This work was supported by the National Institutes of Health/National Institute of Neurological Disorders and Stroke/National Institute for Mental Health (grants R01NS115746 and R01MH125515 to J.R.C. and grant F32NS116214 to W.X.), the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (APND grant A130141 to J.R.C.), and the Rachleff Family Endowment.