The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study

Paparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. Eur J Cardiothorac Surg. 2002;21:232–44.

CAS  PubMed  Article  Google Scholar 

Zahler S, Massoudy P, Hartl H, Hahnel C, et al. Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass. Cardiovasc Res. 1999;41:722–30.

CAS  PubMed  Article  Google Scholar 

Goldstein SA, Beshish AG, Bush LB, Lowery RE, Wong JH, Schumacher KR, Halligan NLN, Cornell TT, Rocchini AP. Analysis of inflammatory cytokines in postoperative fontan pleural drainage. Pediatr Cardiol. 2019;40(4):744–52.

PubMed  Article  Google Scholar 

Martin BJ, McBrien A, Marchak BE, Atallah J, Al Aklabi M, Mackie AS. Predicting post-fontan length of stay: the limits of measured variables. Pediatr Cardiol. 2019;40(6):1208–16.

PubMed  Article  Google Scholar 

Ma M, Guavreau K, Allan CK, Mayer JE, Jenkins JK. Causes of death after congenital heart surgery. Ann Thorac Surg. 2007;83:1438–45.

PubMed  Article  Google Scholar 

Salvin JW, Scheurer MA, Laussen PC, et al. Factors associated with prolonged recovery after the Fontan operation. Circulation. 2008;118(14 Suppl):S171–6.

PubMed  Google Scholar 

Veldtman GR, Opotowsky AR, Wittekind SG, et al. Cardiovascular adaptation to the Fontan circulation. Congenit Heart Dis. 2017;12:699–710.

PubMed  Article  Google Scholar 

Lee A, Butt W. Nitric oxide a new role in intensive care. Crit Care Resusc. 2020;22(1):72–9.

PubMed  Google Scholar 

Wang W, Lee Y, Lee Ch. Effects of nitric oxide on stem cell therapy. Biotechnol Adv. 2015;33(8):1685–96.

CAS  PubMed  Article  Google Scholar 

Vercaemst L. Hemolysis in cardiac surgery patients undergoing cardiopulmonary bypass: a review in search of a treatment algorithm. J Extra Corpor Technol. 2008;40:257–67.

PubMed  PubMed Central  Google Scholar 

Fransen EJ, Ganushchak YM, Vijay V, de Jong DS, Buurman WA, Maessen JG. Evaluation of a new condensed extra-corporeal circuit for cardiac surgery: a pro-spective randomized clinical pilot study. Perfusion. 2005;20:91–9.

PubMed  Article  Google Scholar 

Reiter CD, Wang X, Tanus-Santos JE, Hogg N, Cannon RO 3rd, Schechter AN, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med. 2002;8:1383–9.

CAS  PubMed  Article  Google Scholar 

Minneci PC, Deans KJ, Zhi H, Yuen PS, Star RA, Banks SM, et al. Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin. J Clin Invest. 2005;115:3409–17.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Checchia P, Bronicki R, Muenzer J, Dixon D, Raithel S, Gandhi S, Huddleston C. Nitric oxide delivery during cardiopulmonary bypass reduces postoperative morbidity in children—a randomised controlled trial. J Thorac Cardiovasc Surg. 2013;146(3):530–6.

CAS  PubMed  Article  Google Scholar 

Brown KL, Pagel C, Brimmell R, Bull K, Davis P, Franklin RC, Hoskote A, Khan N, Rodrigues W, Thorne S, Smith L, Chigaru L, Utley M, Wray J, Tsang V, Mclean A. Definition of important early morbidities related to paediatric cardiac surgery. Cardiol Young. 2017;27(4):747–56.

PubMed  Article  Google Scholar 

Chan JL, Miller JG, Murphy M, Greenberg A, Iraola M, Horvath KA. A multidisciplinary protocol-driven approach to improve extubation times after cardiac surgery. Ann Thorac Surg. 2018;105(6):1684–90.

PubMed  Article  Google Scholar 

Bartz RR, Ferreira RG, Schroder JN, Davies J, Liu WW, Camara A, Welsby IJ. Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study. J Crit Care. 2015;30(5):940–4.

PubMed  Article  Google Scholar 

Ferreira FV, Sugo EK, Aragon DC, Carmona F, Carlotti APCP. Spontaneous breathing trial for prediction of extubation success in pediatric patients following congenital heart surgery: a randomized controlled trial. Pediatr Crit Care Med. 2019;20(10):940–6.

PubMed  Article  Google Scholar 

Gupta P, McDonald R, Goyal S, Gossett JM, Imamura M, Agarwal A, Butt W, Bhutta AT. Extubation failure in infants with shunt-dependent pulmonary blood flow and univentricular physiology. Cardiol Young. 2014;24(1):64–72.

