Abais J, Zhang C, Xia M, Liu Q, Gehr T, Boini K, Li P. NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal. 2013;18:1537–48.

Article  CAS  PubMed  PubMed Central  Google Scholar 

An X, Zhang Y, Cao Y, Chen J, Qin H, Yang L. Punicalagin protects diabetic nephropathy by inhibiting pyroptosis based on TXNIP/NLRP3 pathway. Nutrients. 2020;12:1516.

Article  CAS  PubMed Central  Google Scholar 

Burdette B, Esparza A, Zhu H, Wang S. Gasdermin D in pyroptosis. Acta Pharm Sinica B. 2021;11:2768–82.

Article  CAS  Google Scholar 

Chen Z, Zhang C, Gao F, Fu Q, Fu C, He Y, Zhang J. A systematic review on the rhizome of Ligusticum chuanxiong Hort. (Chuanxiong). Food Chem Toxicol. 2018;119:309–25.

Article  CAS  Google Scholar 

Dai H, Hu W, Lin L, Wang L, Chen J, He Y. Tubular decoy receptor 2 as a predictor of prognosis in patients with immunoglobulin A nephropathy. Clin kidney J. 2021a;14:1458–68.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dai X, Liao R, Liu C, Liu S, Huang H, Liu J, Jin T, Guo H, Zheng Z, Xia M, Ling W, Xiao Y. Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy. Redox Biol. 2021b;45:102033.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han J, Zuo Z, Shi X, Zhang Y, Peng Z, Xing Y, Pang X. Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis. Cell Biol Toxicol. 2021. https://doi.org/10.1007/s10565-021-09622-z.

Article  PubMed  Google Scholar 

Hong J, Bhat O, Li G, Dempsey S, Zhang Q, Ritter J, Li W, Li P. Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes. Biochimica et biophysica acta. Mol cell Res. 2019;1866:849–60.

CAS  Google Scholar 

Li F, Chen Y, Li Y, Huang M, Zhao W. Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway. Eur J Pharmacol. 2020a;886:173449.

Article  CAS  PubMed  Google Scholar 

Li M, Guo Q, Cai H, Wang H, Ma Z, Zhang X. miR-218 regulates diabetic nephropathy via targeting IKK-β and modulating NK-κB-mediated inflammation. J Cell Physiol. 2020b;235:3362–71.

Article  CAS  PubMed  Google Scholar 

Lin J, Cheng A, Cheng K, Deng Q, Zhang S, Lan Z, Wang W, Chen J. New insights into the mechanisms of pyroptosis and implications for diabetic kidney disease. Int J Mol Sci. 2020;21:7057.

Article  CAS  PubMed Central  Google Scholar 

Lin J, Wang Q, Zhou S, Xu S, Yao K. Tetramethylpyrazine: a review on its mechanisms and functions. Biomed Pharmacother. 2022;150:113005.

Article  CAS  PubMed  Google Scholar 

Liu B, Lu R, Li H, Zhou Y, Zhang P, Bai L, Chen D, Chen J, Li J, Yu P, Wu J, Liang C, Song J, Liu X, Zhou J. Zhen-wu-tang ameliorates membranous nephropathy rats through inhibiting NF-κB pathway and NLRP3 inflammasome. Phytomedicine. 2019;59:152913.

Article  CAS  PubMed  Google Scholar 

Liu P, Zhang Z, Li Y. Relevance of the pyroptosis-related inflammasome pathway in the pathogenesis of diabetic kidney disease. Front Immunol. 2021;12:603416.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Xu Z, Ma F, Jia Y, Wang G. Knockdown of TLR4 attenuates high glucose-induced podocyte injury via the NALP3/ASC/Caspase-1 signaling pathway. Biomed Pharmacother. 2018;107:1393–401.

Article  CAS  PubMed  Google Scholar 

Rai U, Kosuru R, Prakash S, Tiwari V, Singh S. Tetramethylpyrazine alleviates diabetic nephropathy through the activation of Akt signalling pathway in rats. Eur J Pharmacol. 2019;865:172763.

Article  CAS  PubMed  Google Scholar 

Rühl S, Shkarina K, Demarco B, Heilig R, Santos J, Broz P. ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation. 362. New York: Science; 2018. pp. 956–60.

Google Scholar 

Shahzad K, Bock F, Dong W, Wang H, Kopf S, Kohli S, Al-Dabet M, Ranjan S, Wolter J, Wacker C, Biemann R, Stoyanov S, Reymann K, Söderkvist P, Groß O, Schwenger V, Pahernik S, Nawroth P, Gröne H, Madhusudhan T, Isermann B. Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy. Kidney Int. 2015;87:74–84.

