aDiabetes Unit, Endocrine Division, Massachusetts General Hospital

bHarvard Medical School, Boston, Massachusetts

cDivision of Endocrinology

dDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island

eBroad Institute of MIT and Harvard

fDepartment of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA

Correspondence to Daryl J. Selen, MD, 375 Wampanoag Trail, Suite 103 East Providence, RI 02915, USA. Tel: +1 401 649 4095; fax: +401 649 4092; e-mail: [email protected]