PubMed  Article  Google Scholar 

Kolcz J., Karnas E., Borowka M., Stycula W., Zuba - Surba E., Skalski J. The protective effect of nitric oxide inhaled into oxygenator during Fontan surgery in patients with single ventricle defects. 24th WSCTS World Congress, Geneva, 6–9th September, 2014.

Kolcz J, Tomkiewicz-Pajak L, Wojcik E, Podolec P, Skalski J. Prognostic significance and correlations of neurohumoral factors in early and late postoperative period after Fontan procedure. Interact Cardiovasc Thorac Surg. 2011;13(1):40–5.

PubMed  Article  Google Scholar 

d’Udekem Y, Iyengar AJ, Cochrane AD, Grigg LE, Ramsay JM, Wheaton GR, Penny DJ, Brizard CP. The Fontan procedure: contemporary techniques have improved long-term outcomes. Circulation. 2007;116:I157–64.

PubMed  Article  Google Scholar 

Gaynor JW, Bridges ND, Cohen MI, Mahle WT, Decampli WM, Steven JM, Nicolson SC, Spray TL. Predictors of outcome after the Fontan operation: is hypoplastic left heart syndrome still a risk factor? J Thorac Cardiovasc Surg. 2002;123:237–45.

PubMed  Article  Google Scholar 

Fedderly RT, Whitstone BN, Frisbee SJ, Tweddell JS, Litwin SB. Factors related to pleural effusions after Fontan procedure in the era of fenestration. Circulation. 2001;104(12 Suppl 1):I148-151.

CAS  PubMed  Article  Google Scholar 

Garofalo CA, Cabreriza SE, Quinn TA, Weinberg AD, Printz BF, Hsu DT, Quaegebeur JM, Mosca RS, Spotnitz HM. Ventricular diastolic stiffness predicts perioperative morbidity and duration of pleural effusions after the Fontan operation. Circulation. 2006;114(1 Suppl):I56-61.

PubMed  Google Scholar 

Newburger JW, Wypij D, Bellinger DC, du Plessis AJ, Kuban KC, Rappaport LA, Almirall D, Wessel DL, Jonas RA, Wernovsky G. Length of stay after infant heart surgery is related to cognitive outcome at age 8 years. J Pediatr. 2003;143:67–73.

PubMed  Article  Google Scholar 

Seghaye MC. The clinical implications of the systemic inflammatory reaction related to cardiac operations in children. Cardiol Young. 2003;13:228–39.

PubMed  Article  Google Scholar 

Gott JP, Cooper WA, Schmidt FE Jr, et al. Modifying risk for extracorporeal circulation: trial of four antiinflammatory strategies. Ann Thorac Surg. 1998;66(3):747–53.

CAS  PubMed  Article  Google Scholar 

García-Camacho C, Marín-Paz A-J, Lagares-Franco C, Abellán-Hervás M-J, Sáinz-Otero A-M. Continuous ultrafiltration during extracorporeal circulation and its effect on lactatemia: a randomized controlled trial. PLoS ONE. 2020;15(11):e0242411.

PubMed  PubMed Central  Article  Google Scholar 

Hennein HA, Ebba H, Rodriguez JL, et al. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revasculation. J Thorac Cardiovasc Surg. 1994;108:626–35.

CAS  PubMed  Article  Google Scholar 

Finn A, Naik S, Klein N, Levinsky RJ, Strobel S, Elliott M. Interleukin-8 release and neutrophil degranulation after pediatric cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1993;105:234–41.

CAS  PubMed  Article  Google Scholar 

Rajasingh J, Thangavel J, Siddiqui MR, et al. Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells. PLoS ONE. 2011;6: e22550.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Verma SK, Krishnamurthy P, Barefield D, et al. Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB. Circulation. 2012;126:418–29.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Bolli R. Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischaemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol. 2001;33(11):1897–918.

CAS  PubMed  Article  Google Scholar 

Gianetti J, Del Sarto P, Bevilacqua S, Vassalle C, De Filippis R, Kacila M, Farreti PA, Clerico A, Glauber M. Biagini A Supplemental nitric oxide and its effect on myocardial injury and function in patients undergoing cardiac surgery with extracorporeal circulation. J Thorac Cardiovasc Surg. 2004;127(1):44–50.

CAS  PubMed  Article  Google Scholar 

Rassaf T, Kleinbongard P, Kelm M. Circulating NO pool in humans. Kidney Blood Press Res. 2005;28:341–8.

CAS  PubMed  Article  Google Scholar 

Kim JH, Bachmann RA, Chen J. Interleukin-6 and insulin resistance. Vitam Horm. 2009;80:613–33.

CAS  PubMed  Article  Google Scholar 

Laffey JG, Boylan JF, Cheng DC. The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist. Anesthesiology. 2002;97:215.

CAS  PubMed  Article  Google Scholar 

Wan S, LeClerc JL, Vincent JL. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest. 1997;112:676.

CAS  PubMed  Article 

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