Barta, J. A., Powell, C. A. & Wisnivesky, J. P. Global Epidemiology of Lung Cancer. Ann Glob Health 85, 8 (2019).

Ferlay, J. et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer 136, E359–E386 (2015).

Article  CAS  PubMed  Google Scholar 

Lövgren, M., Leveälahti, H., Tishelman, C., Runesdotter, S. & Hamberg, K. Time spans from first symptom to treatment in patients with lung cancer-the influence of symptoms and demographic characteristics. Acta Oncol. 47, 397–405 (2008).

Article  PubMed  Google Scholar 

Dalton, S. O., Olsen, M. H., Johansen, C., Olsen, J. H. & Andersen, K. K. Socioeconomic inequality in cancer survival - changes over time. A population-based study, Denmark, 1987–2013. Acta Oncol. 58, 737–744 (2019).

Article  PubMed  Google Scholar 

Dalton, S. O. et al. Socioeconomic position and survival after lung cancer: Influence of stage, treatment and comorbidity among Danish patients with lung cancer diagnosed in 2004–2010. Acta Oncol. 54, 797–804 (2015).

Article  PubMed  Google Scholar 

Okoli, G. N., Kostopoulou, O. & Delaney, B. C. Is symptom-based diagnosis of lung cancer possible? A systematic review and meta-analysis of symptomatic lung cancer prior to diagnosis for comparison with real-time data from routine general practice. PLoS One 13, e0207686 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Athey, V. L., Walters, S. J. & Rogers, T. K. Symptoms at lung cancer diagnosis are associated with major differences in prognosis. Thorax 73, 1177–1181 (2018).

Article  PubMed  Google Scholar 

Mortensen, J. Tidlig opsporing af kræft: symptomkendskab og lægesøgning (Early detection of cancer: symptom awareness and healthcare-seeking behavior). (Danish Cancer Society, Danish Cancer Society, 2019).

Pescosolido, B. A. Beyond rational choice: the social dynamics of how people seek help. Am. J. Sociol. 97, 1096–1138 (1992).

Article  Google Scholar 

Elnegaard, S. et al. Self-reported symptoms and healthcare seeking in the general population-exploring “The Symptom Iceberg”. BMC Public Health 15, 685 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Sele, L. M., Elnegaard, S., Balasubramaniam, K., Søndergaard, J. & Jarbøl, D. E. Lifestyle factors and contact to general practice with respiratory alarm symptoms-a population-based study. BMC Fam. Pr. 17, 47 (2016).

Article  Google Scholar 

Balasubramaniam, K. et al. Lifestyle, socioeconomic status and healthcare seeking among women with gynaecological cancer alarm symptoms: a combined questionnaire-based and register-based population study. BMJ Open 8, e021815 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Friedemann Smith, C., Whitaker, K. L., Winstanley, K. & Wardle, J. Smokers are less likely than non-smokers to seek help for a lung cancer ‘alarm’ symptom. Thorax 71, 659–661 (2016).

Article  CAS  PubMed  Google Scholar 

Walabyeki, J. et al. Experience of, awareness of and help-seeking for potential cancer symptoms in smokers and non-smokers: a cross-sectional study. PLoS One 12, e0183647 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Danish Cancer Society. Kræft i Danmark 2020 (Cancer in Denmark 2020). Vol. 1 92 Danish Cancer Society, Denmark, 2020. https://www.cancer.dk/dyn/resources/File/file/0/8830/1599042887/kraeft-i-danmark_2020.pdf.

Hoffman, R. M., Atallah, R. P., Struble, R. D. & Badgett, R. G. Lung cancer screening with low-dose CT: a meta-analysis. J. Gen. Intern Med. 35, 3015–3025 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Darrason, M., Grolleau, E., De Bermont, J. & Couraud, S. UKLS trial: looking beyond negative results. Lancet Regional Health - Eur. 10, 100184 (2021).

Article  Google Scholar 

Pinsky, P. F., Bellinger, C. R. & Miller, D. P. Jr. False-positive screens and lung cancer risk in the National Lung Screening Trial: implications for shared decision-making. J. Med. Screen 25, 110–112 (2018).

Article  PubMed  Google Scholar 

Rasmussen, J. F., Siersma, V., Malmqvist, J. & Brodersen, J. Psychosocial consequences of false positives in the Danish Lung Cancer CT Screening Trial: a nested matched cohort study. BMJ Open 10, e034682 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Danish Health and Medicines Authority. Forslag om nyt nationalt screeningsprogram (Proposal for an new national screening program). https://www.sst.dk/media/Opgaver/Forebyggelse/Screening/Ans%C3%B8gning-om-screeningsprogram/Ansoegningsskema-til-forslag-om-nyt-nationalt-screeningsprogram2.ashx?la=da&hash=AE040ED48D62398691ABD6215FEB4DDD7001B6C2#:~:text=Introduktion%20Nationale%20screeningsprogrammer%20har%20til,der%20som%20udgangspunkt%20er%20raske (2021).

Aberle, D. R. et al. The National Lung Screening Trial: overview and study design. Radiology 258, 243–253 (2011).

Article  PubMed  Google Scholar 

Bradley, S. H., Kennedy, M. P. T. & Neal, R. D. Recognising lung cancer in primary care. Adv. Ther. 36, 19–30 (2019).

