This study was sponsored by Shenzhen Jinrui Foundation Biotech Co., Ltd. (Shenzhen, China). This research was supported by the Youth Program of National Natural Science Foundation of China (no. 81903722). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.