Orthobiologic Interventions for Muscle Injuries

Fernandez W.G. Yard E.E. Comstock R.D.

Epidemiology of lower extremity injuries among US high school athletes.

Acad Emerg Med. 14: 641-645Ekstrand J. Hägglund M. Waldén M.

Epidemiology of muscle injuries in professional football (soccer).

Am J Sports Med. 39: 1226-1232Chan O. Del Buono A. Best T.M. et al.

Acute muscle strain injuries: a proposed new classification system.

Knee Surg Sports Traumatol Arthrosc. 20: 2356-2362Järvinen M.J. Lehto M.U.

The effects of early mobilisation and immobilisation on the healing process following muscle injuries.

Sports Med. 15: 78-89Järvinen T.A. Järvinen M. Kalimo H.

Regeneration of injured skeletal muscle after the injury.

Muscles Ligaments Tendons J. 3: 337-345Kalimo H. Rantanen J. Järvinen M.

Muscle injuries in sports.

Bailliere's Clin Orthopaedics. 2: 1-24Kujala U.M. Orava S. Järvinen M.

Hamstring injuries.

Sports Med. 23: 397-404

Keeping your top players on the pitch: the key to football medicine at a professional level.

Br J Sports Med. 47: 723-724

Skeletal muscle: functional anatomy and pathophysiology.

Semin Musculoskelet Radiol. 14: 97-105

Skeletal muscle: a brief review of structure and function.

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The neuromuscular junction.

Sports Med. 17: 358-372Mueller-Wohlfahrt H.-W. Haensel L. Mithoefer K. et al.

Terminology and classification of muscle injuries in sport: the Munich consensus statement.

Br J Sports Med. 47: 342-350Pollock N. James S.L. Lee J.C. et al.

British athletics muscle injury classification: a new grading system.

Br J Sports Med. 48: 1347-1351Camp C.L. Dines J.S. van der List J.P. et al.

Summative report on time out of play for major and minor league baseball: an analysis of 49,955 injuries from 2011 through 2016.

Am J Sports Med. 46: 1727-1732Rodas G. Bove T. Caparrós T. et al.

Ankle sprain versus muscle strain injury in professional men’s basketball: a 9-year prospective follow-up study.

Orthop J Sports Med. 7 ()

The frequency of occurrence, impact, cost of selected musculoskeletal conditions in the United States.

Am Acad Orthop Surgeon. 1: 73-75Anderson G.R. Melugin H.P. Stuart M.J.

Epidemiology of injuries in ice hockey.

Sports Health. 11: 514-519Gentile N.E. Stearns K.M. Brown E.H. et al.

Targeted rehabilitation after extracellular matrix scaffold transplantation for the treatment of volumetric muscle loss.

Am J Phys Med Rehabil. 93: S79-S87

Regenerative rehabilitation: applied biophysics meets stem cell therapeutics.

Cell Stem Cell. 22: 306-309

Introduction. Treatment of injuries to athletes. 1962.

Clin Orthop Relat Res. : 3-8Patel A. Chakraverty J. Pollock N. et al.

British athletics muscle injury classification: a reliability study for a new grading system.

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Intra-and interrater reliability of three different MRI grading and classification systems after acute hamstring injuries.

Eur J Radiol. 89: 182-190Sassoli C. Vallone L. Tani A. et al.

Combined use of bone marrow-derived mesenchymal stromal cells (BM-MSCs) and platelet rich plasma (PRP) stimulates proliferation and differentiation of myoblasts in vitro: new therapeutic perspectives for skeletal muscle repair/regeneration.

Cell Tissue Res. 372: 549-570Järvinen T.A. Järvinen T.L. Kääriäinen M. et al.

Muscle injuries: biology and treatment.

Am J Sports Med. 33: 745-764

Hypermobile joint: a preliminary report.

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An in situ study of a Sclerosing solution in rabbit medial collateral ligaments and its junction strength.

Connect Tissue Res. 11: 95-102

Comparison of tetradecyl sulfate versus polidocanol injections for stabilisation of joints that regularly dislocate in an Ehlers-Danlos population.

BMJ Open Sport Exerc Med. 5: e000481Tsai S.-W. Hsu Y.-J. Lee M.-C. et al.

Effects of dextrose prolotherapy on contusion-induced muscle injuries in mice.

Int J Med Sci. 15: 1251Dunn A. Talovic M. Patel K. et al.

Biomaterial and stem cell-based strategies for skeletal muscle regeneration.

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Intra-arterial MSC transplantation restores functional capacity after skeletal muscle trauma.

