Post BNT162b2 mRNA COVID-19 vaccination Henoch-Schönlein Pupura

Introduction

Administration of BNT162b2 mRNA COVID-19 vaccine on a large scale was performed to combat the COVID-19 pandemic. Leading to the identification of various rare but significant vaccine-associated side effects one of which is myocarditis and pericarditis post vaccination.1 There have been reports of COVID-19 vaccine-associated vasculitis, both as a new onset IgA-positive leukocytoclastic vasculitis in an otherwise healthy adult man and also a leukocytoclastic vasculitis flare in an adult woman with autoimmune conditions.2 3

Case report

Our case is a 15-year-old Indian girl presenting with bilateral lower limb rash 2 hours after second dose of BNT162b2 mRNA COVID-19 vaccination, and 1 week after her first dose. The rash started at the right medial knee before spreading to bilateral lower limbs. The maculopapular rash was purpuric, palpable and non-blanching. She also had a fever and a tender right ankle swelling (figure 1). No angioedema, no wheeze or dyspnoea was noted. The patient has a history of atopy …

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