We thank Igor Roninson and Taras Nazarko (Georgia State University, Atlanta, GA) for critical reading of our manuscript; we thank B. Celia Cui and Alexandra Sikirzhytski for help with the preparation of publication-quality figures. We thank Microscopy and Flow cytometry core and core director Vitali Sikirzhytski, UofSC COBRE Center for Targeted Therapeutics for the help with image acquisition and analysis and flow cytometry analysis.