, Insenser M, Martínez-García MA, Fuertes-Martín R, Amigó-Grau N, Álvarez-Blasco F, et al. Acute-phase glycoprotein profile responses to different oral macronutrient challenges: Influence of sex, functional hyperandrogenism and obesity. Clin Nutr. 2021;40(3):1241–6.

Article  CAS 

留言 (0)

沒有登入
gif