Al-Bari M, Alim A (2020) A current view of molecular dissection in autophagy machinery. J Physiol Biochem 76:357–372

PubMed  Google Scholar 

Amati-Bonneau P, Milea D, Bonneau D, Chevrollier A, Ferré M, Guillet V, Gueguen N, Loiseau D, de Crescenzo MAP, Verny C (2009) OPA1-associated disorders: phenotypes and pathophysiology. Int J Biochem Cell Biol 41:1855–1865

CAS  PubMed  Google Scholar 

Ambivero CT, Cilenti L, Main S, Zervos AS (2014) Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP. Cell Signal 26:2921–2929

CAS  PubMed  Google Scholar 

Beach TG, Walker R, McGeer E (1989) Patterns of gliosis in Alzheimer’s disease and aging cerebrum. Glia 2:420–436

CAS  PubMed  Google Scholar 

Biskup S, Moore DJ, Celsi F, Higashi S, West AB, Andrabi SA, Kurkinen K, Yu SW, Savitt JM, Waldvogel HJ (2006) Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann Neurol 60:557–569

CAS  PubMed  Google Scholar 

Blackinton J, Lakshminarasimhan M, Thomas KJ, Ahmad R, Greggio E, Raza AS, Cookson MR, Wilson MA (2009) Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. J Biol Chem 284:6476–6485

CAS  PubMed  PubMed Central  Google Scholar 

Cai Q, Jeong YY (2020) Mitophagy in Alzheimer’s disease and other age-related neurodegenerative diseases. Cells 9:150

CAS  PubMed Central  Google Scholar 

Castillo K, Nassif M, Valenzuela V, Rojas F, Matus S, Mercado G, Court FA, van Zundert B, Hetz C (2013) Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Autophagy 9:1308–1320

CAS  PubMed  Google Scholar 

Catalán García M (2017) Mitochondrial profile and amyloidogenic molecules in sporadic inclusion body myositis. Universitat de Barcelona

Google Scholar 

Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A (2020) Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model. Nat Commun 11:1–13

Google Scholar 

Chen Y, Liu H, Guan Y, Wang Q, Zhou F, Jie L, Ju J, Pu L, Du H, Wang X (2015) The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis. Am J Trans Res 7:1574

CAS  Google Scholar 

Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D (2013) Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nat Cell Biol 15:1197–1205

CAS  PubMed  PubMed Central  Google Scholar 

Correia SC, Perry G, Moreira PI (2016) Mitochondrial traffic jams in Alzheimer’s disease-pinpointing the roadblocks. Biochim Biophys Acta (BBA)-Mol Basis Dis 1862:1909–1917

CAS  Google Scholar 

Crews L, Rockenstein E, Masliah E (2010) APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis. Brain Struct Funct 214:111–126

CAS  PubMed  Google Scholar 

Dagda RK, Cherra SJ, Kulich SM, Tandon A, Park D, Chu CT (2009) Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem 284:13843–13855

CAS  PubMed  PubMed Central  Google Scholar 

Deas E, Wood NW, Plun-Favreau H (2011) Mitophagy and Parkinson’s disease: the PINK1–parkin link. Biochim Biophys Acta (BBA)-Mol Cell Res 1813:623–633

CAS  Google Scholar 

DeKosky ST, Scheff SW (1990) Synapse loss in frontal cortex biopsies in Alzheimer’s disease: correlation with cognitive severity. Ann Neurol 27:457–464

CAS  PubMed  Google Scholar 

DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel J, Aronin N (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277:1990–1993

CAS  PubMed  Google Scholar 

Dong R, Saheki Y, Swarup S, Lucast L, Harper JW, De Camilli P (2016) Endosome-ER contacts control actin nucleation and retromer function through VAP-dependent regulation of PI4P. Cell 166:408–423

CAS  PubMed  PubMed Central  Google Scholar 

Evans CS, Holzbaur EL (2019) Autophagy and mitophagy in ALS. Neurobiol Dis 122:35–40

CAS  PubMed  Google Scholar 

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X (2019) Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease. Nat Neurosci 22:401–412

CAS  PubMed  PubMed Central  Google Scholar 

Fivenson EM, Lautrup S, Sun N, Scheibye-Knudsen M, Stevnsner T, Nilsen H, Bohr VA, Fang EF (2017) Mitophagy in neurodegeneration and aging. Neurochem Int 109:202–209

