Ference BA, Kastelein JJP, Catapano AL. Lipids and lipoproteins in 2020. JAMA. 2020;324(6):595–6.

PubMed  Article  Google Scholar 

Shengshou H. China TWCotRoCHaDi. Report on cardiovascular health and diseases burden in China: an updated summary of 2020. Chin Circ J. 2021;36(6):521–45.

Google Scholar 

Defesche JC, Gidding SS, Harada-Shiba M, Hegele RA, Santos RD, Wierzbicki AS. Familial hypercholesterolaemia. Nat Rev Dis Primers. 2017;3:17093.

PubMed  Article  Google Scholar 

Murray CJ, Lopez AD. Measuring the global burden of disease. N Engl J Med. 2013;369(5):448–57.

CAS  PubMed  Article  Google Scholar 

Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Back M, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42(34):3227–337.

PubMed  Article  Google Scholar 

NCDRF Collaboration. Repositioning of the global epicentre of non-optimal cholesterol. Nature. 2020;582(7810):73–7.

Article  Google Scholar 

Mortensen MB, Nordestgaard BG, Afzal S, Falk E. ACC/AHA guidelines superior to ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans: the Copenhagen general population study. Eur Heart J. 2017;38(8):586–94.

CAS  PubMed  Google Scholar 

Rossello X. Lifetime risk estimation in atherosclerotic cardiovascular disease: where inflammation meets lipoprotein(a). J Am Coll Cardiol. 2021;78(11):1095–6.

PubMed  Article  Google Scholar 

Ibanez B, Fernandez-Ortiz A, Fernandez-Friera L, Garcia-Lunar I, Andres V, Fuster V. Progression of early subclinical atherosclerosis (PESA) study: JACC focus seminar 7/8. J Am Coll Cardiol. 2021;78(2):156–79.

PubMed  Article  Google Scholar 

Collins R, Reith C, Emberson J, Armitage J, Baigent C, Blackwell L, et al. Interpretation of the evidence for the efficacy and safety of statin therapy. Lancet. 2016;388(10059):2532–61.

CAS  PubMed  Article  Google Scholar 

Pergolizzi JV Jr, Coluzzi F, Colucci RD, Olsson H, LeQuang JA, Al-Saadi J, et al. Statins and muscle pain. Expert Rev Clin Pharmacol. 2020;13(3):299–310.

CAS  PubMed  Article  Google Scholar 

Lv S, Yu H, Liu X, Gao X. The study on the mechanism of hugan tablets in treating drug-induced liver injury induced by atorvastatin. Front Pharmacol. 2021;12: 683707.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020;41(1):111–88.

PubMed  Article  Google Scholar 

Soppert J, Lehrke M, Marx N, Jankowski J, Noels H. Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting. Adv Drug Deliv Rev. 2020;159:4–33.

CAS  PubMed  Article  Google Scholar 

Huang K, Zhang P, Zhang Z, Youn JY, Wang C, Zhang H, et al. Traditional Chinese medicine (TCM) in the treatment of COVID-19 and other viral infections: efficacies and mechanisms. Pharmacol Ther. 2021;225: 107843.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Wang S, Fu JL, Hao HF, Jiao YN, Li PP, Han SY. Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy. Pharmacol Res. 2021;170: 105728.

CAS  PubMed  Article  Google Scholar 

Liu C, Huang Y. Chinese herbal medicine on cardiovascular diseases and the mechanisms of action. Front Pharmacol. 2016;7:469.

PubMed  PubMed Central  Article  Google Scholar 

Xie G, Tang X, Liang X, Liu H, Zhang S. The origination, connotation, and definition of one root of medicine and food. Mod Chin Med. 2020;22(09):1423.

Google Scholar 

Yang M, Sheng P. Medicinal and edible resources in Xinjiang:current status and prospects. Chin J Exp Tradit Med Formulae. 2021;27(13):234–43.

Google Scholar 

Pollastro F, Minassi A. Exploring the universe of natural products: recent advances in synthesis, isolation and structural elucidation. Plants (Basel). 2021;10(11):2368.

Article  Google Scholar 

Yuan H, Ma Q, Ye L, Piao G. The traditional medicine and modern medicine from natural products. Molecules. 2016;21(5):559.

PubMed Central  Article  Google Scholar 

Atanasov AG, Zotchev SB, Dirsch VM, Supuran CT. Natural products in drug discovery: advances and opportunities. Nat Rev Drug Discov. 2021;20(3):200–16.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Yang G, Su F, Chen M. Origin and prospect of homology medicine and food. Mod Chin Med. 2021;23(11):1851–6.

Google Scholar 

Mollazadeh H, Mahdian D, Hosseinzadeh H. Medicinal plants in treatment of hypertriglyceridemia: A review based on their mechanisms and effectiveness. Phytomedicine. 2019;53:43–52.

CAS  PubMed  Article  Google Scholar 

El-Tantawy WH, Temraz A. Natural products for controlling hyperlipidemia: review. Arch Physiol Biochem. 2019;125(2):128–35.

CAS  PubMed  Article  Google Scholar 

Zhang Y, Kishi H, Kobayashi S. Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders. Pharmacol Res. 2018;134:200–11.

PubMed  Article  Google Scholar 

Hunter PM, Hegele RA. Functional foods and dietary supplements for the management of dyslipidaemia. Nat Rev Endocrinol. 2017;13(5):278–88.

