Introduction: It is common knowledge that any activity that results in caloric expenditure has the potential to prevent cardiovascular diseases, nonetheless, most people are physically inactive, especially office workers. This study sort to evaluate at baseline, the extent of physical inactivity and its determinants among staff of selected banks in Accra, Ghana. Methods: This was a cross-sectional study involving 219 banking staff randomly selected from five commercial banking institutions in Accra, Ghana. Demographic data was collected with a structured questionnaire. Physical inactivity was assessed using the Global Physical Activity Questionnaire. Study associations were determined using univariate analysis, and multivariate logistic regression models with adjusted odds ratio (AOR) and 95% confidence intervals (CI) estimated. Results: Of the 219 participants studied, the male to female ratio was 1.3:1.0 and the mean age(± SD) was 40.0±7.9 years. Overall, 165 (75.3%) of the study participants indulged in some form of physical activity, however, only 40 (18.3%) achieved the recommended levels. Physical inactivity was observed in 179 (81.7%) participants. The following were independently associated with physical inactivity: travel-related activities (AOR, 0.151; 95% CI, 0.059-0.384; p<0.001); working in the bank for 6-10 years (AOR, 4.617; 95% CI, 1.590-13.405; p=0.005); and working in the bank for 11 years and above (AOR, 2.816; 95% CI, 1.076-7.368; p=0.035). Conclusion: Physical inactivity was very high among bankers. Travel-related activities and working at the bank for more than six years were associated with physical inactivity. Thus, promoting regular physical activity, frequent monitoring, and implementation of other appropriate healthy lifestyle intervention strategies are vital to reduce risk of early onset disease conditions associated with physical inactivity in this population.

The authors have declared no competing interest.

The authors received no specific funding for this work

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Not Applicable

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

This study received ethical clearance from the Ghana Health Service Ethics Review Committee (GHS-ERC011/05/15).

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Not Applicable

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Not Applicable

I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

Not Applicable

It will be made available on request