Iridium(III) complexes
Endoplasmic reticulum stress
Mitochondrial pathway
Apoptosis
Western blot analysis
AbbreviationsBakhomologous antagonist killer
BBIP2-(7-bromo-2H-benzo[d]imidazole-4-yl)-1H-imidazo[4,5-f][1,10]phenanthroline)
BEL-7402human hepatocellular
BaxBcl-2 associated x protein
CCCPcarbonylcyanide-m-chlorophenylhydrazone
Calcein-AMcalcein-acetoxymethylester
DAPI4′,6-diamidino-2-phenylindole
Caspase 3cysteinyl aspartate specific proteinase-3
dmb4,4′-dimethyl-2,2′-bipyridine
DMEMDulbecco's Modified Eagle Medium
dmp2,9-dimethyl-1,10-phenanthroline
DCHF2′,7′-dichloro-3,6-fluorandiol
DCHF-DA2′,7′-dichlorodihy-drofluorescein diacetate
DAMPsdamage-associated molecular patterns
ECLenhanced chemiluminescence
FITCfluorescein isothiocyanate
Flu-3 AMFluo-3-pentaacetoxymethyl ester
HepG2human hepatocellular carcinoma
HeLahuman cervical cancer cells
HMSPIP2-(4-(methylsulfonyl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline
IC5050% inhibition of cell growth
JC-15,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide
LO2human normal liver cells
m-TORmammalian target of rapamycin
MMPmitochondrial membrane potential
MitoTracker® Deep Red FM2′,7′-dichlorodihydro-fluorescein diacetate
MTT3-(4,5-dimethylthiazole)-2,5-diphenyltetraazolium bromide
PARPpoly ADP-ribose polymerase
PBSphosphate buffer saline
PCCPearson's colocalization coefficients
phen1,10-phenanthrolineRNase, ribonuclease
PI3Kphosphatidylinositol 3-kinase
PMSFphenylmethylsulfonyl fluoride
P-mTORphosphorylated mammalian target of rapamycin
RIPA 50mM Tris (pH 7.4), 150 mM NaCl, 1% NP-40, 0.5% sodium deoxycholate
ROSreactive oxygen species
RPMI 1640Roswell Park Memorial Institute 1640
TBST20 mM Tris-HCl, 150 mM NaCl, 0.05% Tween 20, pH 8.0
TFPIP2-(4′-trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-imidazo[4,5-f][1,10]phenanthroline)
Tristris(hydroxymethyl)aminomethane
Tweenpolyoxyethylene monolaura
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