CAS  PubMed  Article  Google Scholar 

Xie W, Zhao Y, Du L. Emerging approaches of traditional Chinese medicine formulas for the treatment of hyperlipidemia. J Ethnopharmacol. 2012;140(2):345–67.

PubMed  Article  Google Scholar 

National Health Commission of P. R. China. Management approach of food and Chinese medicine homologous catalogue according to tradition. 2014. http://www.nhc.gov.cn/wjw/yjzj/201411/67ac54fb05ed46929adc63f2db31d4bf.shtml. Accessed on 26 Apr 2022.

National Health Commission of P. R. China. List of 9 pilot food and Chinese medicine homologous substances according to tradition. 2020. http://www.nhc.gov.cn/sps/s7885/202001/1ec2cca04146450d9b14acc2499d854f.shtml. Accessed on 26 Apr 2022.

Huang L, Chen M. Interpretation of medicine and food homologous substances. 1st ed. Beijing: People’s Medical Publishing House; 2021. p. 28–468.

Google Scholar 

Pharmacopoeia Committee of P. R. China. Pharmacopoeia of People’s Republic of China. Beijing: China Medical Science and Technology Press; 2020. p. 12–315.

Google Scholar 

Shalaby MA, Saifan HY. Some pharmacological effects of cinnamon and ginger herbs in obese diabetic rats. J Intercult Ethnopharmacol. 2014;3(4):144–9.

PubMed  PubMed Central  Article  Google Scholar 

Ranasinghe P, Perera S, Gunatilake M, Abeywardene E, Gunapala N, Premakumara S, et al. Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glucose and lipids in a diabetic and healthy rat model. Pharmacognosy Res. 2012;4(2):73–9.

PubMed  PubMed Central  Article  Google Scholar 

Hamidpour R, Hamidpour M, Hamidpour S, Shahlari M. Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer’s disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities. J Tradit Complement Med. 2015;5(2):66–70.

PubMed  PubMed Central  Article  Google Scholar 

Liu Y, An T, Wan D, Yu B, Fan Y, Pei X. Targets and mechanism used by cinnamaldehyde, the main active ingredient in Cinnamon, in the treatment of breast cancer. Front Pharmacol. 2020;11(1751): 582719.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Mbaveng AT. Medicinal spices and vegetables from Africa: therapeutic potential against metabolic, inflammatory, infectious and systemic diseases. London, UK: Academic Press; 2017. p. 385–95.

Google Scholar 

Naeef AF, Mohammed AH, Mubarak AN. Effects of cinnamon (Cinnamomum cassia) consumption on serum lipid profiles in Albino rats. J Lipids. 2020;2020:8469830.

Google Scholar 

Joohee O, Hyun-Sook K. Anti-obese effect of cinnamon extracts dietary supplementation on serum lipids and body weight gain in high-fat-iet Induced obese mice model. Curr Dev Nutr. 2021;5(2):1236.

Google Scholar 

Zeynep T, Cemal O, Nurhan S, Vijaya J, Kazim S. Cinnamon polyphenol extract inhibits hyperlipidemia and inflammation by modulation of transcription factors in high-fat diet-fed rats. Oxid Med Cell Longev. 2017;2017:1583098.

Google Scholar 

Pulungan A, Pane YS. The benefit of cinnamon (Cinnamomum burmannii) in lowering total cholesterol levels after consumption of high-fat containing foods in white mice (Mus musculus) models. F1000Res. 2020;9:168.

CAS  PubMed  PubMed Central  Google Scholar 

Abdelgadir AA, Hassan HM, Eltaher AM, Mohammed KG, Mohammed LA, Hago TB, et al. Hypolipidemic effect of Cinnamon (Cinnamomum zeylanicum) bark ethanolic extract on Triton X-100 induced hyperlipidemia in Albino rats. Med Aromat Plants. 2020;9(3):351.

Google Scholar 

Mendis AWPK, Galbada ASP, Daya RW. Bark extracts of Ceylon Cinnamon possess antilipidemic activities and bind bile acids in vitro. Evid Based Complement Alternat Med: eCAM. 2017;2017:7347219.

Google Scholar 

Verma S, Angadi S, Patil V, Mokashi A, Mathad J, Mummigatti U. Growth, yield and quality of chrysanthemum (Chrysanthemum morifolium Ramat) Cv. Raja as influenced by integrated nutrient management. Karnataka J Agric Sci. 2012;24(5):681–3.

Google Scholar 

Yuan H, Jiang S, Liu Y, Daniyal M, Jian Y, Peng C, et al. The flower head of Chrysanthemum morifolium Ramat. (Juhua): A paradigm of flowers serving as Chinese dietary herbal medicine. J Ethnopharmacol. 2020;261:113043.

Lin LZ, Harnly JM. Identification of the phenolic components of chrysanthemum flower (Chrysanthemum morifolium Ramat). Food Chem. 2010;120(1):319–26.

CAS  Article  Google Scholar 

Gong J, Chu B, Gong L, Fang Z, Zhang X, Qiu S, et al. Comparison of phenolic compounds and the antioxidant activities of fifteen Chrysanthemum morifolium Ramat cv. ‘Hangbaiju’ in China. Antioxidants. 2019;8(8):325.

CAS  PubMed Central