Elevated platelet–leukocyte complexes are associated with, but dispensable for myocardial ischemia–reperfusion injury

Andrassy M, Volz HC, Maack B, Schuessler A, Gitsioudis G, Hofmann N, Laohachewin D, Wienbrandt AR, Kaya Z, Bierhaus A, Giannitsis E, Katus HA, Korosoglou G (2012) HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease. PLoS One 7(12):e52081. https://doi.org/10.1371/journal.pone.0052081

Article  CAS  PubMed  PubMed Central  Google Scholar 

Andrews RK, Berndt MC (2004) Platelet physiology and thrombosis. Thromb Res 114(5–6):447–453. https://doi.org/10.1016/j.thromres.2004.07.020

Article  CAS  PubMed  Google Scholar 

Aparicio-Vergara M, Shiri-Sverdlov R, de Haan G, Hofker MH (2010) Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases. Atherosclerosis 213(2):335–344. https://doi.org/10.1016/j.atherosclerosis.2010.05.030

Article  CAS  PubMed  Google Scholar 

Aurigemma C, Scalone G, Tomai F, Altamura L, de Persio G, Stazi A, Lanza GA, Crea F (2014) Persistent enhanced platelet activation in patients with acute myocardial infarction and coronary microvascular obstruction: clinical implications. Thromb Haemost 111(1):122–130. https://doi.org/10.1160/TH13-02-0166

Article  CAS  PubMed  Google Scholar 

Barrabés JA, Garcia-Dorado D, Mirabet M, Inserte J, Agulló L, Soriano B, Massaguer A, Padilla F, Lidón R-M, Soler-Soler J (2005) Antagonism of selectin function attenuates microvascular platelet deposition and platelet-mediated myocardial injury after transient ischemia. J Am Coll Cardiol 45(2):293–299. https://doi.org/10.1016/j.jacc.2004.09.068

Article  CAS  PubMed  Google Scholar 

Blair P, Flaumenhaft R (2009) Platelet alpha-granules: basic biology and clinical correlates. Blood Rev 23(4):177–189. https://doi.org/10.1016/j.blre.2009.04.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blann AD, Nadar SK, Lip GYH (2003) The adhesion molecule P-selectin and cardiovascular disease. Eur Heart J 24(24):2166–2179. https://doi.org/10.1016/j.ehj.2003.08.021

Article  CAS  PubMed  Google Scholar 

Burger PC, Wagner DD (2003) Platelet P-selectin facilitates atherosclerotic lesion development. Blood 101(7):2661–2666. https://doi.org/10.1182/blood-2002-07-2209

Article  CAS  PubMed  Google Scholar 

D’Ascenzo F, Moretti C, Omedè P, Cerrato E, Cavallero E, Er F, Presutti DG, Colombo F, Crimi G, Conrotto F, Dinicolantonio JJ, Chen S, Prasad A, Biondi Zoccai G, Gaita F (2014) Cardiac remote ischaemic preconditioning reduces periprocedural myocardial infarction for patients undergoing percutaneous coronary interventions: a meta-analysis of randomised clinical trials. EuroIntervention 9(12):1463–1471. https://doi.org/10.4244/EIJV9I12A244

Article  PubMed  Google Scholar 

Deppermann C, Kubes P (2018) Start a fire, kill the bug: the role of platelets in inflammation and infection. Innate Immun 24(6):335–348. https://doi.org/10.1177/1753425918789255

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dib PRB, Quirino-Teixeira AC, Merij LB, Pinheiro MBM, Rozini SV, Andrade FB, Hottz ED (2020) Innate immune receptors in platelets and platelet–leukocyte interactions. J Leukoc Biol 108(4):1157–1182. https://doi.org/10.1002/JLB.4MR0620-701R

Article  CAS  PubMed  Google Scholar 

Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD (2013) Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice. Blood 121(6):1008–1015. https://doi.org/10.1182/blood-2012-06-437392

Article  CAS  PubMed  PubMed Central  Google Scholar 

Estevez B, Du X (2017) New concepts and mechanisms of platelet activation signaling. Physiology (Bethesda) 32(2):162–177. https://doi.org/10.1152/physiol.00020.2016

Article  CAS  Google Scholar 

Finsterbusch M, Schrottmaier WC, Kral-Pointner JB, Salzmann M, Assinger A (2018) Measuring and interpreting platelet–leukocyte aggregates. Platelets 29(7):677–685. https://doi.org/10.1080/09537104.2018.1430358

Article  CAS  PubMed  PubMed Central  Google Scholar 

Frangogiannis N (2002) The inflammatory response in myocardial infarction. Cardiovasc Res 53(1):31–47. https://doi.org/10.1016/S0008-6363(01)00434-5

Article  CAS  PubMed  Google Scholar 

Frenette PS, Johnson RC, Hynes RO, Wagner DD (1995) Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci USA 92(16):7450–7454. https://doi.org/10.1073/pnas.92.16.7450

Article  CAS  PubMed  PubMed Central  Google Scholar 

Furie B, Furie BC (2005) Thrombus formation in vivo. J Clin Invest 115(12):3355–3362. https://doi.org/10.1172/JCI26987

