CC BY-NC-ND 4.0 · South Asian J Cancer
DOI: 10.1055/s-0042-1757426
Vasudeva K. Bhat
1 Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India
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1 Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India
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Nawaz Usman
2 Department of Surgical Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India
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2 Department of Surgical Oncology, Manipal Comprehensive Cancer Care Center, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India
› Author Affiliations Funding This study did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.Primary malignant germ cell tumor (GCT) of the mediastinum is a rare entity with an incidence ranging from 1 to 2% of all childhood cancers. Though a few cases of bone metastasis from mediastinal GCTs have been reported, synchronous whole sternal metastasis from primary malignant mediastinal GCTs is very rare. We report such a rare manifestation in a teenager, emphasizing the need for a multidisciplinary treatment approach with neoadjuvant chemotherapy, surgical expertise for en bloc excision of the mediastinal mass along with whole sternal resection, and reconstruction in a dedicated cancer care center for better oncological outcomes.
Keywords malignant mediastinal germ cell tumor - sternal metastasis - sternal resection and reconstruction - childhood cancer Ethics ApprovalThe institutional research committee has confirmed that no ethical approval is required.
Written informed consent was obtained from the patient for participation in the study and for publication of their clinical details and images.
Publication HistoryArticle published online:
02 November 2022
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