Jiao X, Ke H, Qin Y, Chen Z-J. Molecular genetics of premature ovarian insufficiency. Trends Endocrinol Metab. 2018;29:795–807.

CAS  PubMed  Article  Google Scholar 

Rebar RW. Premature ovarian failure. Obstet Gynecol. 2009;113:1355–63.

PubMed  Article  Google Scholar 

Webber L, Davies M, Anderson R, Bartlett J, Braat D, Cartwright B, Cifkova R, de Muinck K-S, Hogervorst E, Janse F, et al. ESHRE Guideline: management of women with premature ovarian insufficiency. Human reproduction (Oxford, England). 2016;31:926–37.

CAS  Article  Google Scholar 

Sharif K, Watad A, Bridgewood C, Kanduc D, Amital H, Shoenfeld Y. Insights into the autoimmune aspect of premature ovarian insufficiency. Best Pract Res Clin Endocrinol Metab. 2019;33: 101323.

CAS  PubMed  Article  Google Scholar 

Schover LR. Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility. J Clin Oncol. 2008;26:753–8.

PubMed  Article  Google Scholar 

Podfigurna-Stopa A, Czyzyk A, Grymowicz M, Smolarczyk R, Katulski K, Czajkowski K, Meczekalski B. Premature ovarian insufficiency: the context of long-term effects. J Endocrinol Invest. 2016;39:983–90.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Groff AA, Covington SN, Halverson LR, Fitzgerald OR, Vanderhoof V, Calis K, Nelson LM. Assessing the emotional needs of women with spontaneous premature ovarian failure. Fertil Steril. 2005;83:1734–41.

PubMed  Article  Google Scholar 

Li XT, Li PY, Liu Y, Yang HS, He LY, Fang YG, Liu J, Liu BY, Chaplin JE. Health-related quality-of-life among patients with premature ovarian insufficiency: a systematic review and meta-analysis. Qual Life Res. 2020;29:19–36.

CAS  PubMed  Article  Google Scholar 

Honigberg MC, Zekavat SM, Aragam K, Finneran P, Klarin D, Bhatt DL, Januzzi JL, Scott NS, Natarajan P. Association of premature natural and surgical menopause with incident cardiovascular disease. JAMA. 2019;322:2411–21.

PubMed  PubMed Central  Article  Google Scholar 

Roeters van Lennep JE, Heida KY, Bots ML, Hoek A. Cardiovascular disease risk in women with premature ovarian insufficiency: a systematic review and meta-analysis. Eur J Prev Cardiol. 2016;23:178–86.

PubMed  Article  Google Scholar 

Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ (Clinical research ed). 2021;372: n160.

Google Scholar 

Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014;14:135.

PubMed  PubMed Central  Article  Google Scholar 

The Newcastle-Ottawa scale (NOS) for assessing the quality if nonrandomized studies in meta-analyses [http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp]

AbdulAzeez IM, Biliaminu SA, Okesina AB, Olatinwo AWO, Omokanye LO. Lipid profile in subfertile clients with premature ovarian failure: University of Ilorin teaching hospital experience. J Krishna Inst Med Scie Uni. 2018;7:62–7.

CAS  Google Scholar 

Ağaçayak E, Görük NY, Küsen H, Tunç SY, Başaranoğlu S, İçen MS, Yıldızbakan A, Yüksel H, Kalkanlı S, Gül T. Role of inflammation and oxidative stress in the etiology of primary ovarian insufficiency. Turk J Obstet Gynecol. 2016;13:109–15.

PubMed  PubMed Central  Article  Google Scholar 

Ates S, Yesil G, Sevket O, Molla T, Yildiz S. Comparison of metabolic profile and abdominal fat distribution between karyotypically normal women with premature ovarian insufficiency and age matched controls. Maturitas. 2014;79:306–10.

PubMed  Article  Google Scholar 

Bozkaya V, Yumusak OH, Ozaksit G, Tenekecioğlu E, Gül Ibrişim E, Alkan M, Oskovi-Kaplan ZA, Erel Ö. The role of oxidative stress on subclinical atherosclerosis in premature ovarian insufficiency and relationship with carotid intima-media thickness. Gynecol Endocrinol. 2020;36:687–92.

CAS  PubMed  Article  Google Scholar 

Cekici Y, Kilic S, Ovayolu A, Saracoglu E, Duzen İV, Yilmaz M, Kaya BC, Bozkurt D. Prediction of lipoprotein-associated phospholipase a2 and inflammatory markers in subclinical atherosclerosis in premature ovarian failure patients. Acta Cardiologica Sinica. 2021;37:30–7.

PubMed  PubMed Central  Google Scholar 

Czyzyk A, Filipowicz D, Podfigurna A, Ptas P, Piestrzynska M, Smolarczyk R, Genazzani AR, Meczekalski B. Brain-derived neurotrophic factor (BDNF) plasma concentration in patients diagnosed with premature ovarian insufficiency (POI). Gynecol Endocrinol. 2017;33:413–7.

CAS  PubMed  Article  Google Scholar 

Daan N, Muka T, Koster M, Van Lennep JR, Lambalk C, Laven J, Fauser C, Meun C, De Rijke Y, Boersma E, et al. Cardiovascular risk in women with premature ovarian insufficiency compared to premenopausal women at middle age. Maturitas. 2017;100:109.

Article  Google Scholar 

Goldmeier S, De Angelis K, Casali KR, Vilodre C, Consolim-Colombo F, Klein AB, Plentz R, Spritzer P, Irigoyen MC. Cardiovascular autonomic dysfunction in primary ovarian insufficiency: clinical and experimental evidence. Am J Transl Res. 2014;6:91–101.