Article  CAS  PubMed  PubMed Central  Google Scholar 

Furman MI, Barnard MR, Krueger LA, Fox ML, Shilale EA, Lessard DM, Marchese P, Frelinger AL, Goldberg RJ, Michelson AD (2001) Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction. J Am Coll Cardiol 38(4):1002–1006. https://doi.org/10.1016/s0735-1097(01)01485-1

Article  CAS  PubMed  Google Scholar 

Gleissner CA, von Hundelshausen P, Ley K (2008) Platelet chemokines in vascular disease. Arterioscler Thromb Vasc Biol 28(11):1920–1927. https://doi.org/10.1161/ATVBAHA.108.169417

Article  CAS  PubMed  PubMed Central  Google Scholar 

Götz AK, Zahler S, Stumpf P, Welsch U, Becker BF (2005) Intracoronary formation and retention of micro aggregates of leukocytes and platelets contribute to postischemic myocardial dysfunction. Basic Res Cardiol 100(5):413–421. https://doi.org/10.1007/s00395-005-0540-9

Article  PubMed  Google Scholar 

Habazettl H, Hanusch P, Kupatt C (2000) Effects of endothelium/leukocytes/platelet interaction on myocardial ischemia–reperfusion injury. Z Kardiol 89(Suppl 9):IX92–IX95. https://doi.org/10.1007/s003920070038

Article  Google Scholar 

Heusch G (2019) Coronary microvascular obstruction: the new frontier in cardioprotection. Basic Res Cardiol 114(6):45. https://doi.org/10.1007/s00395-019-0756-8

Article  CAS  PubMed  Google Scholar 

Hidari KI, Weyrich AS, Zimmerman GA, McEver RP (1997) Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils. J Biol Chem 272(45):28750–28756. https://doi.org/10.1074/jbc.272.45.28750

Article  CAS  PubMed  Google Scholar 

Kleinbongard P, Heusch G (2022) A fresh look at coronary microembolization. Nat Rev Cardiol 19(4):265–280. https://doi.org/10.1038/s41569-021-00632-2

Article  PubMed  Google Scholar 

Köhler D, Straub A, Weissmüller T, Faigle M, Bender S, Lehmann R, Wendel H-P, Kurz J, Walter U, Zacharowski K, Rosenberger P (2011) Phosphorylation of vasodilator-stimulated phosphoprotein prevents platelet–neutrophil complex formation and dampens myocardial ischemia-reperfusion injury. Circulation 123(22):2579–2590. https://doi.org/10.1161/CIRCULATIONAHA.110.014555

Article  CAS  PubMed  Google Scholar 

Kroll MH, Hellums JD, McIntire LV, Schafer AI, Moake JL (1996) Platelets and shear stress. Blood 88(5):1525–1541

Article  CAS  PubMed  Google Scholar 

Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B (1989) PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 59(2):305–312. https://doi.org/10.1016/0092-8674(89)90292-4

Article  CAS  PubMed  Google Scholar 

Leebeek FWG, Eikenboom JCJ (2016) Von Willebrand’s disease. N Engl J Med 375(21):2067–2080. https://doi.org/10.1056/NEJMra1601561

Article  CAS  PubMed  Google Scholar 

Lefer AM, Campbell B, Scalia R, Lefer DJ (1998) Synergism between platelets and neutrophils in provoking cardiac dysfunction after ischemia and reperfusion: role of selectins. Circulation 98(13):1322–1328. https://doi.org/10.1161/01.CIR.98.13.1322

Article  CAS  PubMed  Google Scholar 

Lefer DJ, Flynn DM, Buda AJ (1996) Effects of a monoclonal antibody directed against P-selectin after myocardial ischemia and reperfusion. Am J Physiol 270(1 Pt 2):H88–H98. https://doi.org/10.1152/ajpheart.1996.270.1.H88

Article  CAS  PubMed  Google Scholar 

Li JL, Zarbock A, Hidalgo A (2017) Platelets as autonomous drones for hemostatic and immune surveillance. J Exp Med 214(8):2193–2204. https://doi.org/10.1084/jem.20170879

Article  CAS  PubMed  PubMed Central  Google Scholar 

Linden MD, Jackson DE (2010) Platelets: pleiotropic roles in atherogenesis and atherothrombosis. Int J Biochem Cell Biol 42(11):1762–1766. https://doi.org/10.1016/j.biocel.2010.07.012

Article  CAS  PubMed  Google Scholar 

Manka D, Forlow SB, Sanders JM, Hurwitz D, Bennett DK, Green SA, Ley K, Sarembock IJ (2004) Critical role of platelet P-selectin in the response to arterial injury in apolipoprotein-E-deficient mice. Arterioscler Thromb Vasc Biol 24(6):1124–1129. https://doi.org/10.1161/01.ATV.0000127619.04687.f4

Article  CAS  PubMed  Google Scholar 

Massberg S, Enders G, Leiderer R, Eisenmenger S, Vestweber D, Krombach F, Messmer K (1998) Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectin. Blood 92(2):507–515

留言 (0)

沒有登入
gif