Article  PubMed  Google Scholar 

Forrest, L. F., Sowden, S., Rubin, G., White, M. & Adams, J. Socio-economic inequalities in stage at diagnosis, and in time intervals on the lung cancer pathway from first symptom to treatment: systematic review and meta-analysis. Thorax 72, 430–436 (2017).

Article  PubMed  Google Scholar 

Tetzlaff, F., Epping, J., Tetzlaff, J., Golpon, H. & Geyer, S. Socioeconomic inequalities in lung cancer - a time trend analysis with German health insurance data. BMC Public Health 21, 538 (2021).

Article  PubMed  PubMed Central  Google Scholar 

McCutchan, G. M., Wood, F., Edwards, A., Richards, R. & Brain, K. E. Influences of cancer symptom knowledge, beliefs and barriers on cancer symptom presentation in relation to socioeconomic deprivation: a systematic review. BMC Cancer 15, 1000 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Scott, N., Crane, M., Lafontaine, M., Seale, H. & Currow, D. Stigma as a barrier to diagnosis of lung cancer: patient and general practitioner perspectives. Prim. Health Care Res Dev. 16, 618–622 (2015).

Article  PubMed  Google Scholar 

Scott, N. et al. Knowledge, attitudes and beliefs about lung cancer in three culturally and linguistically diverse communities living in Australia: a qualitative study. Health Promot J. Austr 25, 46–51 (2014).

Article  PubMed  Google Scholar 

Carter-Harris, L. Lung cancer stigma as a barrier to medical help-seeking behavior: practice implications. J. Am. Assoc. Nurse Pr. 27, 240–245 (2015).

Article  Google Scholar 

Carter-Harris, L., Hermann, C. P., Schreiber, J., Weaver, M. T. & Rawl, S. M. Lung cancer stigma predicts timing of medical help-seeking behavior. Oncol. Nurs. Forum 41, E203–E210 (2014).

Article  PubMed  PubMed Central  Google Scholar 

Cassim, S. et al. Patient and carer perceived barriers to early presentation and diagnosis of lung cancer: a systematic review. BMC Cancer 19, 25 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Kotecha, J. et al. Evaluating the delay prior to primary care presentation in patients with lung cancer: a cohort study. BJGP Open 5, BJGPO.2020.0130 (2021).

Forbes, L. J. et al. Differences in cancer awareness and beliefs between Australia, Canada, Denmark, Norway, Sweden and the UK (the International Cancer Benchmarking Partnership): do they contribute to differences in cancer survival? Br. J. Cancer 108, 292–300 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sele, L. M., Balasubramaniam, K., Elnegaard, S., Søndergaard, J. & Jarbøl, D. E. Lifestyle factors and experience of respiratory alarm symptoms in the general population. BMJ Open Respir. Res. 2, e000101 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Elliott, A. M., McAteer, A. & Hannaford, P. C. Revisiting the symptom iceberg in today’s primary care: results from a UK population survey. BMC Fam. Pr. 12, 16 (2011).

Article  Google Scholar 

Andersen, R. S., Paarup, B., Vedsted, P., Bro, F. & Soendergaard, J. ‘Containment’ as an analytical framework for understanding patient delay: a qualitative study of cancer patients’ symptom interpretation processes. Soc. Sci. Med. 71, 378–385 (2010).

Article  PubMed  Google Scholar 

Rasmussen, S. et al. The Danish Symptom Cohort: questionnaire and feasibility in the nationwide study on symptom experience and healthcare-seeking among 100,000 individuals. Int. J. Fam. Med. 2014, 187280 (2014).

Google Scholar 

Fielding-Singh, P., Vogel, E. A. & Prochaska, J. J. Occupying multiple stigmatized identities: smoking and unemployment stigmas among the unemployed. SSM Popul. Health 11, 100598 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Maguire, R. et al. Lung cancer stigma: a concept with consequences for patients. Cancer Rep. (Hoboken) 2, e1201 (2019).

Google Scholar 

Woo, S., Zhou, W. & Larson, J. L. Stigma experiences in people with chronic obstructive pulmonary disease: an integrative review. Int J. Chron. Obstruct Pulmon Dis. 16, 1647–1659 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Power, E. & Wardle, J. Change in public awareness of symptoms and perceived barriers to seeing a doctor following be clear on cancer campaigns in England. Br. J. Cancer 112, S22–S26 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Jarbøl, D. E. et al. Barriers to contacting general practice with alarm symptoms of colorectal cancer: a population-based study. Fam. Pr. 35, 399–405 (2018).

Article  Google Scholar 

Balasubramaniam, K. et al. Women’s barriers for contacting general practice when experiencing gynecological cancer symptoms: a population-based study. BMC Fam. Pr. 22, 167 (2021).

Article  Google Scholar 

Hvidberg, L., Wulff, C. N., Pedersen, A. F. & Vedsted, P. Barriers to healthcare seeking, beliefs about cancer and the role of socio-economic position. A Danish population-based study. Prev. Med. 71, 107–113 (2015).

Article  PubMed  Google Scholar 

Donnelly, C. et al. Do perceived barriers to clinical presentation affect anticipated time to presenting with cancer symptoms: an ICBP study. Eur. J. Public Health 27, 808–813 (2017).

Article