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Application of bone marrow-derived mesenchymal stem cells for muscle healing after contusion injury in mice.

Am J Sports Med. 48: 1226-1235Everts P. Onishi K. Jayaram P. et al.

Platelet-rich plasma: new performance understandings and therapeutic considerations in 2020.

Int J Mol Sci. : 21

Current insights into the potential misuse of platelet-based applications for doping in sports.

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Bone marrow mesenchymal cells improve muscle function in a skeletal muscle re-injury model.

PLoS One. 10: e0127561Tsuji W. Rubin J.P. Marra K.G.

Adipose-derived stem cells: implications in tissue regeneration.

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Myogenic differentiation by human processed lipoaspirate cells.

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Myogenic differentiation of stem cells for skeletal muscle regeneration.

Stem Cells Int. 2021: 8884283Pinheiro C.H. de Queiroz J.C. Guimarães-Ferreira L. et al.

Local injections of adipose-derived mesenchymal stem cells modulate inflammation and increase angiogenesis ameliorating the dystrophic phenotype in dystrophin-deficient skeletal muscle.

Stem Cell Rev Rep. 8: 363-374Lee E.M. Kim A.Y. Lee E.J. et al.

Therapeutic effects of mouse adipose-derived stem cells and losartan in the skeletal muscle of injured mdx mice.

Cell Transplant. 24: 939-953Wexler S.A. Donaldson C. Denning-Kendall P. et al.

Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not.

Br J Haematol. 121: 368-374Amati E. Sella S. Perbellini O. et al.

Generation of mesenchymal stromal cells from cord blood: evaluation of in vitro quality parameters prior to clinical use.

Stem Cell Res Ther. 8: 14Mishra S. Sevak J.K. Das A. et al.

Umbilical cord tissue is a robust source for mesenchymal stem cells with enhanced myogenic differentiation potential compared to cord blood.

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Wharton’s Jelly stem cells: future clinical applications.

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CD105(+) cells from Wharton's jelly show in vitro and in vivo myogenic differentiative potential.

Int J Mol Med. 18: 1089-1096Su W.-H. Wang C.-J. Fu H.-C. et al.

Human umbilical cord mesenchymal stem cells extricate bupivacaine-impaired skeletal muscle function via mitigating neutrophil-mediated acute inflammation and protecting against fibrosis.

Int J Mol Sci. 20: 4312Barlow S. Brooke G. Chatterjee K. et al.

Comparison of human placenta- and bone marrow-derived multipotent mesenchymal stem cells.

Stem Cells Dev. 17: 1095-1107Magatti M. Vertua E. Cargnoni A. et al.

The immunomodulatory properties of amniotic cells: the two sides of the coin.

Cell Transpl. 27: 31-44Winkler T. Perka C. von Roth P. et al.

Immunomodulatory placental-expanded, mesenchymal stromal cells improve muscle function following hip arthroplasty.

J Cachexia Sarcopenia Muscle. 9: 880-897Cruciani M. Franchini M. Mengoli C. et al.

Platelet-rich plasma for sports-related muscle, tendon and ligament injuries: an umbrella review.

Blood Transfus. 17: 465-478Mautner K. Malanga G.A. Smith J. et al.

A call for a standard classification system for future biologic research: the rationale for new PRP nomenclature.

PM&R. 7: S53-S59Miroshnychenko O. Chang W-t Dragoo J.L.

The use of platelet-rich and platelet-poor plasma to enhance differentiation of skeletal myoblasts: implications for the use of autologous blood products for muscle regeneration.

Am J Sports Med. 45: 945-953Chahla J. Cinque M.E. Piuzzi N.S. et al.

A call for standardization in platelet-rich plasma preparation protocols and composition reporting: a systematic review of the clinical orthopaedic literature.

J Bone Joint Surg Am. 99: 1769-1779Le A.D. Enweze L. DeBaun M.R. et al.

Platelet-rich plasma.

Clin Sports Med. 38: 17-44Rossi L. Murray I. Chu C. et al.

Classification systems for platelet-rich plasma.

Bone Joint J. 101: 891-896Denapoli P.M.A. Stilhano R.S. Ingham S.J.M. et al.

Platelet-rich plasma in a murine model: leukocytes, growth factors, Flt-1, and muscle healing.

Am J Sports Med. 44: 1962-1971Martins R.P. Hartmann D.D. de Moraes J.P. et al.

Platelet-rich plasma reduces the oxidative damage determined by a skeletal muscle contusion in rats.

Platelets. 27: 784-790Terada S. Ota S. Kobayashi M. et al.

