Interdisciplinary care of children with diffuse midline glioma

ElsevierVolume 35, January 2023, 100851NeoplasiaAuthor links open overlay panelHighlights•

Diffuse midline glioma is a terminal disease that requires interdisciplinary care.

Biopsy should be offered to patients with diffuse midline glioma.

Clinical trial enrollment remains the cornerstone of DMG therapy.

Abstract

Diffuse Midline Glioma (DMG) which includes Diffuse Intrinsic Pontine Glioma (DIPG) is an infiltrative tumor of the midline structures of the central nervous system that demonstrates an aggressive pattern of growth and has no known curative treatment. As these tumors progress, children experience ongoing neurological decline including inability to ambulate, swallow and communicate effectively. We propose that optimal care for patients with DMG should involve a specialized team experienced in caring for the multifaceted needs of these patients and their families. Herein we review the roles and evidence to support early involvement of a specialized interdisciplinary team and outline our views on best practices for these challenging tumors.

Keywords

Diffuse Midline glioma

DIPG

Interdisciplinary care

Best practices

© 2022 The Authors. Published by Elsevier Inc.

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