Neary D, Snowden J, Mann D (2005) Frontotemporal dementia. Lancet Neurol 4(11):771–780

Article  PubMed  Google Scholar 

Irwin DJ, Trojanowski JQ, Grossman M (2013) Cerebrospinal fluid biomarkers for differentiation of frontotemporal lobar degeneration from Alzheimer’s disease. Front Aging Neurosci 5:6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sieben A, Van Langenhove T, Engelborghs S, Martin J-J, Boon P, Cras P et al (2012) The genetics and neuropathology of frontotemporal lobar degeneration. Acta Neuropathol 124(3):353–372. https://doi.org/10.1007/s00401-012-1029-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Josephs KA, Hodges JR, Snowden JS, MacKenzie IR, Neumann M, Mann DM et al (2011) Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 122:137–153

Article  PubMed  PubMed Central  Google Scholar 

Seelaar H, Kamphorst W, Rosso SM, Azmani A, Masdjedi R, De Koning I et al (2008) Distinct genetic forms of frontotemporal dementia. Neurology 71:1220–1226

Article  CAS  PubMed  Google Scholar 

Warren JD, Rohrer JD, Rossor MN (2013) Frontotemporal dementia. BMJ 347(3):f4827–f4827. https://doi.org/10.1136/bmj.f4827

Article  PubMed  PubMed Central  Google Scholar 

Rabinovici GD, Miller BL (2010) Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 24(5):375–398

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pose M, Cetkovich M, Gleichgerrcht E, Ibáñez A, Torralva T, Manes F (2013) The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry 25:159–167

Article  PubMed  Google Scholar 

Zetterberg H, van Swieten JC, Boxer AL, Rohrer JD (2019) Review: Fluid biomarkers for frontotemporal dementias. Neuropathol Appl Neurobiol 45(1):81–87

Article  CAS  PubMed  Google Scholar 

Meeter LH, Kaat LD, Rohrer JD, Van Swieten JC (2017) Imaging and fluid biomarkers in frontotemporal dementia. Nat Rev Neurol 13:406–419

Article  CAS  PubMed  Google Scholar 

Meeter LHH, Vijverberg EG, Del Campo M, Rozemuller AJM, Donker Kaat L, de Jong FJ et al (2018) Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum. Neurology 90(14):e1231–e1239

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pijnenburg YAL, Verwey NA, van der Flier WM, Scheltens P, Teunissen CE (2015) Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes. Alzheimer’s dement diagnosis. Assess Dis Monit 1:505–512

Google Scholar 

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN et al (2010) Aptamer-based multiplexed proteomic technology for biomarker discovery. PLoS ONE 5(12):e15004

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keefe AD, Pai S, Ellington A (2010) Aptamers as therapeutics. Nat Rev Drug Discov 9(7):537–550

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O’Connell D et al (2012) Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proc Natl Acad Sci USA 109(49):19971–19976

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S et al (2014) Alzheimer’s disease biomarker discovery using SOMAscan multiplexed protein technology. Alzheimer’s Dement 10:724–734

Article  Google Scholar 

Shi L, Westwood S, Baird AL, Winchester L, Dobricic V, Kilpert F et al (2019) Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. Alzheimer’s Dement 15(11):1478–1488

Article  Google Scholar 

Westwood S, Baird AL, Hye A, Ashton NJ, Nevado-Holgado AJ, Anand SN et al (2018) Plasma protein biomarkers for the prediction of CSF amyloid and tau and [18F]-flutemetamol PET scan result. Front Aging Neurosci 10:409

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rosso SM, Kaat LD, Baks T, Joosse M, De Koning I, Pijnenburg Y et al (2003) Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 126:2016–2022

Article  PubMed  Google Scholar 

van der Flier WM, Scheltens P (2018) Amsterdam dementia cohort: performing research to optimize care. Perry G, Avila J, Tabaton M, Zhu X, editors. J Alzheimer’s Dis 62(3):1091–1111. https://doi.org/10.3233/JAD-170850

Article  Google Scholar 

Van Der Flier WM, Pijnenburg YAL, Prins N, Lemstra AW, Bouwman FH, Teunissen CE et al (2014) Optimizing patient care and research: the Amsterdam dementia cohort. J Alzheimer’s Dis 41(1):313–327