Use of an antifibrotic agent improves the effect of platelet-rich plasma on muscle healing after injury.

J Bone Joint Surg Am. 95: 980-988Bubnov R. Yevseenko V. Semeniv I.

Ultrasound guided injections of platelets rich plasma for muscle injury in professional athletes. Comparative study.

Med Ultrason. 15: 101-105Hamilton B. Tol J.L. Almusa E. et al.

Platelet-rich plasma does not enhance return to play in hamstring injuries: a randomised controlled trial.

Br J Sports Med. 49: 943-950Martinez-Zapata M.J. Orozco L. Balius R. et al.

Efficacy of autologous platelet-rich plasma for the treatment of muscle rupture with haematoma: a multicentre, randomised, double-blind, placebo-controlled clinical trial.

Blood Transfus. 14: 245-254Hamid M.S.A. Mohamed Ali M.R. Yusof A. et al.

Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial.

Am J Sports Med. 42: 2410-2418Reurink G. Goudswaard G.J. Moen M.H. et al.

Rationale, secondary outcome scores and 1-year follow-up of a randomised trial of platelet-rich plasma injections in acute hamstring muscle injury: the Dutch Hamstring Injection Therapy study.

Br J Sports Med. 49: 1206-1212Reurink G. Goudswaard G.J. Moen M.H. et al.

Myotoxicity of injections for acute muscle injuries: a systematic review.

Sports Med. 44: 943-956Bezuglov E. Maffulli N. Tokareva A. et al.

Platelet-rich plasma in hamstring muscle injuries in professional soccer players: a pilot study.

Muscles Ligaments Tendons J. 9: 112-118Guillodo Y. Madouas G. Simon T. et al.

Platelet-rich plasma (PRP) treatment of sports-related severe acute hamstring injuries.

Muscles Ligaments Tendons J. 5: 284-288Rettig A.C. Meyer S. Bhadra A.K.

Platelet-rich plasma in addition to rehabilitation for acute hamstring injuries in NFL players: clinical effects and time to return to play.

Orthop J Sports Med. 1 ()Zanon G. Combi F. Combi A. et al.

Platelet-rich plasma in the treatment of acute hamstring injuries in professional football players.

Joints. 4: 17-23Güleçyüz M.F. Macha K. Pietschmann M.F. et al.

Allogenic myocytes and mesenchymal stem cells partially improve fatty rotator cuff degeneration in a rat model.

Stem Cell Rev Rep. 14: 847-859Takase F. Inui A. Mifune Y. et al.

Effect of platelet-rich plasma on degeneration change of rotator cuff muscles: in vitro and in vivo evaluations.

J Orthop Res. 35: 1806-1815Hotfiel T. Seil R. Bily W. et al.

Nonoperative treatment of muscle injuries-recommendations from the GOTS expert meeting.

J Exp Orthop. 5: 1-11Sciorati C. Rigamonti E. Manfredi A.A. et al.

Cell death, clearance and immunity in the skeletal muscle.

Cell Death Differ. 23: 927-937

Ultrasound of muscles.

Eur Radiol. 12: 35-43Trunz L.M. Landy J.E. Dodson C.C. et al.

Effectiveness of hematoma aspiration and platelet-rich plasma muscle injections for the treatment of hamstring strains in athletes.

Med Sci Sports Exerc. 54: 12-17Ling X. Ma X. Kuang X. et al.

Lidocaine inhibits myoblast cell migration and myogenic differentiation through activation of the notch pathway.

Drug Des Devel Ther. 15: 927-936Bedi A. Trinh T.Q. Olszewski A.M. et al.

Nonbiologic injections in sports medicine.

JBJS Rev. 8: e0052Ljungqvist A. Schwellnus M.P. Bachl N. et al.

International Olympic Committee consensus statement: molecular basis of connective tissue and muscle injuries in sport.

Clin Sports Med. 27 (): 231-239Engebretsen L. Steffen K. Alsousou J. et al.

IOC consensus paper on the use of platelet-rich plasma in sports medicine.

Br J Sports Med. 44: 1072-1081Cole B.J. Gilat R. DiFiori J. et al.

The 2020 NBA orthobiologics consensus statement.

Orthop J Sports Med. 9 ()Finnoff J.T. Awan T.M. Borg-Stein J. et al.

American Medical Society for sports medicine position statement: principles for the responsible use of regenerative medicine in sports medicine.

Clin J Sport Med. 31: 530-541

2019-2020 NFL and NFL physician society orthobiologics consensus statement.

Sports Health. 12: 58-60

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