No seasonality in multiple sclerosis risk near the Equator

Risk of multiple sclerosis (MS) has been shown to have seasonal variation, with prevalence being highest among individuals born in spring and lowest in those born in autumn, compared with the general population. Variations in exposure to sunlight and UV radiation during pregnancy are thought to be the underlying cause of this phenomenon. Indeed, research has indicated a more pronounced difference between months of birth in regions with higher latitude compared with lower latitude, which could be attributed to the larger seasonal contrast in sunlight exposure in regions further from the Equator.

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