Horowitz M, Maddox AF, Wishart JM, Harding PE, Chatterton BE, Shearman DJ (1991) Relationships between oesophageal transit and solid and liquid gastric emptying in diabetes mellitus. Eur J Nucl Med 18(4):229–234. https://doi.org/10.1007/BF00186645
Article CAS PubMed Google Scholar
Horowitz M, Harding PE, Maddox AF et al (1989) Gastric and oesophageal emptying in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 32(3):151–159. https://doi.org/10.1007/BF00265086
Rayner CK, Jones KL, Horowitz M (2021) Chapter 18 - Diabetic gastroparesis. In: McCallum RW, Parkman HP (eds) Gastroparesis. Academic Press: 237–253. https://doi.org/10.1016/B978-0-12-818586-5.00018-1
Watson LE, Xie C, Wang X et al (2019) Gastric emptying in patients with well-controlled type 2 diabetes compared with young and older control subjects without diabetes. J Clin Endocrinol Metab 104(8):3311–3319. https://doi.org/10.1210/jc.2018-02736
Xie C, Huang W, Wang X et al (2021) Gastric emptying in health and type 2 diabetes: An evaluation using a 75 g oral glucose drink. Diabetes Res Clin Pract 171:108610. https://doi.org/10.1016/j.diabres.2020.108610
Article CAS PubMed Google Scholar
Phillips LK, Deane AM, Jones KL, Rayner CK, Horowitz M (2015) Gastric emptying and glycaemia in health and diabetes mellitus. Nat Rev Endocrinol 11(2):112–128. https://doi.org/10.1038/nrendo.2014.202
Marathe CS, Horowitz M, Trahair LG et al (2015) Relationships of early and late glycemic responses with gastric emptying during an oral glucose tolerance test. J Clin Endocrinol Metab 100(9):3565–3571. https://doi.org/10.1210/JC.2015-2482
Article CAS PubMed Google Scholar
Jones KL, Horowitz M, Wishart MJ, Maddox AF, Harding PE, Chatterton BE (1995) Relationships between gastric emptying, intragastric meal distribution and blood glucose concentrations in diabetes mellitus. J Nucl Med 36(12):2220–2228
Wang X, Xie C, Marathe CS et al (2020) Disparities in gastric emptying and postprandial glycaemia between Han Chinese and Caucasians with type 2 diabetes. Diabetes Res Clin Pract 159:107951. https://doi.org/10.1016/j.diabres.2019.107951
Article CAS PubMed Google Scholar
Phillips WT (2006) Gastric emptying in ethnic populations: possible relationship to development of diabetes and metabolic syndrome. Ethn Dis 16(3):682–692
Goyal RK (2021) Gastric emptying abnormalities in diabetes mellitus. N Engl J Med 384(18):1742–1751. https://doi.org/10.1056/NEJMra2020927
Article CAS PubMed Google Scholar
Marathe CS, Rayner CK, Bound M et al (2014) Small intestinal glucose exposure determines the magnitude of the incretin effect in health and type 2 diabetes. Diabetes 63(8):2668–2675. https://doi.org/10.2337/db13-1757
Article CAS PubMed Google Scholar
Zhang X, Young RL, Bound M et al (2019) Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes. Diabetes Care 42(4):520–528. https://doi.org/10.2337/dc18-2156
Article CAS PubMed Google Scholar
Schol J, Wauters L, Dickman R et al (2021) United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis. United European Gastroenterol J 9(7):883–884. https://doi.org/10.1002/ueg2.12090
Article CAS PubMed PubMed Central Google Scholar
Abell TL, Camilleri M, Donohoe K et al (2008) Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine. J Nucl Med Technol 36(1):44–54. https://doi.org/10.2967/jnmt.107.048116
Trahair LG, Nauck MA, Wu T et al (2022) Measurement of gastric emptying using a 13C-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes. Exp Clin Endocrinol Diabetes https://doi.org/10.1055/a-1784-6185
Horowitz M, Rayner CK, Marathe CS, Wu T, Jones KL (2020) Glucagon-like peptide-1 receptor agonists and the appropriate measurement of gastric emptying. Diabetes Obes Metab 22(12):2504–2506. https://doi.org/10.1111/dom.14166
Article CAS PubMed Google Scholar
Bartholome R, Salden B, Vrolijk MF et al (2015) Paracetamol as a post prandial marker for gastric emptying, a food-drug interaction on absorption. PLoS One 10(9):0136618. https://doi.org/10.1371/journal.pone.0136618
Du YT, Rayner CK, Jones KL, Talley NJ, Horowitz M (2018) Gastrointestinal symptoms in diabetes: prevalence, assessment, pathogenesis, and management. Diabetes Care 41(3):627–637. https://doi.org/10.2337/dc17-1536
Article CAS PubMed Google Scholar
Jalleh RJ, Wu T, Jones KL, Rayner CK, Horowitz M, Marathe CS (2022) Relationships of glucose, GLP-1 and insulin secretion with gastric emptying after a 75g glucose load in type 2 diabetes. J Clin Endocrinol Metab. https://doi.org/10.1210/clinem/dgac330
Bergman M, Jagannathan R, Buysschaert M et al (2018) Lessons learned from the 1-hour post-load glucose level during OGTT: Current screening recommendations for dysglycaemia should be revised. Diabetes Metab Res Rev 34(5):2992. https://doi.org/10.1002/dmrr.2992
Perano SJ, Rayner CK, Kritas S et al (2015) Gastric emptying is more rapid in adolescents with type 1 diabetes and impacts on postprandial glycemia. J Clin Endocrinol Metab 100(6):2248–2253. https://doi.org/10.1210/jc.2015-1055
