*Jiangsu Key Laboratory of Oral Diseases;

†Department of Oral and Maxillofacial Surgery; and

‡Department of Pathology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China.

Address correspondence and reprint requests to Yifei Du, MD, PhD, Number 1, Shanghai Road, Nanjing 210029, China; E-mail: [email protected] edu.cn

Z.W., J.X., and J.W. contributed equally to this article.Human rights statements and informed consent All procedures performed in this study involving human participants were in accordance with the ethical standards and approved by the Ethic in Research Committee of Stomatological Hospital, Nanjing Medical University, Nanjing, China (PJ2020–107–001) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

The work was supported in part by the National Natural Science Foundation of China (Grant No. 81800936) and by the Project Funded by Jiangsu Provincial Commission of Health and Family Planning, Nanjing, China (BJ18035).

The authors report no conflicts of interest.

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