Available online 3 November 2022

A 46-year-old female patient whose main medical history included obesity, endometriosis, anxiety and depression was seen for absence seizures as well as Alice in Wonderland syndrome with space distortions. She also presented almost daily headaches and early cognitive impairment. Neuropsychological assessment highlighted difficulties in episodic memory, visuoconstruction abilities, and lexical processing. The Mini-Mental State Examination (MMSE) score was 25/30.

Brain imaging revealed frontal

Hyperostosis frontalis interna (HFI) is an uncommon condition characterized by excess bone growth with multiple nodules mostly on the inner table of the frontal bone. Women are more affected than men and the incidence has grown over the last centuries [1]. HFI was first described in 1719 by Giovanni Battista Morgagni, who noticed, during an autopsy, an association between a thickening of the frontal bone and both obesity and hirsutism. In 1928 Stewart and Morel added the neuropsychiatric

The authors declare that they have no competing interest.

We report the case of a female patient with rare Morgani-Stewart-Morel syndrome and neuropsychiatric symptoms where brain imaging led to the diagnosis.

There are more references available in the full text version of this article.

© 2022 Elsevier Masson SAS. All rights reserved.