Following the PRISMA guidelines, 365 articles were included initially. Due to duplication, 189 studies were excluded. Following the screening of titles and abstracts, 46 articles were obtained for full-text inspection. And a total of 36 articles7, 8, 9,11, 12, 13,18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47 met all eligibility criteria for this review. All the trials evaluated the effects of hemostasis before and after