Hewitt RJ, Lloyd CM (2021) Regulation of immune responses by the airway epithelial cell landscape. Nat Rev Immunol 21:347–362
Article CAS PubMed PubMed Central Google Scholar
Sun H, Sun C, Xiao W, Sun R (2019) Tissue-resident lymphocytes: from adaptive to innate immunity. Cell Mol Immunol 16:205–215
Article CAS PubMed PubMed Central Google Scholar
Allie SR, Bradley JE, Mudunuru U, Schultz MD, Graf BA, Lund FE, Randall TD (2019) The establishment of resident memory B cells in the lung requires local antigen encounter. Nat Immunol 20:97–108
Article CAS PubMed Google Scholar
Yuan R, Yu J, Jiao Z, Li J, Wu F, Yan R, Huang X, Chen C (2021) The roles of tissue-resident memory T cells in lung diseases. Front Immunol 12:710375
Article CAS PubMed PubMed Central Google Scholar
Ardain A, Marakalala MJ, Leslie A (2020) Tissue-resident innate immunity in the lung. Immunology 159:245–256
Article CAS PubMed Google Scholar
Evren E, Ringqvist E, Willinger T (2020) Origin and ontogeny of lung macrophages: from mice to humans. Immunology 160:126–138
Article CAS PubMed Google Scholar
Kopf M, Schneider C, Nobs SP (2015) The development and function of lung-resident macrophages and dendritic cells. Nat Immunol 16:36–44
Article CAS PubMed Google Scholar
Ginhoux F, Guilliams M (2016) Tissue-resident macrophage ontogeny and homeostasis. Immunity 44:439–449
Article CAS PubMed Google Scholar
Perdiguero EG, Geissmann F (2016) The development and maintenance of resident macrophages. Nat Immunol 17:2–8
Article CAS PubMed PubMed Central Google Scholar
Guilliams M, De Kleer I, Henri S, Post S, Vanhoutte L, De Prijck S, Deswarte K, Malissen B, Hammad H, Lambrecht BN (2013) Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J Exp Med 210:1977–1992
Article CAS PubMed PubMed Central Google Scholar
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M (2013) Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38:792–804
Article CAS PubMed Google Scholar
Schneider C, Nobs SP, Kurrer M, Rehrauer H, Thiele C, Kopf M (2014) Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages. Nat Immunol 15:1026–1037
Article CAS PubMed Google Scholar
Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel EM, Mack M, Beinke S, Wack A (2020) Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection. Nat Immunol 21:145–157
Article CAS PubMed PubMed Central Google Scholar
Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M (2019) Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol 20:163–172
Article CAS PubMed PubMed Central Google Scholar
Lechner AJ, Driver IH, Lee J, Conroy CM, Nagle A, Locksley RM, Rock JR (2017) Recruited monocytes and type 2 immunity promote lung regeneration following pneumonectomy. Cell Stem Cell 21:120–34.e7
Article CAS PubMed PubMed Central Google Scholar
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H et al (2021) The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging. J Clin Invest 131:e140299
Article CAS PubMed Central Google Scholar
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H (2017) Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. J Exp Med 214:2387–2404
Article CAS PubMed PubMed Central Google Scholar
Tan SYS, Krasnow MA (2016) Developmental origin of lung macrophage diversity. Development 143:1318–1327
CAS PubMed PubMed Central Google Scholar
Nakata K, Gotoh H, Watanabe J, Uetake T, Komuro I, Yuasa K, Watanabe S, Ieki R, Sakamaki H, Akiyama H, Kudoh S, Naitoh M, Satoh H, Shimada K (1999) Augmented proliferation of human alveolar macrophages after allogeneic bone marrow transplantation. Blood 93:667–673
Article CAS PubMed Google Scholar
Wickenhauser C, Thiele J, Pérez F, Varus E, Stoffel MS, Kvasnicka HM, Beelen DW, Schaefer UW (2002) Mixed chimerism of the resident macrophage population after allogeneic bone marrow transplantation for chronic myeloid leukemia. Transplantation 73:104–111
Eguíluz-Gracia I, Schultz HH, Sikkeland LI, Danilova E, Holm AM, Pronk CJ, Agace WW, Iversen M, Andersen C, Jahnsen FL, Baekkevold ES (2016) Long-term persistence of human donor alveolar macrophages in lung transplant recipients. Thorax 71:1006–1011
Nayak DK, Zhou F, Xu M, Huang J, Tsuji M, Hachem R, Mohanakumar T (2016) Long-term persistence of donor alveolar macrophages in human lung transplant recipients that influences donor-specific immune responses. Am J Transplant 16:2300–2311
Article CAS PubMed PubMed Central Google Scholar
Byrne AJ, Powell JE, O'Sullivan BJ, Ogger PP, Hoffland A, Cook J, Bonner KL, Hewitt RJ, Wolf S, Ghai P, Walker SA, Lukowski SW, Molyneaux PL, Saglani S, Chambers DC, Maher TM, Lloyd CM (2020) Dynamics of human monocytes and airway macrophages during healthy aging and after transplant. J Exp Med 217:e20191236
Article PubMed PubMed Central Google Scholar
Evren E, Ringqvist E, Tripathi KP, Sleiers N, Rives IC, Alisjahbana A, Gao Y, Sarhan D, Halle T, Sorini C, Lepzien R, Marquardt N, Michaelsson J, Smed-Sorensen A, Botling J, Karlsson MCI, Villablanca EJ, Willinger T (2021) Distinct developmental pathways from blood monocytes generate human lung macrophage diversity. Immunity 54(259–75):e7
Bharat A, Bhorade SM, Morales-Nebreda L, McQuattie-Pimentel AC, Soberanes S, Ridge K, DeCamp MM, Mestan KK, Perlman H, Budinger GR, Misharin AV (2016) Flow cytometry reveals similarities between lung macrophages in humans and mice. Am J Respir Cell Mol Biol 54:147–149
Article CAS PubMed PubMed Central Google Scholar
Evren E, Ringqvist E, Doisne J-M, Thaller A, Sleiers N, Flavell RA, Di Santo JP, Willinger T (2022) CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages. J Exp Med 219:e20210987
Article CAS PubMed PubMed Central Google Scholar
Misharin AV, Morales-Nebreda L, Mutlu GM, Budinger GR, Perlman H (2013) Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung. Am J Respir Cell Mol Biol 49:503–510
Article CAS PubMed PubMed Central Google Scholar
del Rio ML, Rodriguez-Barbosa JI, Kremmer E, Förster R (2007) CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. J Immunol 178:6861–6866
Demedts IK, Brusselle GG, Vermaelen KY, Pauwels RA (2005) Identification and characterization of human pulmonary dendritic cells. Am J Respir Cell Mol Biol 32:177–184
Article CAS PubMed Google Scholar
Lambrecht BN, Hammad H (2012) Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu Rev Immunol 30:243–270
Article CAS PubMed Google Scholar
Swiecki M, Omattage NS, Brett TJ (2013) BST-2/tetherin: structural biology, viral antagonism, and immunobiology of a potent host antiviral factor. Mol Immunol 54:132–139
Article CAS PubMed Google Scholar
Diefenbach A, Colonna M, Koyasu S (2014) Development, differentiation, and diversity of innate lymphoid cells. Immunity 41:354–365
Article CAS PubMed PubMed Central Google Scholar
Vivier E, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie ANJ, Mebius RE, Powrie F, Spits H (2018) Innate Lymphoid Cells: 10 Years On. Cell 174:1054–1066
留言 (0)