Glued to the nerves

Peripheral nerve injuries affect communication between the brain and the rest of the body. Common nerve repair strategies use sutures, which can cause inflammation and scarring. Biological glues based on fibrin have been used to mitigate these adverse effects, but they typically have poor nerve adhesion. Bin Duan and colleagues devised a hydrogel adhesive to successfully heal transected nerves. The adhesive was made from two different polymer networks, providing good adhesion strength while supplying bioactive compounds that promote nerve regeneration. Because of the adhesive’s healing properties, its application to rats with transected sciatic nerves improved muscle function, and inflammation and scarring were alleviated.

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