Article  CAS  PubMed  Google Scholar 

Song S, Qiu D, Shi Y, Wang S, Zhou X, Chen N, Wei J, Wu M, Wu H, Duan H. Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy. J Cell Physiol. 2019. https://doi.org/10.1002/jcp.28317.

Article  PubMed  PubMed Central  Google Scholar 

Tan H, Zhao Q, Chen L. Penehyclidine hydrochloride suppresses inflammation response and reduces podocyte injury in diabetic nephropathy by targeting fibrinogen-like protein 2. Int Immunopharmacol. 2022;107:108680.

Article  CAS  PubMed  Google Scholar 

Tang S, Yiu W. Innate immunity in diabetic kidney disease. Nat Rev Nephrol. 2020;16:206–22.

Article  CAS  PubMed  Google Scholar 

Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, Cui J, Bai L, Wang J, Jiang W, Zhou R. CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation. Nat Commun. 2017;8:202.

Article  PubMed  PubMed Central  Google Scholar 

Tricò D, McCollum S, Samuels S, Santoro N, Galderisi A, Groop L, Caprio S, Shabanova V. Mechanistic insights into the heterogeneity of glucose response classes in youths with obesity. A latent class trajectory approach. Diabetes care. 2022;45(8):1841–51.

Article  PubMed  PubMed Central  Google Scholar 

Vo T, Lee C, Chiang Y, Chen Y, Yu Y, Tuan V, Wu C, Lee I. Protective mechanisms of Taiwanese green propolis toward high glucose-induced inflammation via NLRP3 inflammasome signaling pathway in human gingival fibroblasts. J Periodontal Res. 2021;56:804–18.

Article  CAS  PubMed  Google Scholar 

Wang A, Gong Y, Pei Z, Jiang L, Xia L, Wu Y. Paeoniflorin ameliorates diabetic liver injury by targeting the TXNIP-mediated NLRP3 inflammasome in db/db mice. Int Immunopharmacol. 2022a;109:108792.

Article  CAS  PubMed  Google Scholar 

Wang A, Zhang D, Liu J, Yan H, Zhang P, Yuan H, Ma X. Guanxinning injection combined with ischemic postconditioning attenuate myocardial ischemic reperfusion injury in chronic renal failure rats by modulating mitochondrial dynamics. Front Cardiovasc Med. 2022;9:905254.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Wang L, Zhou H, Liang X, Zhang M, Tang Y, Wang J, Mao J. The isolation, structural features and biological activities of polysaccharide from Ligusticum chuanxiong: a review. Carbohydr Polym. 2022c;285:118971.

Article  CAS  PubMed  Google Scholar 

Wang J, Zhao S. LncRNA-antisense non-coding RNA in the INK4 locus promotes pyroptosis via miR-497/thioredoxin-interacting protein axis in diabetic nephropathy. Life Sci. 2021;264:118728.

Article  CAS  PubMed  Google Scholar 

Wang R, Wu Y, An D, Ma P, Guo Y, Tang L. Case report: glucocorticoids combined with immunosuppressant in the treatment of acromegaly complicated with focal segmental glomerulosclerosis. Front Med. 2020;7:563020.

Article  Google Scholar 

Wang Y, Huang J, Chen W, Wang R, Kao M, Pan Y, Chan S, Tsai K, Kung H, Lin K, Wang L. Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis. EMBO Rep. 2019;20:e45986.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wonnacott A, Denby L, Coward R, Fraser D, Bowen TJA. MicroRNAs and their delivery in diabetic fibrosis. Adv Drug Deliv Rev. 2022;182:114045.

Article  CAS  PubMed  Google Scholar 

Wu C, Liu J, Li Y, Wang N, Yan Q, Jiang Z. Manno-oligosaccharides from cassia seed gum ameliorate inflammation and improve glucose metabolism in diabetic rats. Food Funct. 2022;13:6674–87.

Article  CAS  PubMed  Google Scholar 

Wu K, Long K, Lin H, Siu P, Hoo R, Ye D, Xu A, Cheng K. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages. Nat Commun. 2021;12:6637.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xu X, Huang X, Zhang L, Huang X, Qin Z, Hua F. Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway. BMC Nephrol. 2021;22:218.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xue L, Lu B, Gao B, Shi Y, Xu J, Yang R, Xu B, Ding P. NLRP3 promotes glioma cell proliferation and invasion via the interleukin-1β/NF-κB p65 signals. Oncol Res. 2019;27:557–64.

Article  PubMed  PubMed Central  Google Scholar 

Yang J, Yu X, Hu N, Su T. Clinical and pathological features of renal presentations in polycythemia vera. Am J Med Sci. 2022;363:33–41.

Article  PubMed