Cannon TD, Chung Y, He G, Sun D, Jacobson A, van Erp TGM, et al. Progressive reduction in cortical thickness as psychosis develops: a multisite longitudinal neuroimaging study of youth at elevated clinical risk. Biol Psychiatry. 2015;77:147–57.
Pantelis C, Velakoulis D, McGorry PD, Wood SJ, Suckling J, Phillips LJ, et al. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet. 2003;361:281–8.
Sun D, Phillips L, Velakoulis D, Yung A, McGorry PD, Wood SJ, et al. Progressive brain structural changes mapped as psychosis develops in ‘at risk’ individuals. Schizophrenia Res. 2009;108:85–92.
Ziermans TB, Schothorst PF, Schnack HG, Koolschijn PCMP, Kahn RS, van Engeland H, et al. Progressive structural brain changes during development of psychosis. Schizophrenia Bull. 2012;38:519–30.
Borgwardt SJ, McGuire PK, Aston J, Gschwandtner U, Pflüger MO, Stieglitz R-D, et al. Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophrenia Res. 2008;106:108–14.
Takahashi T, Wood SJ, Yung AR, Soulsby B, McGorry PD, Suzuki M, et al. Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis. Arch Gen Psychiatry. 2009;66:366–76.
Feinberg I. Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? J Psychiatr Res. 1982;17:319–34.
McGlashan TH, Hoffman RE. Schizophrenia as a disorder of developmentally reduced synaptic connectivity. Arch Gen Psychiatry. 2000;57:637–48.
Article CAS PubMed Google Scholar
Glausier JR, Lewis DA. Dendritic spine pathology in schizophrenia. Neuroscience 2013;251:90–107.
Article CAS PubMed Google Scholar
Stephan KE, Friston KJ, Frith CD. Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophrenia Bull. 2009;35:509–27.
Bentall RP, Morrison AP. More harm than good: the case against using antipsychotic drugs to prevent severe mental illness. J Ment Health. 2002;11:351–6.
Ruhrmann S, Schultze-Lutter F, Salokangas RKR, Heinimaa M, Linszen D, Dingemans P, et al. Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study. Arch Gen Psychiatry. 2010;67:241–51.
Cannon TD, Cadenhead K, Cornblatt B, Woods SW, Addington J, Walker E, et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry. 2008;65:28–37.
Article PubMed PubMed Central Google Scholar
Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton MJ, Valmaggia L, et al. Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk. Arch Gen Psychiatry. 2012;69:220–9.
Coyle JT, Tsai G, Goff D. Converging evidence of NMDA receptor hypofunction in the pathophysiology of schizophrenia. Ann NY Acad Sci. 2003;1003:318–27.
Article CAS PubMed Google Scholar
Keshavan MS, Anderson S, Pettergrew JW. Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited. J Psychiatr Res. 1994;28:239–65.
Article CAS PubMed Google Scholar
Stephan KE, Baldeweg T, Friston KJ. Synaptic plasticity and dysconnection in schizophrenia. Biol Psychiatry. 2006;59:929–39.
Article CAS PubMed Google Scholar
Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry. 2005;10:40–68.
Article CAS PubMed Google Scholar
Frick LR, Williams K, Pittenger C. Microglial dysregulation in psychiatric disease. Clin Dev Immunol. 2013;2013:608654.
Fillman SG, Cloonan N, Catts VS, Miller LC, Wong J, McCrossin T, et al. Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia. Mol Psychiatry. 2013;18:206–14.
Article CAS PubMed Google Scholar
Catts VS, Wong J, Fillman SG, Fung SJ, Shannon Weickert C. Increased expression of astrocyte markers in schizophrenia: association with neuroinflammation. Aust NZ J Psychiatry. 2014;48:722–34.
Schafer DP, Lehrman EK, Stevens B. The “quad‐partite” synapse: Microglia‐synapse interactions in the developing and mature CNS. Glia 2013;61:24–36.
Cannon TD. Brain biomarkers of vulnerability and progression to psychosis. Schizophrenia Bull. 2016;42:S127–32.
McGlashan T, Walsh B, Woods S. The psychosis-risk syndrome: handbook for diagnosis and follow-up. Oxford University Press; 2010.
