Nocturia severely impairs the sleep quality of nursing home residents: results from a multi-center study

Sleep disturbances are common in older adults living in nursing homes. Their prevalence is estimated between 24% and 76% depending on the studies.1,2 Among nursing home residents, the prescription of hypnosedatives is up to 70%.3 In addition, these disorders are more severe in these patients than in community-dwelling older people.4 Sleep quality is a crucial aspect of well-being and health. Impaired sleep is associated with a broad range of adverse health effects in older adults including short- and long-term cognitive dysfunction,5,6 decline in physical function,7,8 increased fall risk,9 poor quality of life,10 mood disorders, long-term care institutionalization and mortality.2 Beyond the already known factors affecting sleep quality (self-rated health-status,11, 12, 13 hypnosedative use,12,14 pain,15 etc.), nocturia is important to consider but little studied among nursing home residents. However, nocturia is known to affect sleep duration and quality in “younger” adults.16,17 This symptom is defined by the International Continence Society as “the number of times an individual passes urine during their main sleep period, from the time they have fallen asleep up to the intention to rise from that period”, and is one of the most frequent and disturbing lower urinary tract symptoms.18,19 Although nocturia is a common condition in different patient populations, the older population is affected more significantly, with a prevalence of up to 60% of patients over 70 years of age.20 Nocturia is associated with an increased risk of all-cause morbidity and mortality21 and an increased risk of falls and hip fracture in older adults.22,23 Current literature has identified a diverse array of risk factors to nocturia, including aging, bladder overactivity,24 comorbidities,24 in particular cognitive dysfunction25 and depression,24 sleep disturbances and hypnosedative use.24 Poor sleep and nocturia frequently coexist among older adults residing in nursing homes, as some studies have identified sleep disturbances in upwards of three-fourths of nursing home participants,1,2 and one cross-sectional survey reported that nursing home residents with poor sleep perceived nocturia to be among the most common causes of disturbed sleep.26 Taken together, the direct relationship between poor sleep quality and nocturia among nursing home residents has not been well established. Accordingly, the objective of this study was to evaluate the association between self-reported sleep quality and nocturia in a population of nursing home residents. Controlling for age, gender, self-rated health status as a proxy of comorbidities and cognitive frailty as a proxy of cognitive status, hypnosedative and antidepressant use, it was hypothesized that nocturia would negatively affect sleep quality.

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