Clemens Zwergel and Michael Schnekenburger contributed equally to this work.

Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy

Clemens Zwergel, Giulia Stazi, Roberta Mazzone, Rossella Fioravanti, Antonello Mai & Sergio Valente

Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, 9 rue Edward Steichen, L-2540, Luxembourg City, Luxembourg

Michael Schnekenburger & Cristina Florean

Department of Medicine of Precision, University of Studi della Campania Luigi Vanvitelli, Vico L. De Crecchio 7, 80138, Naples, Italy

Federica Sarno, Angela Nebbioso & Lucia Altucci

Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy

Cecilia Battistelli, Raffaele Strippoli & Marco Tripodi

Laboratory of Experimental Oncology, IRCCS - Istituto Ortopedico Rizzoli, via di Barbiano, 1/10, 40136, Bologna, Italy

Maria Cristina Manara & Katia Scotlandi

Center for High-Throughput Chemical Biology, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada

Christina Gros

Pierre Fabre Laboratories, 3 Avenue Hubert Curien, 31100, Toulouse, France

Frédéric Ausseil

National Institute for Infectious Diseases L. Spallanzani, IRRCCS, Via Portuense, 292, 00149, Rome, Italy

Raffaele Strippoli & Marco Tripodi

Division of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan

Toshikazu Ushijima

Pasteur Institute, Cenci-Bolognetti Foundation, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy

Marco Tripodi & Antonello Mai

Epigenetic Chemical Biology, Institut Pasteur, CNRS UMR3523, 28 rue du Docteur Roux, 75724, Paris, France

Paola B. Arimondo

Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, 08826, Korea

Marc Diederich