Addington J, Liu L, Brummitt K, Bearden CE, Cadenhead KS, Cornblatt BA, et al. North American Prodrome Longitudinal Study (NAPLS 3): Methods and baseline description. Schizophrenia Res. 2022;243:262–7.
Desikan RS, Ségonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. NeuroImage. 2006;31:968–80.
Glasser MF, Sotiropoulos SN, Wilson JA, Coalson TS, Fischl B, Andersson JL, et al. The minimal preprocessing pipelines for the Human Connectome Project. Neuroimage. 2013;80:105–24.
Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. PNAS. 2000;97:11050–55.
Article CAS PubMed PubMed Central Google Scholar
Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron. 2002;33:341–55.
Article CAS PubMed Google Scholar
Reuter M, Schmansky NJ, Rosas HD, Fischl B. Within-subject template estimation for unbiased longitudinal image analysis. Neuroimage. 2012;61:1402–18.
Reuter M, Rosas HD, Fischl B. Highly accurate inverse consistent registration: a robust approach. Neuroimage. 2010;53:1181–96.
Triana AM, Glerean E, Saramäki J, Korhonen O. Effects of spatial smoothing on group-level differences in functional brain networks. Netw Neurosci. 2020;4:556–74.
Article PubMed PubMed Central Google Scholar
Zeighami Y, Evans AC. Association vs. prediction: the impact of cortical surface smoothing and parcellation on brain age. Front Big Data. 2021;4:15.
Bernal-Rusiel JL, Greve DN, Reuter M, Fischl B, Sabuncu MR, Initiative ADN. Statistical analysis of longitudinal neuroimage data with linear mixed effects models. Neuroimage. 2013;66:249–60.
Bernal-Rusiel JL, Reuter M, Greve DN, Fischl B, Sabuncu MR. Spatiotemporal linear mixed effects modeling for the mass-univariate analysis of longitudinal neuroimage data. NeuroImage. 2013;81:358–70.
Van Essen DC, Smith SM, Barch DM, Behrens TE, Yacoub E, Ugurbil K, et al. The WU-Minn human connectome project: an overview. Neuroimage. 2013;80:62–79.
Canty AJ. Resampling methods in R: the boot package. The Newsletter of the R Project Volume. 2002;2.
Brandt J. The Hopkins Verbal Learning Test: Development of a new memory test with six equivalent forms. Clin Neuropsychologist. 1991;5:125–42.
Keefe RS, Goldberg TE, Harvey PD, Gold JM, Poe MP, Coughenour L. The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery. Schizophrenia Res. 2004;68:283–97.
Borum R, Bartel P, Forth AE. SAVRY, Structured assessment of violence risk in youth: professional manual. Psychological Assessment Resources, Incorporated; 2006.
Leucht S, Samara M, Heres S, Patel MX, Woods SW, Davis JM. Dose equivalents for second-generation antipsychotics: the minimum effective dose method. Schizophrenia Bull. 2014;40:314–26.
Fornito A, Yung AR, Wood SJ, Phillips LJ, Nelson B, Cotton S, et al. Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individuals. Biol Psychiatry. 2008;64:758–65.
Jung WH, Kim JS, Jang JH, Choi J-S, Jung MH, Park J-Y, et al. Cortical thickness reduction in individuals at ultra-high-risk for psychosis. Schizophrenia Bull. 2011;37:839–49.
Rosen M, Betz LT, Schultze-Lutter F, Chisholm K, Haidl TK, Kambeitz-Ilankovic L, et al. Towards clinical application of prediction models for transition to psychosis: A systematic review and external validation study in the PRONIA sample. Neurosci Biobehav Rev. 2021;125:478–92.
Cannon TD, Yu C, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, et al. An individualized risk calculator for research in prodromal psychosis. AJP. 2016;173:980–88.
Carrión RE, Cornblatt BA, Burton CZ, Tso IF, Auther AM, Adelsheim S, et al. Personalized prediction of psychosis: external validation of the NAPLS-2 psychosis risk calculator with the EDIPPP project. AJP. 2016;173:989–96.
Koutsouleris N, Kambeitz-Ilankovic L, Ruhrmann S, Rosen M, Ruef A, Dwyer DB, et al. Prediction models of functional outcomes for individuals in the clinical high-risk state for psychosis or with recent-onset depression: a multimodal, multisite machine learning analysis. JAMA Psychiatry. 2018;75:1156–72.
留言 (0)