Testosterone and the Androgen Receptor

Rostom M. Ramasamy R. Kohn T.P.

History of testosterone therapy through the ages.

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The effects produced on man by subcutaneous injections of a liquid obtained from the testicles of animals.

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The role of kisspeptin neurons in reproduction and metabolism.

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Androgen-binding protein and reproduction: where do we stand?.

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Assessment of free testosterone concentration.

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Testosterone and Cardiovascular Disease.

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The relationship between sleep disorders and testosterone in men.

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The relationship between sleep disorders and testosterone.

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Testosterone Replacement Therapy in Hypogonadal Men.

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The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate.

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Characterization and expression of a cDNA encoding the human androgen receptor.

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Androgen Receptor Structure, Function and Biology: From Bench to Bedside.

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Localization of Functional Domains in the Androgen Receptor.

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The role of the polyglutamine tract in androgen receptor.

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Discovery of drugs that directly target the intrinsically disordered region of the androgen receptor.

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The role of DNA response elements as allosteric modulators of steroid receptor function.

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The hinge region in androgen receptor control.

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Amino acids 3-13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor.

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Mutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene.

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Androgen receptor action in hormone-dependent and recurrent prostate cancer.

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Prostate specific antigen gene regulation by androgen receptor.

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Androgen receptor signaling in prostate cancer.

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Androgen receptor signaling and mutations in prostate cancer.

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Dysregulated androgen synthesis and anti-androgen resistance in advanced prostate cancer.

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Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis.

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Nonclassical androgen and estrogen signaling is essential for normal spermatogenesis.

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Androgen Receptor Antagonists in Castration-Resistant Prostate Cancer.

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Estrogens in Male Physiology.

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Alternatives to Testosterone Therapy: A Review.

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