Deployment of metabolic heat rate based soft sensor for estimation and control of specific growth rate in glycoengineered Pichia pastoris for human interferon alpha 2b production
CPP
Critical Process Parameter
CER
Carbon di-oxide Evolution Rate
DS
Dielectric Spectroscopy
ELISA
Enzyme Linked Immunosorbent Assay
HPLC
High Performance Liquid Chromatography
PAT
Process Analytical Technology
PID
Proportional Integral Derivative
SCADA
Supervisory Control and Data Acquisition
RMSE
Root Mean Square Error
RPM
Revolutions Per Minute
VCC
Viable Cell Concentration
YPD
Yeast Extract Peptone Dextrose
YPG
Yeast Extract Peptone Glycerol
USFDA
United States Food and Drug Administration
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