Ai Y, Liu S, Luo H, Wu S, Wei H, Tang Z et al (2021) METTL3 intensifies the progress of oral squamous cell carcinoma via modulating the m6A amount of PRMT5 and PD-L1. J Immunol Res 2021:6149558. https://doi.org/10.1155/2021/6149558

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bienkowska KJ, Hanley CJ, Thomas GJ (2021) Cancer-associated fibroblasts in oral cancer: a current perspective on function and potential for therapeutic targeting. Front Oral Health 2:686337. https://doi.org/10.3389/froh.2021.686337

Article  PubMed  PubMed Central  Google Scholar 

Chen Z, Zuo X, Zhang Y, Han G, Zhang L, Wu J, Wang X (2018) MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect. Cell Death Dis 9:549. https://doi.org/10.1038/s41419-018-0616-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen P, Hu J, Han X, Chen Y (2022) Advances in the functional roles of N6-methyladenosine modification in cancer progression: mechanisms and clinical implications. Mol Biol Rep. https://doi.org/10.1007/s11033-022-07126-5

Article  PubMed  PubMed Central  Google Scholar 

Haldar A, Singh AK (2022) The association of long non-coding RNA in the prognosis of oral squamous cell carcinoma. Genes Genomics. https://doi.org/10.1007/s13258-021-01194-w

Article  PubMed  Google Scholar 

Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ (2020) M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT. Aging 12:11667–11684. https://doi.org/10.18632/aging.103333

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang M, Xu S, Liu L, Zhang M, Guo J, Yuan Y et al (2021) m6A methylation regulates osteoblastic differentiation and bone remodeling. Front Cell Dev Biol 9:783322. https://doi.org/10.3389/fcell.2021.783322

Article  PubMed  PubMed Central  Google Scholar 

Li M, Gao F, Zhao Q, Zuo H, Liu W, Li W (2020) Tanshinone IIA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis. Cell Death Dis 11:381. https://doi.org/10.1038/s41419-020-2579-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li H, Xiao W, He Y, Wen Z, Cheng S, Zhang Y, Li Y (2021a) Novel insights into the multifaceted functions of RNA n(6)-methyladenosine modification in degenerative musculoskeletal diseases. Front Cell Dev Biol 9:766020. https://doi.org/10.3389/fcell.2021.766020

Article  PubMed  PubMed Central  Google Scholar 

Li X, Xie X, Gu Y, Zhang J, Song J, Cheng X, Gao Y, Ai Y (2021b) Fat mass and obesity-associated protein regulates tumorigenesis of arecoline-promoted human oral carcinoma. Cancer Med 10:6402–6415. https://doi.org/10.1002/cam4.4188

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu L, Wu Y, Li Q, Liang J, He Q, Zhao L et al (2020) METTL3 promotes tumorigenesis and metastasis through BMI1 m(6)A methylation in oral squamous cell carcinoma. Mol Therapy 28:2177–2190. https://doi.org/10.1016/j.ymthe.2020.06.024

Article  CAS  Google Scholar 

Metsäniitty M, Hasnat S, Salo T, Salem A (2021) Oral microbiota—a new frontier in the pathogenesis and management of head and neck cancers. Cancers. https://doi.org/10.3390/cancers14010046

Article  PubMed  PubMed Central  Google Scholar 

Mu H, Li H, Liu Y, Wang X, Mei Q, Xiang W (2022) N6-methyladenosine modifications in the female reproductive system: roles in gonad development and diseases. Int J Biol Sci 18:771–782. https://doi.org/10.7150/ijbs.66218

Article  CAS  PubMed  PubMed Central  Google Scholar 

Relier S, Rivals E, David A (2022) The multifaceted functions of the fat mass and obesity-associated protein (FTO) in normal and cancer cells. RNA Biol 19:132–142. https://doi.org/10.1080/15476286.2021.2016203

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shahoumi LA (2021) Oral cancer stem cells: therapeutic implications and challenges. Front Oral Health 2:685236. https://doi.org/10.3389/froh.2021.685236

Article  PubMed  PubMed Central  Google Scholar 

Tong H, Wei H, Smith AO, Huang J (2021) The role of m6A epigenetic modification in the treatment of colorectal cancer immune checkpoint inhibitors. Front Immunol 12:802049. https://doi.org/10.3389/fimmu.2021.802049

Article  CAS  PubMed  Google Scholar 

van der Kamp MF, Halmos GB, Guryev V, Horvatovich PL, Schuuring E, van der Laan B et al (2022) Age-specific oncogenic pathways in head and neck squamous cell carcinoma - are elderly a different subcategory? Cell Oncol (dordr). https://doi.org/10.1007/s13402-021-00655-4

Article  Google Scholar 

Wang F, Zhu Y, Cai H, Liang J, Wang W, Liao Y et al (2021) N6-methyladenosine methyltransferase METTL14-mediated autophagy in malignant development of oral squamous cell carcinoma. Front Oncol 11:738406. https://doi.org/10.3389/fonc.2021.738406

Article  PubMed  PubMed Central  Google Scholar 

Xu L, Li Q, Wang Y, Wang L, Guo Y, Yang R et al (2021) m(6)A methyltransferase METTL3 promotes oral squamous cell carcinoma progression through enhancement of IGF2BP2-mediated SLC7A11 mRNA stability. Am J Cancer Res 11:5282–5298

CAS  PubMed  PubMed Central  Google Scholar 

Zhu F, Yang T, Yao M, Shen T, Fang C (2021) HNRNPA2B1, as a m(6)A reader, promotes tumorigenesis and metastasis of oral squamous cell carcinoma. Front Oncol 11:716921. https://doi.org/10.3389/fonc.2021.716921

Article  PubMed  PubMed Central  Google Scholar