Vinik A, Nakave A, Chuecos Mdel P (2008) A break in the brake mechanism in diabetes: a cause of postprandial hyperglycemia. Diabetes Care 31(12):2410–2413. https://doi.org/10.2337/dc08-1694
Article PubMed PubMed Central Google Scholar
Kuwelker S, Muthyala A, O'Connor M, Bharucha AE (2020) Clinical features and disturbances of gastrointestinal transit in patients with rapid gastric emptying. Neurogastroenterol Motil 32(4):13779. https://doi.org/10.1111/nmo.13779
Chang J, Russo A, Bound M, Rayner CK, Jones KL, Horowitz M (2012) A 25-year longitudinal evaluation of gastric emptying in diabetes. Diabetes Care 35(12):2594–2596. https://doi.org/10.2337/dc12-0028
Article PubMed PubMed Central Google Scholar
Aigner L, Becker B, Gerken S, Quast DR, Meier JJ, Nauck MA (2021) Day-to-day variations in fasting plasma glucose do not influence gastric emptying in subjects with type 1 diabetes. Diabetes Care 44(2):479–488. https://doi.org/10.2337/dc20-1660
Article CAS PubMed Google Scholar
Marathe CS, Marathe JA, Rayner CK, Kar P, Jones KL, Horowitz M (2019) Hypoglycaemia and gastric emptying. Diabetes Obes Metab 21(3):491–498. https://doi.org/10.1111/dom.13570
Nauck MA, Quast DR, Wefers J, Pfeiffer AFH (2021) The evolving story of incretins (GIP and GLP-1) in metabolic and cardiovascular disease: A pathophysiological update. Diabetes Obes Metab 23(Suppl 3):5–29. https://doi.org/10.1111/dom.14496
Article CAS PubMed Google Scholar
Pilichiewicz AN, Chaikomin R, Brennan IM et al (2007) Load-dependent effects of duodenal glucose on glycemia, gastrointestinal hormones, antropyloroduodenal motility, and energy intake in healthy men. Am J Physiol Endocrinol Metab 293(3):743–753. https://doi.org/10.1152/ajpendo.00159.2007
Xie C, Huang W, Watson LE et al (2022) Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes - impact on gastric emptying. J Clin Endocrinol Metab 107(4):1643–1652. https://doi.org/10.1210/clinem/dgab828
Deane AM, Nguyen NQ, Stevens JE et al (2010) Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia. J Clin Endocrinol Metab 95(1):215–221. https://doi.org/10.1210/jc.2009-1503
Article CAS PubMed Google Scholar
Perano SJ, Couper JJ, Horowitz M et al (2014) Pancreatic enzyme supplementation improves the incretin hormone response and attenuates postprandial glycemia in adolescents with cystic fibrosis: a randomized crossover trial. J Clin Endocrinol Metab 99(7):2486–2493. https://doi.org/10.1210/jc.2013-4417
Article CAS PubMed Google Scholar
Menge BA, Schrader H, Breuer TG et al (2009) Metabolic consequences of a 50% partial pancreatectomy in humans. Diabetologia 52(2):306–317. https://doi.org/10.1007/s00125-008-1219-1
Article CAS PubMed Google Scholar
Linnebjerg H, Park S, Kothare PA et al (2008) Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes. Regul Pept 151(1–3):123–129. https://doi.org/10.1016/j.regpep.2008.07.003
Jones KL, Rigda RS, Buttfield MDM et al (2019) Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes. Diabetes Obes Metab 21(5):1158–1167. https://doi.org/10.1111/dom.13633
Article CAS PubMed Google Scholar
Rayner CK, Watson LE, Phillips LK et al (2020) Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: A randomized controlled trial. Diabetes Care 43(8):1813–1821. https://doi.org/10.2337/dc20-0190
Article CAS PubMed Google Scholar
Meier JJ, Rosenstock J, Hincelin-Mery A et al (2015) Contrasting effects of lixisenatide and liraglutide on postprandial glycemic control, gastric emptying, and safety parameters in patients with type 2 diabetes on optimized insulin glargine with or without metformin: a randomized, open-label trial. Diabetes Care 38(7):1263–1273. https://doi.org/10.2337/dc14-1984
Article CAS PubMed Google Scholar
Lorenz M, Pfeiffer C, Steinstrasser A et al (2013) Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia. Regul Pept 185:1–8. https://doi.org/10.1016/j.regpep.2013.04.001
Article CAS PubMed Google Scholar
Dahl K, Brooks A, Almazedi F, Hoff ST, Boschini C, Baekdal TA (2021) Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes Obes Metab 23(7):1594–1603. https://doi.org/10.1111/dom.14373
Article CAS PubMed PubMed Central Google Scholar
Hjerpsted JB, Flint A, Brooks A, Axelsen MB, Kvist T, Blundell J (2018) Semaglutide improves postprandial glucose and lipid metabolism, and delays first-hour gastric emptying in subjects with obesity. Diabetes Obes Metab 20(3):610–619. https://doi.org/10.1111/dom.13120
Urva S, Coskun T, Loghin C et al (2020) The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists. Diabetes Obes Metab 22(10):1886–1891. https://doi.org/10.1111/dom.14110
Article CAS PubMed PubMed Central Google Scholar
Drucker DJ, Buse JB, Taylor K et al (2008) Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 372(9645):1240–1250. https://doi.org/10.1016/S0140-6736(08)61206-4
Article CAS PubMed Google Scholar
Barrington P, Chien JY, Showalter HD et al (2011) A 5-week study of the pharmacokinetics and pharmacodynamics of LY2189265, a novel, long-acting glucagon-like peptide-1 analogue, in patients with type 2 diabetes. Diabetes Obes Metab 13(5):426–433. https://doi.org/10.1111/j.1463-1326.2011.01364.x
留言 (0)