Article  Google Scholar 

Aalten P, Ramakers IHGB, Biessels GJ, de Deyn PP, Koek HL, OldeRikkert MGM et al (2014) The Dutch Parelsnoer Institute—neurodegenerative diseases; methods, design and baseline results. BMC Neurol 14:1–8

Article  Google Scholar 

McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 34(7):939–939. https://doi.org/10.1212/WNL.34.7.939

Article  CAS  PubMed  Google Scholar 

Verberk IMW, Misdorp EO, Koelewijn J, Ball AJ, Blennow K, Dage JL et al (2021) Characterization of pre-analytical sample handling effects on a panel of Alzheimer’s disease–related blood-based biomarkers: results from the standardization of Alzheimer’s blood biomarkers (SABB) working group. Alzheimer’s Dement. https://doi.org/10.1002/alz.12510

Article  Google Scholar 

Del Campo M, Hoozemans JJM, Dekkers L-L, Rozemuller AJ, Korth C, Müller-Schiffmann A et al (2014) BRI2-BRICHOS is increased in human amyloid plaques in early stages of Alzheimer’s disease. Neurobiol Aging 35(7):1596–1604

Article  PubMed  Google Scholar 

Mackenzie IRA, Neumann M, Baborie A, Sampathu DM, Du Plessis D, Jaros E et al (2011) A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol 122:111–113

Article  PubMed  PubMed Central  Google Scholar 

Lee EB, Porta S, Michael Baer G, Xu Y, Suh ER, Kwong LK et al (2017) Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration. Acta Neuropathol 134:65–78

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cairns NJ, Bigio EH, Mackenzie IRA, Neumann M, Lee VMY, Hatanpaa KJ et al (2007) Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the consortium for frontotemporal lobar degeneration. Acta Neuropathol 114:5–22

Article  PubMed  PubMed Central  Google Scholar 

Goeman JJ, Van de Geer S, De Kort F, van Houwellingen HC (2004) A global test for groups of genes: testing association with a clinical outcome. Bioinformatics 20:93–99

Article  CAS  PubMed  Google Scholar 

Ashton NJ, Hye A, Rajkumar AP, Leuzy A, Snowden S, Suárez-Calvet M et al (2020) An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders. Nat Rev Neurol 16:265–284

Article  PubMed  Google Scholar 

Teunissen CE, Elias N, Koel-Simmelink MJA, Durieux-Lu S, Malekzadeh A, Pham TV et al (2016) Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics. Alzheimer’s dement diagnosis. Assess Dis Monit 2:86–94

Google Scholar 

van der Ende EL, Meeter LH, Stingl C, van Rooij JGJ, Stoop MP, Nijholt DAT et al (2019) Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics. Ann Clin Transl Neurol 6(4):698–707. https://doi.org/10.1002/acn3.745

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dayon L, Cominetti O, Wojcik J, Galindo AN, Oikonomidi A, Henry H et al (2019) Proteomes of paired human cerebrospinal fluid and plasma: relation to blood-brain barrier permeability in older adults. J Proteome Res 18(3):1162–1174. https://doi.org/10.1021/acs.jproteome.8b00809

Article  CAS  PubMed  Google Scholar 

Whelan CD, Mattsson N, Nagle MW, Vijayaraghavan S, Hyde C, Janelidze S et al (2019) Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease. Acta Neuropathol Commun 7(1):169. https://doi.org/10.1186/s40478-019-0795-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

del Campo M, Zetterberg H, Gandy S, Onyike CU, Oliveira F, Udeh-Momoh C et al (2022) New developments of biofluid-based biomarkers for routine diagnosis and disease trajectories in frontotemporal dementia. Alzheimer’s Dement. https://doi.org/10.1002/alz.12643

Article  Google Scholar 

Ouaissi MA, Capron A (1985) Fibronectins: structure and functions. Ann l’Inst Pasteur Immunol 136(2):169–185

Article  Google Scholar 

Bader JM, Geyer PE, Müller JB, Strauss MT, Koch M, Leypoldt F et al (2020) Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer’s disease. Mol Syst Biol. https://doi.org/10.15252/msb.20199356

Article  PubMed  PubMed Central