Optimized Infliximab Induction Predicts Better Long-Term Clinical and Biomarker Outcomes Compared to Standard Induction Dosing

From the *Division of Gastroenterology, Hepatology and Nutrition, BC Children’s Hospital and BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, Canada

the †Department of Paediatric Gastroenterology, Hepatology and Nutrition, Royal Hospital for Children, Glasgow, United Kingdom

the ‡Department of Paediatric Gastroenterology, Hepatology and Nutrition, Royal Hospital for Children & Young People, Edinburgh, United Kingdom.

Received December 1, 2021; accepted July 25, 2022.

Sources of Funding: R.E.H., V.G., L.C., L.G., R.T., R.H., R.K.R. were supported by the Catherine McEwan Foundation. R.H. and R.K.R. were supported by NHS Research Scotland Senior Research Fellowships. K.J. was supported by the BC Children’s Hospital Research Institute Clinician Scientist Awards Program. S.L. was supported by the Hudson Scholars Awards Program.

S.L. is an advisory board member and is on the speaker’s bureau of AbbVie, Takeda. V.G. received speaker’s fees from Ferring and conference fees from AbbVie. L.C. received conference fees from Ferring, Tillots and accommodation and travel fees from Ferring. L.G. received consultancy fees from Lilly. K.J. received research grant from Janssen, AbbVie, adMare Bioinnovations and is an advisory boards member of Janssen, AbbVie, Merck, Mylan Inc. and speaker’s bureau of Abbvie. R.K.R. received speaker’s fees, travel support, advisory boards from Nestle, AbbVie, Dr Falk, Takeda, Napp, Mead Johnson, Nutricia.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal’s Web site (www.jpgn.org).

Address correspondence and reprint requests to Sally Lawrence, Division of Pediatric Gastroenterology, Hepatology and Nutrition. BC Children’s Hospital, UBC, 4480 Oak Street, Vancouver, BC V6H3V4, Canada (e-mail: [email protected]).

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