CAS  PubMed  PubMed Central  Google Scholar 

Fleming A, Bourdenx M, Fujimaki M, Karabiyik C, Krause GJ, Lopez A, Martín-Segura A, Puri C, Scrivo A, Skidmore J (2022) The different autophagy degradation pathways and neurodegeneration. Neuron 110:935

CAS  PubMed  Google Scholar 

Follett J, Bugarcic A, Yang Z, Ariotti N, Norwood SJ, Collins BM, Parton RG, Teasdale RD (2016) Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation. J Biol Chem 291:18283–18298

CAS  PubMed  PubMed Central  Google Scholar 

Franco-Iborra S, Plaza-Zabala A, Montpeyo M, Sebastian D, Vila M, Martinez-Vicente M (2021) Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy 17:672–689

CAS  PubMed  Google Scholar 

Franco-Iborra S, Vila M, Perier C (2018) Mitochondrial quality control in neurodegenerative diseases: focus on Parkinson’s disease and Huntington’s disease. Front Neurosci 12:342

PubMed  PubMed Central  Google Scholar 

Gao H, Yang W, Qi Z, Lu L, Duan C, Zhao C, Yang H (2012) DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy. J Mol Biol 423:232–248

CAS  PubMed  Google Scholar 

Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Leßmann V, Humbert S (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118:127–138

CAS  PubMed  Google Scholar 

Haywood AF, Staveley BE (2004) Parkin counteracts symptoms in a Drosophila model of Parkinson’s disease. BMC Neurosci 5:1–12

Google Scholar 

Huang B, Wu Q, Zhou H, Huang C, Xia XG (2016) Increased Ubqln2 expression causes neuron death in transgenic rats. J Neurochem 139:285–293

CAS  PubMed  PubMed Central  Google Scholar 

Huang C-Y, Sivalingam K, Shibu MA, Liao PH, Ho T-J, Kuo WW, Chen RJ, Day CH, Viswanadha VP, Ju DT (2020) Induction of autophagy by vasicinone protects neural cells from mitochondrial dysfunction and attenuates paraquat-mediated Parkinson’s disease associated α-synuclein levels. Nutrients 12(6):1707

CAS  PubMed Central  Google Scholar 

Itagaki S, McGeer P, Akiyama H, Zhu S, Selkoe D (1989) Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. J Neuroimmunol 24:173–182

CAS  PubMed  Google Scholar 

Jiang TF, Zhang YJ, Zhou HY, Wang HM, Tian LP, Liu J, Ding JQ, Chen SD (2013) Curcumin ameliorates the neurodegenerative pathology in A53T α-synuclein cell model of Parkinson’s disease through the downregulation of mTOR/p70S6K signaling and the recovery of macroautophagy. J Neuroimmune Pharmacol 8:356–369

PubMed  Google Scholar 

Johri A, Chandra A, Beal MF (2013) PGC-1α, mitochondrial dysfunction, and Huntington’s disease. Free Radical Biol Med 62:37–46

CAS  Google Scholar 

Joshi AS, Thompson MN, Fei N, Hüttemann M, Greenberg ML (2012) Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae. J Biol Chem 287:17589–17597

CAS  PubMed  PubMed Central  Google Scholar 

Kagan V, Jiang J, Huang Z, Tyurina Y, Desbourdes C, Cottet-Rousselle C, Dar H, Verma M, Tyurin V, Kapralov A (2016) NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy. Cell Death Differ 23:1140–1151

CAS  PubMed  PubMed Central  Google Scholar 

Kamat PK, Kalani A, Kyles P, Tyagi SC, Tyagi N (2014) Autophagy of mitochondria: a promising therapeutic target for neurodegenerative disease. Cell Biochem Biophys 70:707–719

CAS  PubMed  PubMed Central  Google Scholar 

Kapogiannis D, Mattson MP (2011) Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer’s disease. Lancet Neurol 10:187–198

CAS  PubMed  Google Scholar 

Kim H, Cho M, Shim W, Kim J, Jeon E, Kim D, Yoon S (2017) Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects. Mol Psychiatry 22:1576–1584

CAS  PubMed  Google Scholar 

Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:605–608

CAS  PubMed  Google Scholar 

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M (2012) PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2:120080

PubMed  PubMed Central  Google Scholar 

Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, Behl C, Terzic J, Dikic I (2013) Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J Cell Sci 126:580–592

CAS  PubMed  Google Scholar 

Krebiehl G, Ruckerbauer S, Burbulla LF, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich FN, Woitalla D (2010) Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson’s disease-associated protein DJ-1. PLoS ONE 5:e9367

PubMed