Google Scholar 

Gulhan I, Bozkaya G, Uyar I, Oztekin D, Pamuk BO, Dogan E. Serum lipid levels in women with premature ovarian failure. Menopause. 2012;19:1231–4.

PubMed  Article  Google Scholar 

Huang Y, Lv Y, Qi T, Luo Z, Meng X, Ying Q, Li D, Li C, Lan Y, Chu K, et al. Metabolic profile of women with premature ovarian insufficiency compared with that of age-matched healthy controls. Maturitas. 2021;148:33–9.

CAS  PubMed  Article  Google Scholar 

Kalantaridou SN, Naka KK, Papanikolaou E, Kazakos N, Kravariti M, Calis KA, Paraskevaidis EA, Sideris DA, Tsatsoulis A, Chrousos GP, Michalis LK. Impaired endothelial function in young women with premature ovarian failure: normalization with hormone therapy. J Clin Endocrinol Metab. 2004;89:3907–13.

CAS  PubMed  Article  Google Scholar 

Knauff EA, Westerveld HE, Goverde AJ, Eijkemans MJ, Valkenburg O, van Santbrink EJ, Fauser BC, van der Schouw YT. Lipid profile of women with premature ovarian failure. Menopause. 2008;15:919–23.

PubMed  Article  Google Scholar 

Kulaksizoglu M, Ipekci SH, Kebapcilar L, Kebapcilar AG, Korkmaz H, Akyurek F, Baldane S, Gonen MS. Risk factors for diabetes mellitus in women with primary ovarian insufficiency. Biol Trace Elem Res. 2013;154:313–20.

CAS  PubMed  Article  Google Scholar 

Kunicki M, Rudnicka E, Skórska J, Calik-Ksepka AI, Smolarczyk R. Insulin resistance indexes in women with premature ovarian insufficiency - a pilot study. Ginekol Pol. 2018;89:364–9.

PubMed  Article  Google Scholar 

Luo X, Cheng R, Zhang J, Ma Y, Zhang J, Luo Y, Xu L. Evaluation of body composition in POF and its association with bone mineral density and sex steroid levels. Gynecol Endocrinol. 2018;34:1027–30.

CAS  PubMed  Article  Google Scholar 

Podfigurna A, Stellmach A, Szeliga A, Czyzyk A, Meczekalski B. Metabolic profile of patients with premature ovarian Insufficiency. J Clin Med. 2018;7:374.

CAS  PubMed Central  Article  Google Scholar 

Podfigurna A, Maciejewska-Jeske M, Nadolna M, Mikolajska-Ptas P, Szeliga A, Bilinski P, Napierala P, Meczekalski B. Impact of hormonal replacement therapy on bone mineral density in premature ovarian insufficiency patients. J Clin Med. 2020;9:1–10.

Article  Google Scholar 

Szlendak-Sauer K, Jakubik D, Kunicki M, Skórska J, Smolarczyk R. Autoimmune polyglandular syndrome type 3 (APS-3) among patients with premature ovarian insufficiency (POI). Eur J Obstet Gynecol Reprod Biol. 2016;203:61–5.

CAS  PubMed  Article  Google Scholar 

Tunc SY, Goruk NY, Agacayak E, Icen MS, Findik FM, Kusen H, Evsen MS, Yuksel H, Gul T. Significance of growth differentiation factor 15 in primary ovarian insufficiency: inflammatory, biochemical, and hormonal correlates. Clin Exp Obstet Gynecol. 2017;44:730–3.

Article  Google Scholar 

Xu Z, Wang Q, Zhu L, Ma L, Ye X, Li C, Lan Y, Huang Y, Liu J, Zhou J. Correlation of serum vitamin D levels with ovarian reserve markers in patients with primary ovarian insufficiency. Int J Clin Exp Med. 2019;12:4147.

CAS  Google Scholar 

Yorgun H, Gürses KM, Canpolat U, YapIcI Z, Bozdaǧ G, Kaya EB, Aytemir K, Oto A, KabakçI G, Tokgözoǧlu L. Evaluation of cardiac autonomic function by various indices in patients with primary premature ovarian failure. Clin Res Cardiol. 2012;101:753–9.

PubMed  Article  Google Scholar 

Ambikairajah A, Walsh E, Cherbuin N. Lipid profile differences during menopause: a review with meta-analysis. Menopause (New York, NY). 2019;26:1327–33.

Google Scholar 

De Paoli M, Zakharia A, Werstuck GH. The role of estrogen in insulin resistance: a review of clinical and preclinical data. Am J Pathol. 2021;191:1490–8.

Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev. 2013;34:309–38.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Christ JP, Gunning MN, Palla G, Eijkemans MJC, Lambalk CB, Laven JSE, Fauser BCJM. Estrogen deprivation and cardiovascular disease risk in primary ovarian insufficiency. Fertil Steril. 2018;109:594.

CAS  PubMed  Article  Google Scholar 

Lei Z, Wu H, Yang Y, Hu Q, Lei Y, Liu W, Nie Y, Yang L, Zhang X, Yang C, et al. Ovariectomy impaired hepatic glucose and lipid homeostasis and altered the gut microbiota in mice with different diets. Front Endocrinol. 2021;12: 708838.

Article  Google Scholar 

Taneja C, Gera S, Kim S-M, Iqbal J, Yuen T, Zaidi M. FSH-metabolic circuitry and menopause. J Mol Endocrinol. 2019;63:R73–80.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Sun D, Bai M, Jiang Y, Hu M, Wu S, Zheng W, Zhang Z. Roles of follicle stimulating hormone and its receptor in human metabolic diseases and cancer. Am J Transl Res. 2020;12:3116–32.